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Bias Factor and Therapeutic Window Correlate to Predict Safer Opioid Analgesics

Cell, 2017-11, Vol.171 (5), p.1165-1175.e13

2017

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Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria

Science signaling, 2016-11, Vol.9 (456), p.ra117

2016

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Real-Time Visualization of Dynamin-Catalyzed Membrane Fission and Vesicle Release

Cell, 2008-12, Vol.135 (7), p.1263-1275

2008

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Cargo and dynamin regulate clathrin-coated pit maturation

PLoS biology, 2009-03, Vol.7 (3), p.e57-e57

2009

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Dissecting dynamin's role in clathrin-mediated endocytosis

Biochemical Society transactions, 2009-10, Vol.37 (Pt 5), p.1022-1026

2009

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Dynamin regulates the dynamics and mechanical strength of the actin cytoskeleton as a multifilament actin-bundling protein

Nature cell biology, 2020-06, Vol.22 (6), p.674-688

2020

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Phosphatidylinositol-(4,5)-bisphosphate regulates clathrin-coated pit initiation, stabilization, and size

Molecular biology of the cell, 2011-07, Vol.22 (14), p.2588-2600

2011

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A dynamic actin cytoskeleton functions at multiple stages of clathrin-mediated endocytosis

Molecular biology of the cell, 2005-02, Vol.16 (2), p.964-975

2005

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Regulated portals of entry into the cell

Nature (London), 2003-03, Vol.422 (6927), p.37-44

2003

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Cargo- and adaptor-specific mechanisms regulate clathrin-mediated endocytosis

The Journal of cell biology, 2010-03, Vol.188 (6), p.919-933

2010

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Early severe inflammatory responses to uropathogenic E. coli predispose to chronic and recurrent urinary tract infection

PLoS pathogens, 2010-08, Vol.6 (8), p.e1001042

2010

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Agonist-directed signaling of the serotonin 2A receptor depends on β-arrestin-2 interactions in vivo

Proceedings of the National Academy of Sciences - PNAS, 2008-01, Vol.105 (3), p.1079-1084

2008

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Comparison of morphine, oxycodone and the biased MOR agonist SR-17018 for tolerance and efficacy in mouse models of pain

Neuropharmacology, 2021-03, Vol.185, p.108439-108439, Article 108439

2021

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GTPase Cycle of Dynamin Is Coupled to Membrane Squeeze and Release, Leading to Spontaneous Fission

Cell, 2008-12, Vol.135 (7), p.1276-1286

2008

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Isoform and splice-variant specific functions of dynamin-2 revealed by analysis of conditional knock-out cells

Molecular biology of the cell, 2008-12, Vol.19 (12), p.5347-5359

2008

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Regulation of macropinocytosis by p21-activated kinase-1

Molecular biology of the cell, 2000-10, Vol.11 (10), p.3341-3352

2000

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Differential curvature sensing and generating activities of dynamin isoforms provide opportunities for tissue-specific regulation

Proceedings of the National Academy of Sciences - PNAS, 2011-06, Vol.108 (26), p.E234-E242

2011

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Regulation of signal transduction by endocytosis

Current Opinion in Cell Biology, 2000-04, Vol.12 (2), p.204-210

2000

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Measuring the Hierarchy of Molecular Events During Clathrin‐Mediated Endocytosis

Traffic (Copenhagen, Denmark), 2011-07, Vol.12 (7), p.815-825

2011

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Functional Selectivity of 6′-Guanidinonaltrindole (6′-GNTI) at κ-Opioid Receptors in Striatal Neurons

The Journal of biological chemistry, 2013-08, Vol.288 (31), p.22387-22398

2013

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Hyperactivity in Mice Induced by Opioid Agonists with Partial Intrinsic Efficacy and Biased Agonism Administered Alone and in Combination with Morphine

Biomolecules (Basel, Switzerland), 2023-06, Vol.13 (6), p.935

2023

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Robust single-particle tracking in live-cell time-lapse sequences

Nature methods, 2008-08, Vol.5 (8), p.695-702

2008

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Hotspots Organize Clathrin‐Mediated Endocytosis by Efficient Recruitment and Retention of Nucleating Resources

Traffic (Copenhagen, Denmark), 2011-12, Vol.12 (12), p.1868-1878

2011

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Lubiprostone reverses the inhibitory action of morphine on intestinal secretion in guinea pig and mouse

The Journal of pharmacology and experimental therapeutics, 2010-07, Vol.334 (1), p.333-340

2010

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Dynamin and its partners: a progress report

Current opinion in cell biology, 1998-08, Vol.10 (4), p.504-512

1998

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Bias Factor and Therapeutic Window Correlate to Predict Safer Opioid Analgesics

Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria

Real-Time Visualization of Dynamin-Catalyzed Membrane Fission and Vesicle Release

Cargo and dynamin regulate clathrin-coated pit maturation

Dissecting dynamin's role in clathrin-mediated endocytosis

Dynamin regulates the dynamics and mechanical strength of the actin cytoskeleton as a multifilament actin-bundling protein

Phosphatidylinositol-(4,5)-bisphosphate regulates clathrin-coated pit initiation, stabilization, and size

A dynamic actin cytoskeleton functions at multiple stages of clathrin-mediated endocytosis

Regulated portals of entry into the cell

Cargo- and adaptor-specific mechanisms regulate clathrin-mediated endocytosis

Early severe inflammatory responses to uropathogenic E. coli predispose to chronic and recurrent urinary tract infection

Agonist-directed signaling of the serotonin 2A receptor depends on β-arrestin-2 interactions in vivo

Comparison of morphine, oxycodone and the biased MOR agonist SR-17018 for tolerance and efficacy in mouse models of pain

GTPase Cycle of Dynamin Is Coupled to Membrane Squeeze and Release, Leading to Spontaneous Fission

Isoform and splice-variant specific functions of dynamin-2 revealed by analysis of conditional knock-out cells

Regulation of macropinocytosis by p21-activated kinase-1

Differential curvature sensing and generating activities of dynamin isoforms provide opportunities for tissue-specific regulation

Regulation of signal transduction by endocytosis

Measuring the Hierarchy of Molecular Events During Clathrin‐Mediated Endocytosis

Functional Selectivity of 6′-Guanidinonaltrindole (6′-GNTI) at κ-Opioid Receptors in Striatal Neurons

Hyperactivity in Mice Induced by Opioid Agonists with Partial Intrinsic Efficacy and Biased Agonism Administered Alone and in Combination with Morphine

Robust single-particle tracking in live-cell time-lapse sequences

Hotspots Organize Clathrin‐Mediated Endocytosis by Efficient Recruitment and Retention of Nucleating Resources

Lubiprostone reverses the inhibitory action of morphine on intestinal secretion in guinea pig and mouse

Dynamin and its partners: a progress report

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