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6-Alkyl- and 6-Arylandrost-4-ene-3,17-diones as Aromatase Inhibitors. Synthesis and Structure-Activity Relationships

Journal of medicinal chemistry, 1994-04, Vol.37 (9), p.1312-1319

1994

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Improved Synthesis and Molecular Modeling of 4β,19-Dihydroxyandrost-5-en-17-one, an Excellent Inhibitor of Aromatase

Chemical and Pharmaceutical Bulletin, 2002, Vol.50(5), pp.703-705

2002

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Synthesis of 19-oxygenated derivatives of the competitive inhibitor of aromatase, 5-androstene-4,17-dione

Steroids, 1999-05, Vol.64 (5), p.320-327

1999

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Production of 16β-(acetoxy)acetoxy derivatives by reaction of 17-keto steroid enol acetates with lead (IV) acetate

Steroids, 2001-10, Vol.66 (10), p.743-748

2001

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Deoxygenation of Steroidal Ring-D 16, 17-Ketols with Trimethylsilyl Iodide

Chemical and Pharmaceutical Bulletin, 1998/12/15, Vol.46(12), pp.1857-1861

1998

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Synthesis of 19-Oxygenated 4β, 5β-Epoxy Derivatives of 16α-Hydroxyandrostenedione as Mechanistic and Catalytic Probes for Aromatase Reaction

Chemical and Pharmaceutical Bulletin, 2000/09/01, Vol.48(9), pp.1359-1362

2000

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Mechanistic Studies of Deoxygenation of Steroidal Ring-D 16, 17-Ketols with trimethylsilyl Iodide

Chemical and Pharmaceutical Bulletin, 1999/04/15, Vol.47(4), pp.548-553

1999

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Reaction of androst-5-en-17-one with hypobromous acid and its use for synthesis of 19-oxygenated 5-ene and 4-en-6-one steroids

Steroids, 1998-02, Vol.63 (2), p.62-69

1998

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Synthesis and GC-MS of 6-Alkylestradiols, Possible Aromatase Reaction Products of 6-Alkylandrostenediones

Chemical and Pharmaceutical Bulletin, 1996/08/15, Vol.44(8), pp.1530-1534

1996

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Formation of 17β-Alkoxy-16-keto Steroids by Reaction of 16α-Hydroxy-17-keto and 17β-Hydroxy-16-keto Steroids with Trimethylsilyl Iodide in the Presence of Alkyl Alcohols

Chemical and Pharmaceutical Bulletin, 2000/08/01, Vol.48(8), pp.1215-1218

2000

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Synthesis of Deuterium-Labeled Androst-5-ene-17β, 19-diol and Its 4-Ene Isomer as Internal Standards for the Determination of the 19-Oxygenation of Aromatase Inhibitors Using GC-MS

Chemical and Pharmaceutical Bulletin, 1999/02/15, Vol.47(2), pp.263-266

1999

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Competing pathway involved in allylic acetoxylation of androst-5-en-17-one, and oxidation of allylic alcohols with chromium oxides

Steroids, 1995-08, Vol.60 (8), p.499-505

1995

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1,4-Addition reaction with thiols and conformational analysis with PM3 molecular orbital calculations of 19-oxygenated androst-4-ene-3,6,17-triones

Steroids, 1993-09, Vol.58 (9), p.423-428

1993

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Efficient C-21 deoxygenation of 21-alkoxy-20-keto corticoid steroids with trimethylsilyl iodide in the presence of methanol

Journal of organic chemistry, 1991-01, Vol.56 (1), p.334-338

1991

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Novel and regiospecific synthesis of 2-amino estrogens via Zincke nitration

Steroids, 1983-05, Vol.41 (5), p.675-682

1983

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Synthesis of Deuterium-Labeled 16α, 19-Dihydroxy C19 Steroids as Internal Standards for Gas Chromatography-Mass Spectrometry

Chemical and Pharmaceutical Bulletin, 1992/10/25, Vol.40(10), pp.2759-2763

1992

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Reaction of 16-bromo-17-oxo steroids with potassium cyanide

Journal of organic chemistry, 1986-04, Vol.51 (8), p.1360-1362

1986

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Synthesis of 16α,19-dihydroxy-4-androstene-3,17-dione and 3β,16α,19-trihydroxy-5-androsten-17-one and their 17β-hydroxy-16-keto isomers

Steroids, 1987, Vol.49 (4), p.247-257

1987

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Stereospecific 1, 2-Hydride Shift in the Rearrangement of 16β-Hydroxy-17-oxo Steroids to 17β-Hydroxy-16-ones with Acid and Base

Chemical and Pharmaceutical Bulletin, 1987/12/25, Vol.35(12), pp.4763-4768

1987

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Reaction of 21-Bromo-17α-methoxy-20-ketopregnenes with Sodium Methoxide or Potassium Acetate

Chemical and Pharmaceutical Bulletin, 1985/10/25, Vol.33(10), pp.4589-4592

1985

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Reactions of Enolizable Steroidal 4-En-3-ones and 17-Ones with Hypervalent Iodine

Chemical and Pharmaceutical Bulletin, 1988/09/25, Vol.36(9), pp.3381-3386

1988

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Oxygenation of 2, 4-Dibromoestrogens with Nitric Acid : A New Synthesis of 19-Nor Steroids

Chemical and Pharmaceutical Bulletin, 1989/08/25, Vol.37(8), pp.2058-2062

1989

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Synthesis of 16α-Hydroxyandrost-4-ene-3, 17, 19-trione and 3β, 16α-Dihydroxyandrost-5-ene-17, 19-dione : Potential Intermediates of Estriol Biosynthesis

Chemical and Pharmaceutical Bulletin, 1990/07/25, Vol.38(7), pp.2040-2042

1990

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Regiospecific Deoxygenation of the Dihydroxyacetone Moiety at C-17 of Corticoid Steroids with Iodotrimethylsilane

Chemical and Pharmaceutical Bulletin, 1986/09/25, Vol.34(9), pp.3722-3726

1986

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Synthesis of Deuterium-Labelled 16α-Hydroxy-4-androstene-3, 17-dione and 16α-Hydroxydehydroepiandrosterone

Chemical and Pharmaceutical Bulletin, 1985/02/25, Vol.33(2), pp.865-868

1985

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6-Alkyl- and 6-Arylandrost-4-ene-3,17-diones as Aromatase Inhibitors. Synthesis and Structure-Activity Relationships

Improved Synthesis and Molecular Modeling of 4β,19-Dihydroxyandrost-5-en-17-one, an Excellent Inhibitor of Aromatase

Synthesis of 19-oxygenated derivatives of the competitive inhibitor of aromatase, 5-androstene-4,17-dione

Production of 16β-(acetoxy)acetoxy derivatives by reaction of 17-keto steroid enol acetates with lead (IV) acetate

Deoxygenation of Steroidal Ring-D 16, 17-Ketols with Trimethylsilyl Iodide

Synthesis of 19-Oxygenated 4β, 5β-Epoxy Derivatives of 16α-Hydroxyandrostenedione as Mechanistic and Catalytic Probes for Aromatase Reaction

Mechanistic Studies of Deoxygenation of Steroidal Ring-D 16, 17-Ketols with trimethylsilyl Iodide

Reaction of androst-5-en-17-one with hypobromous acid and its use for synthesis of 19-oxygenated 5-ene and 4-en-6-one steroids

Synthesis and GC-MS of 6-Alkylestradiols, Possible Aromatase Reaction Products of 6-Alkylandrostenediones

Formation of 17β-Alkoxy-16-keto Steroids by Reaction of 16α-Hydroxy-17-keto and 17β-Hydroxy-16-keto Steroids with Trimethylsilyl Iodide in the Presence of Alkyl Alcohols

Synthesis of Deuterium-Labeled Androst-5-ene-17β, 19-diol and Its 4-Ene Isomer as Internal Standards for the Determination of the 19-Oxygenation of Aromatase Inhibitors Using GC-MS

Competing pathway involved in allylic acetoxylation of androst-5-en-17-one, and oxidation of allylic alcohols with chromium oxides

1,4-Addition reaction with thiols and conformational analysis with PM3 molecular orbital calculations of 19-oxygenated androst-4-ene-3,6,17-triones

Efficient C-21 deoxygenation of 21-alkoxy-20-keto corticoid steroids with trimethylsilyl iodide in the presence of methanol

Novel and regiospecific synthesis of 2-amino estrogens via Zincke nitration

Synthesis of Deuterium-Labeled 16α, 19-Dihydroxy C19 Steroids as Internal Standards for Gas Chromatography-Mass Spectrometry

Reaction of 16-bromo-17-oxo steroids with potassium cyanide

Synthesis of 16α,19-dihydroxy-4-androstene-3,17-dione and 3β,16α,19-trihydroxy-5-androsten-17-one and their 17β-hydroxy-16-keto isomers

Stereospecific 1, 2-Hydride Shift in the Rearrangement of 16β-Hydroxy-17-oxo Steroids to 17β-Hydroxy-16-ones with Acid and Base

Reaction of 21-Bromo-17α-methoxy-20-ketopregnenes with Sodium Methoxide or Potassium Acetate

Reactions of Enolizable Steroidal 4-En-3-ones and 17-Ones with Hypervalent Iodine

Oxygenation of 2, 4-Dibromoestrogens with Nitric Acid : A New Synthesis of 19-Nor Steroids

Synthesis of 16α-Hydroxyandrost-4-ene-3, 17, 19-trione and 3β, 16α-Dihydroxyandrost-5-ene-17, 19-dione : Potential Intermediates of Estriol Biosynthesis

Regiospecific Deoxygenation of the Dihydroxyacetone Moiety at C-17 of Corticoid Steroids with Iodotrimethylsilane

Synthesis of Deuterium-Labelled 16α-Hydroxy-4-androstene-3, 17-dione and 16α-Hydroxydehydroepiandrosterone

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