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Hsp27 chaperones FUS phase separation under the modulation of stress-induced phosphorylation

Nature structural & molecular biology, 2020-04, Vol.27 (4), p.363

2020

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Local unfolding of the HSP27 monomer regulates chaperone activity

Nature communications, 2019-03, Vol.10 (1), p.1068-1068, Article 1068

2019

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HspB1 and Hsc70 chaperones engage distinct tau species and have different inhibitory effects on amyloid formation

The Journal of biological chemistry, 2018-02, Vol.293 (8), p.2687-2700

2018

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Heat Shock Protein 27 Injection Leads to Caspase Activation in the Visual Pathway and Retinal T-Cell Response

International journal of molecular sciences, 2021-01, Vol.22 (2), p.513

2021

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The Chaperone Activity and Substrate Spectrum of Human Small Heat Shock Proteins

The Journal of biological chemistry, 2017-01, Vol.292 (2), p.672-684

2017

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Competing protein-protein interactions regulate binding of Hsp27 to its client protein tau

Nature communications, 2018-11, Vol.9 (1), p.4563-11, Article 4563

2018

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Hsp27 as a therapeutic target in cancers

Current drug targets, 2014-04, Vol.15 (4), p.423

2014

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Small heat shock proteins HSP27 (HspB1), αB-crystallin (HspB5) and HSP22 (HspB8) as regulators of cell death

The international journal of biochemistry & cell biology, 2012-10, Vol.44 (10), p.1622-1631

2012

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HSP27, 70 and 90, anti-apoptotic proteins, in clinical cancer therapy

International journal of oncology, 2014-07, Vol.45 (1), p.18-30

2014

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HSPB1 Enhances SIRT2-Mediated G6PD Activation and Promotes Glioma Cell Proliferation

PloS one, 2016-10, Vol.11 (10), p.e0164285-e0164285

2016

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Neuroprotection of hypoxic postconditioning against global cerebral ischemia through influencing posttranslational regulations of heat shock protein 27 in adult rats

Brain pathology (Zurich, Switzerland), 2017-11, Vol.27 (6), p.822-838

2017

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Biophysical analyses and functional implications of the interaction between Heat Shock Protein 27 and antibodies to HSP27

Biochimica et biophysica acta. General subjects, 2019-10, Vol.1863 (10), p.1536-1546

2019

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Characterization of human small heat shock protein HSPB1 α-crystallin domain localized mutants associated with hereditary motor neuron diseases

Scientific reports, 2018-01, Vol.8 (1), p.688-15, Article 688

2018

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A Dual Targeting Dendrimer-Mediated siRNA Delivery System for Effective Gene Silencing in Cancer Therapy

Journal of the American Chemical Society, 2018-11, Vol.140 (47), p.16264-16274

2018

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Knock down of heat shock protein 27 (HspB1) induces degradation of several putative client proteins

PloS one, 2012-01, Vol.7 (1), p.e29719

2012

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Promoting siRNA delivery via enhanced cellular uptake using an arginine-decorated amphiphilic dendrimer

Nanoscale, 2015-03, Vol.7 (9), p.3867-3875

2015

Volltextzugriff (PDF)

Heat Shock Proteins Promote Cancer: It's a Protection Racket

Trends in biochemical sciences (Amsterdam. Regular ed.), 2016-04, Vol.41 (4), p.311-323

2016

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Heat shock protein 27 phosphorylation: kinases, phosphatases, functions and pathology

Cellular and molecular life sciences : CMLS, 2009-10, Vol.66 (20), p.3289-3307

2009

Volltextzugriff (PDF)

Extracellular HSP27 acts as a signaling molecule to activate NF-κB in macrophages

Cell stress & chaperones, 2013-01, Vol.18 (1), p.53-63

2013

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HSPB1 as a novel regulator of ferroptotic cancer cell death

Oncogene, 2015-11, Vol.34 (45), p.5617-5625

2015

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Terminal Regions Confer Plasticity to the Tetrameric Assembly of Human HspB2 and HspB3

Journal of molecular biology, 2018-09, Vol.430 (18), p.3297-3310

2018

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Molecular Chaperones in the Pathogenesis of Amyotrophic Lateral Sclerosis: The Role of HSPB1

Human mutation, 2016-11, Vol.37 (11), p.1202-1208

2016

Volltextzugriff (PDF)

Ratio of phosphorylated HSP27 to nonphosphorylated HSP27 biphasically acts as a determinant of cellular fate in gemcitabine-resistant pancreatic cancer cells

Cellular signalling, 2015-04, Vol.27 (4), p.807-817

2015

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The effects of HSP27 against UVB-induced photoaging in rat skin

Biochemical and biophysical research communications, 2019-05, Vol.512 (3), p.435-440

2019

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HSPB1 Inhibits the Endothelial-to-Mesenchymal Transition to Suppress Pulmonary Fibrosis and Lung Tumorigenesis

Cancer research (Chicago, Ill.), 2016-03, Vol.76 (5), p.1019-1030

2016

Volltextzugriff (PDF)

1 – 25 von 2.488

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Hsp27 chaperones FUS phase separation under the modulation of stress-induced phosphorylation

Local unfolding of the HSP27 monomer regulates chaperone activity

HspB1 and Hsc70 chaperones engage distinct tau species and have different inhibitory effects on amyloid formation

Heat Shock Protein 27 Injection Leads to Caspase Activation in the Visual Pathway and Retinal T-Cell Response

The Chaperone Activity and Substrate Spectrum of Human Small Heat Shock Proteins

Competing protein-protein interactions regulate binding of Hsp27 to its client protein tau

Hsp27 as a therapeutic target in cancers

Small heat shock proteins HSP27 (HspB1), αB-crystallin (HspB5) and HSP22 (HspB8) as regulators of cell death

HSP27, 70 and 90, anti-apoptotic proteins, in clinical cancer therapy

HSPB1 Enhances SIRT2-Mediated G6PD Activation and Promotes Glioma Cell Proliferation

Neuroprotection of hypoxic postconditioning against global cerebral ischemia through influencing posttranslational regulations of heat shock protein 27 in adult rats

Biophysical analyses and functional implications of the interaction between Heat Shock Protein 27 and antibodies to HSP27

Characterization of human small heat shock protein HSPB1 α-crystallin domain localized mutants associated with hereditary motor neuron diseases

A Dual Targeting Dendrimer-Mediated siRNA Delivery System for Effective Gene Silencing in Cancer Therapy

Knock down of heat shock protein 27 (HspB1) induces degradation of several putative client proteins

Promoting siRNA delivery via enhanced cellular uptake using an arginine-decorated amphiphilic dendrimer

Heat Shock Proteins Promote Cancer: It's a Protection Racket

Heat shock protein 27 phosphorylation: kinases, phosphatases, functions and pathology

Extracellular HSP27 acts as a signaling molecule to activate NF-κB in macrophages

HSPB1 as a novel regulator of ferroptotic cancer cell death

Terminal Regions Confer Plasticity to the Tetrameric Assembly of Human HspB2 and HspB3

Molecular Chaperones in the Pathogenesis of Amyotrophic Lateral Sclerosis: The Role of HSPB1

Ratio of phosphorylated HSP27 to nonphosphorylated HSP27 biphasically acts as a determinant of cellular fate in gemcitabine-resistant pancreatic cancer cells

The effects of HSP27 against UVB-induced photoaging in rat skin

HSPB1 Inhibits the Endothelial-to-Mesenchymal Transition to Suppress Pulmonary Fibrosis and Lung Tumorigenesis

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