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Effect of regular organic solvents on cytochrome P450-mediated metabolic activities in rat liver microsomes

Drug metabolism and disposition, 2010-11, Vol.38 (11), p.1922

2010

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Development of a systematic approach to identify metabolites for herbal homologs based on liquid chromatography hybrid ion trap time-of-flight mass spectrometry: gender-related difference in metabolism of Schisandra lignans in rats

Drug metabolism and disposition, 2010-10, Vol.38 (10), p.1747

2010

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In vivo metabolism study of rhubarb decoction in rat using high-performance liquid chromatography with UV photodiode-array and mass-spectrometric detection: A strategy for systematic analysis of metabolites from traditional Chinese medicines in biological samples

Journal of Chromatography A, 2010-11, Vol.1217 (45), p.7144-7152

2010

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Effects of short-term and long-term pretreatment of Schisandra lignans on regulating hepatic and intestinal CYP3A in rats

Drug metabolism and disposition, 2009-12, Vol.37 (12), p.2399

2009

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In vitro metabolism of cyadox in rat, chicken and swine using ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry

Journal of pharmaceutical and biomedical analysis, 2012-08, Vol.67-68, p.175-185

2012

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Pharmacokinetics of atorvastatin and its hydroxy metabolites in rats and the effects of concomitant rifampicin single doses: relevance of first-pass effect from hepatic uptake transporters, and intestinal and hepatic metabolism

Drug metabolism and disposition, 2006-07, Vol.34 (7), p.1175

2006

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Cytochrome P4504f, a potential therapeutic target limiting neuroinflammation

Biochemical pharmacology, 2011-07, Vol.82 (1), p.53-64

2011

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Structural elucidation of metabolites of tanshinone I and its analogue dihydrotanshinone I in rats by HPLC―ESI-MSn

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010-04, Vol.878 (13-14), p.915-924

2010

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Metabolism of TM‐2, a potential antitumor drug, in rats by using LC–MS

Journal of separation science, 2014-03, Vol.37 (6), p.625-629

2014

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The effect of psychotropic drugs on cytochrome P450 2D (CYP2D) in rat brain

European journal of pharmacology, 2011-01, Vol.651 (1-3), p.51-58

2011

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Investigation of the disposition of loxapine, amoxapine and their hydroxylated metabolites in different brain regions, CSF and plasma of rat by LC–MS/MS

Journal of pharmaceutical and biomedical analysis, 2012-01, Vol.58 (25), p.83-93

2012

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Pharmacokinetics, metabolism, and excretion of anacetrapib, a novel inhibitor of the cholesteryl ester transfer protein, in rats and rhesus monkeys

Drug metabolism and disposition, 2010-03, Vol.38 (3), p.459

2010

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Validation of a novel in vitro assay using ultra performance liquid chromatography–mass spectrometry (UPLC/MS) to detect and quantify hydroxylated metabolites of BDE-99 in rat liver microsomes

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010-06, Vol.878 (19), p.1562-1568

2010

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Role of CYP3A and CYP2E1 in alcohol-mediated increases in acetaminophen hepatotoxicity: comparison of wild-type and Cyp2e1(-/-) mice

Drug metabolism and disposition, 2007-07, Vol.35 (7), p.1223

2007

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Isolation and identification of phase 1 metabolites of demethoxycurcumin in rats

Drug metabolism and disposition, 2007-09, Vol.35 (9), p.1564

2007

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Identification of in vivo and in vitro metabolites of triptolide by liquid chromatography–tandem mass spectrometry

Journal of pharmaceutical and biomedical analysis, 2012-11, Vol.70, p.624-630

2012

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Simultaneous determination of imperatorin and its 2 metabolites in dog plasma by using liquid chromatography–tandem mass spectrometry

Journal of pharmaceutical and biomedical analysis, 2012-11, Vol.70, p.640-646

2012

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Analysis of hydroxylated polybrominated diphenyl ethers in rat plasma by using ultra performance liquid chromatography–tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011-05, Vol.879 (15), p.1086-1090

2011

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Tentative identification of new metabolites of epimedin C by liquid chromatography–mass spectrometry

Journal of separation science, 2011-11, Vol.34 (22), p.3200-3207

2011

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l-DOPA administration enhances 6-hydroxydopamine generation

Brain research, 2005-11, Vol.1063 (2), p.180-186

2005

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Differential inductive profiles of hepatic cytochrome P450s by the extracts of Sophora flavescens in male and female C57BL/6JNarl mice

Journal of ethnopharmacology, 2009-12, Vol.126 (3), p.437-446

2009

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Detection of phenolic metabolites of styrene in mouse liver and lung microsomal incubations

Drug metabolism and disposition, 2010-11, Vol.38 (11), p.1934

2010

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Structural elucidation of in vitro and in vivo metabolites of cryptotanshinone by HPLC-DAD-ESI-MS

Journal of pharmaceutical and biomedical analysis, 2008-11, Vol.48 (3), p.885-896

2008

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Drug metabolism-based design, synthesis, and bioactivities of 1-(2,6-dimethylphenoxy)-2-(3,4-dimethoxyphenylethylamino)propane hydrochloride (DDPH) analogs as α₁-adrenoceptors antagonists

Bioorganic & medicinal chemistry, 2011-01, Vol.19 (2), p.783-788

2011

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Evaluation of the assumptions of an ontogeny model of rat hepatic cytochrome P450 activity

Drug metabolism and disposition, 2007-12, Vol.35 (12), p.2225

2007

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Effect of regular organic solvents on cytochrome P450-mediated metabolic activities in rat liver microsomes

Development of a systematic approach to identify metabolites for herbal homologs based on liquid chromatography hybrid ion trap time-of-flight mass spectrometry: gender-related difference in metabolism of Schisandra lignans in rats

In vivo metabolism study of rhubarb decoction in rat using high-performance liquid chromatography with UV photodiode-array and mass-spectrometric detection: A strategy for systematic analysis of metabolites from traditional Chinese medicines in biological samples

Effects of short-term and long-term pretreatment of Schisandra lignans on regulating hepatic and intestinal CYP3A in rats

In vitro metabolism of cyadox in rat, chicken and swine using ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry

Pharmacokinetics of atorvastatin and its hydroxy metabolites in rats and the effects of concomitant rifampicin single doses: relevance of first-pass effect from hepatic uptake transporters, and intestinal and hepatic metabolism

Cytochrome P4504f, a potential therapeutic target limiting neuroinflammation

Structural elucidation of metabolites of tanshinone I and its analogue dihydrotanshinone I in rats by HPLC―ESI-MSn

Metabolism of TM‐2, a potential antitumor drug, in rats by using LC–MS

The effect of psychotropic drugs on cytochrome P450 2D (CYP2D) in rat brain

Investigation of the disposition of loxapine, amoxapine and their hydroxylated metabolites in different brain regions, CSF and plasma of rat by LC–MS/MS

Pharmacokinetics, metabolism, and excretion of anacetrapib, a novel inhibitor of the cholesteryl ester transfer protein, in rats and rhesus monkeys

Validation of a novel in vitro assay using ultra performance liquid chromatography–mass spectrometry (UPLC/MS) to detect and quantify hydroxylated metabolites of BDE-99 in rat liver microsomes

Role of CYP3A and CYP2E1 in alcohol-mediated increases in acetaminophen hepatotoxicity: comparison of wild-type and Cyp2e1(-/-) mice

Isolation and identification of phase 1 metabolites of demethoxycurcumin in rats

Identification of in vivo and in vitro metabolites of triptolide by liquid chromatography–tandem mass spectrometry

Simultaneous determination of imperatorin and its 2 metabolites in dog plasma by using liquid chromatography–tandem mass spectrometry

Analysis of hydroxylated polybrominated diphenyl ethers in rat plasma by using ultra performance liquid chromatography–tandem mass spectrometry

Tentative identification of new metabolites of epimedin C by liquid chromatography–mass spectrometry

l-DOPA administration enhances 6-hydroxydopamine generation

Differential inductive profiles of hepatic cytochrome P450s by the extracts of Sophora flavescens in male and female C57BL/6JNarl mice

Detection of phenolic metabolites of styrene in mouse liver and lung microsomal incubations

Structural elucidation of in vitro and in vivo metabolites of cryptotanshinone by HPLC-DAD-ESI-MS

Drug metabolism-based design, synthesis, and bioactivities of 1-(2,6-dimethylphenoxy)-2-(3,4-dimethoxyphenylethylamino)propane hydrochloride (DDPH) analogs as α₁-adrenoceptors antagonists

Evaluation of the assumptions of an ontogeny model of rat hepatic cytochrome P450 activity

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