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Designing More Efficient Preclinical Experiments: A Simulation Study in Chemotherapy-Induced Myelosupression

Toxicological sciences, 2016-03, Vol.150 (1), p.109-116

2016

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Antisense oligonucleotide therapeutics in neurodegenerative diseases: the case of polyglutamine disorders

Brain (London, England : 1878), 2020-02, Vol.143 (2), p.407-429

2020

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The frontline of alternatives to animal testing: novel in vitro skin model application in drug development and evaluation

Toxicological sciences, 2023-11, Vol.196 (2), p.152-169

2023

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Of mice and human embryos: is there an ethically preferred order of preclinical research on new assisted reproductive technologies?

Human reproduction (Oxford), 2018-09, Vol.33 (9), p.1581-1585

2018

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The Role of Glia Underlying Acupuncture Analgesia in Animal Pain Models: A Systematic Review and Meta-Analysis

Pain medicine (Malden, Mass.), 2023-01, Vol.24 (1), p.11-24

2023

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Subcutaneous cardioverter defibrillator has longer time to therapy but is less cardiotoxic than transvenous cardioverter defibrillator. Study carried out in a preclinical porcine model

Europace (London, England), 2018-05, Vol.20 (5), p.873-879

2018

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Combinatorial Therapy With Tamoxifen and Trifluoperazine Effectively Inhibits Malignant Peripheral Nerve Sheath Tumor Growth by Targeting Complementary Signaling Cascades

Journal of neuropathology and experimental neurology, 2014-11, Vol.73 (11), p.1078-1090

2014

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Experimental design of preclinical experiments: number of PDX lines vs subsampling within PDX lines

Neuro-oncology (Charlottesville, Va.), 2021-12, Vol.23 (12), p.2066-2075

2021

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Biocompatibility index of antiseptic agents by parallel assessment of antimicrobial activity and cellular cytotoxicity

Journal of antimicrobial chemotherapy, 2008-06, Vol.61 (6), p.1281-1287

2008

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Answering Unanswerable Questions in the Clinical Laboratory with Data Warehouses

Clinical chemistry (Baltimore, Md.), 2019-12, Vol.65 (12), p.1471-1473

Jackups, Jr, Ronald

2019

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An Autopsy Case of Preclinical/Early Clinical Pick Disease

Journal of neuropathology and experimental neurology, 2019-10, Vol.78 (10), p.971-974

2019

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Characterization of anastrozole effects, delivered by an intravaginal ring in cynomolgus monkeys

Human reproduction (Oxford), 2015-02, Vol.30 (2), p.308-314

2015

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Selective Estrogen Receptor Modulators Differentially Regulate Alzheimer-Like Changes in Female 3xTg-AD Mice

Endocrinology (Philadelphia), 2008-05, Vol.149 (5), p.2607-2611

2008

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Test of the usefulness of a paradigm to identify potential cardiovascular liabilities of four test articles with varying pharmacological properties in anesthetized guinea pigs

Toxicological sciences, 2014-02, Vol.137 (2), p.458-468

2014

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Identification of new antimalarial drugs by linear discriminant analysis and topological virtual screening

Journal of antimicrobial chemotherapy, 2006-03, Vol.57 (3), p.489-497

2006

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Fibrinogen/thrombin-based collagen fleece (TachoComb®) promotes regeneration in pulmonary arterial injury

European journal of cardio-thoracic surgery, 2012-04, Vol.41 (4), p.926-932

2012

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Oral β-glucan reduces infarction size and improves regional contractile function in a porcine ischaemia/reperfusion model

European journal of cardio-thoracic surgery, 2012-04, Vol.41 (4), p.919-925

2012

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Development of a novel glucose polymer solution (icodextrin) for adhesion prevention: pre-clinical studies

Human reproduction (Oxford), 2000-08, Vol.15 (8), p.1764-1772

2000

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Implication of the Endocannabinoid System in the Locomotor Hyperactivity Associated with Congenital Hypothyroidism

Endocrinology (Philadelphia), 2008-05, Vol.149 (5), p.2657-2666

2008

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Evaluation of a two-phase scid mouse model preconditioned with anti-interferon-gamma monoclonal antibody for drug testing against Cryptosporidium parvum

The Journal of infectious diseases, 1995-10, Vol.172 (4), p.1160

1995

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Evaluation of the Mutagenicity and DNA-Modifying Activity of Carcinogens and Noncarcinogens in Microbial Systems

JNCI : Journal of the National Cancer Institute, 1979-04, Vol.62 (4), p.873-892

1979

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Reproducibility of Results in “Near-Replicate” Carcinogenesis Bioassays

JNCI : Journal of the National Cancer Institute, 1987-06, Vol.78 (6), p.1149-1158

1987

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Initial National Cancer Institute Studies on Mutagenesis as a Prescreen for Chemical Carcinogens: An Appraisal

JNCI : Journal of the National Cancer Institute, 1979-04, Vol.62 (4), p.919-926

1979

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In-vitro and in-vivo antimicrobial activities of a novel cephalosporin derivative, CP6162, possessing a dihydroxypyridone moiety at the C-3 side chain

Journal of antimicrobial chemotherapy, 1991-01, Vol.27 (1), p.41-53

1991

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Comparison and Evaluation of Some Experimental Designs for Use in Carcinogen Screening

JNCI : Journal of the National Cancer Institute, 1979-05, Vol.62 (5), p.1209-1219

1979

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Designing More Efficient Preclinical Experiments: A Simulation Study in Chemotherapy-Induced Myelosupression

Antisense oligonucleotide therapeutics in neurodegenerative diseases: the case of polyglutamine disorders

The frontline of alternatives to animal testing: novel in vitro skin model application in drug development and evaluation

Of mice and human embryos: is there an ethically preferred order of preclinical research on new assisted reproductive technologies?

The Role of Glia Underlying Acupuncture Analgesia in Animal Pain Models: A Systematic Review and Meta-Analysis

Subcutaneous cardioverter defibrillator has longer time to therapy but is less cardiotoxic than transvenous cardioverter defibrillator. Study carried out in a preclinical porcine model

Combinatorial Therapy With Tamoxifen and Trifluoperazine Effectively Inhibits Malignant Peripheral Nerve Sheath Tumor Growth by Targeting Complementary Signaling Cascades

Experimental design of preclinical experiments: number of PDX lines vs subsampling within PDX lines

Biocompatibility index of antiseptic agents by parallel assessment of antimicrobial activity and cellular cytotoxicity

Answering Unanswerable Questions in the Clinical Laboratory with Data Warehouses

An Autopsy Case of Preclinical/Early Clinical Pick Disease

Characterization of anastrozole effects, delivered by an intravaginal ring in cynomolgus monkeys

Selective Estrogen Receptor Modulators Differentially Regulate Alzheimer-Like Changes in Female 3xTg-AD Mice

Test of the usefulness of a paradigm to identify potential cardiovascular liabilities of four test articles with varying pharmacological properties in anesthetized guinea pigs

Identification of new antimalarial drugs by linear discriminant analysis and topological virtual screening

Fibrinogen/thrombin-based collagen fleece (TachoComb®) promotes regeneration in pulmonary arterial injury

Oral β-glucan reduces infarction size and improves regional contractile function in a porcine ischaemia/reperfusion model

Development of a novel glucose polymer solution (icodextrin) for adhesion prevention: pre-clinical studies

Implication of the Endocannabinoid System in the Locomotor Hyperactivity Associated with Congenital Hypothyroidism

Evaluation of a two-phase scid mouse model preconditioned with anti-interferon-gamma monoclonal antibody for drug testing against Cryptosporidium parvum

Evaluation of the Mutagenicity and DNA-Modifying Activity of Carcinogens and Noncarcinogens in Microbial Systems

Reproducibility of Results in “Near-Replicate” Carcinogenesis Bioassays

Initial National Cancer Institute Studies on Mutagenesis as a Prescreen for Chemical Carcinogens: An Appraisal

In-vitro and in-vivo antimicrobial activities of a novel cephalosporin derivative, CP6162, possessing a dihydroxypyridone moiety at the C-3 side chain

Comparison and Evaluation of Some Experimental Designs for Use in Carcinogen Screening

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