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HPMA Copolymer Conjugates of Paclitaxel and Docetaxel with pH-Controlled Drug Release

Molecular pharmaceutics, 2010-08, Vol.7 (4), p.1015-1026

2010

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Bloodstream Stability Predetermines the Antitumor Efficacy of Micellar Polymer–Doxorubicin Drug Conjugates with pH-Triggered Drug Release

Molecular pharmaceutics, 2018-09, Vol.15 (9), p.3654-3663

2018

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Simultaneous Delivery of Doxorubicin and Protease Inhibitor Derivative to Solid Tumors via Star-Shaped Polymer Nanomedicines Overcomes P‑gp- and STAT3-Mediated Chemoresistance

Biomacromolecules, 2022-06, Vol.23 (6), p.2522-2535

2022

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Polymer donors of nitric oxide improve the treatment of experimental solid tumours with nanosized polymer therapeutics

Journal of drug targeting, 2017-11, Vol.25 (9-10), p.796-808

2017

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HPMA copolymer-doxorubicin conjugates: The effects of molecular weight and architecture on biodistribution and in vivo activity

Journal of controlled release, 2012-12, Vol.164 (3), p.346-354

2012

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Dimerization of an Immunoactivating Peptide Derived from Mycobacterial hsp65 Using N‑Hydroxysuccinimide Based Bifunctional Reagents Is Critical for Its Antitumor Properties

Bioconjugate chemistry, 2012-10, Vol.23 (10), p.2032-2041

2012

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Dimerization of an Immunoactivating Peptide Derived from Mycobacterial hsp65 Using N‑Hydroxysuccinimide Based Bifunctional Reagents Is Critical for Its Antitumor Properties

Bioconjugate chemistry, 2014-02, Vol.25 (2), p.451-451

2014

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Tumor-targeted micelle-forming block copolymers for overcoming of multidrug resistance

Journal of controlled release, 2017-01, Vol.245, p.41-51

2017

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Polymer nanomedicines based on micelle-forming amphiphilic or water-soluble polymer-doxorubicin conjugates: Comparative study of in vitro and in vivo properties related to the polymer carrier structure, composition, and hydrodynamic properties

Journal of controlled release, 2020-05, Vol.321, p.718-733

2020

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Glycopolymers Decorated with 3- O -Substituted Thiodigalactosides as Potent Multivalent Inhibitors of Galectin-3

Journal of medicinal chemistry, 2022-03, Vol.65 (5), p.3866-3878

2022

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Conjugates of doxorubicin with graft HPMA copolymers for passive tumor targeting

Journal of controlled release, 2008-12, Vol.132 (3), p.184-192

2008

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Metastatic spread inhibition of cancer cells through stimuli-sensitive HPMA copolymer-bound actinonin nanomedicines

Nanomedicine, 2022-08, Vol.44, p.102578-102578, Article 102578

2022

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Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling

Journal of controlled release, 2021-04, Vol.332, p.563-580

2021

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Polymer donors of nitric oxide for enhanced accumulation of anticancer agents in solid tumors

Journal of controlled release, 2017-08, Vol.259, p.e91-e91

2017

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HPMA-Based Copolymers Carrying STAT3 Inhibitor Cucurbitacin-D as Stimulus-Sensitive Nanomedicines for Oncotherapy

Pharmaceutics, 2021-01, Vol.13 (2), p.179

2021

Volltextzugriff (PDF)

Micelle-Forming Block Copolymers Tailored for Inhibition of P-gp-Mediated Multidrug Resistance: Structure to Activity Relationship

Pharmaceutics, 2019-11, Vol.11 (11), p.579

2019

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Properties of HPMA copolymer–doxorubicin conjugates with pH-controlled activation: Effect of polymer chain modification

Journal of controlled release, 2006-09, Vol.115 (1), p.26-36

2006

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SOT101 induces NK cell cytotoxicity and potentiates antibody-dependent cell cytotoxicity and anti-tumor activity

Frontiers in immunology, 2022-10, Vol.13, p.989895-989895

2022

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1087 SOT201 is a novel cis-acting immunocytokine targeting IL-15Rβγ to reinvigorate PD-1+tumor infiltrating lymphocytes and potentiate anti-tumor efficacy

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1196-A1196

2023

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Immunocompatibility evaluation of hydrogel-coated polyimide implants for applications in regenerative medicine

Journal of biomedical materials research. Part A, 2014-06, Vol.102 (6), p.1982-1990

2014

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Drug-HPMA-HuIg conjugates effective against human solid cancer

Advances in experimental medicine and biology, 2003, Vol.519, p.125

2003

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Preclinical Evaluation of Linear HPMA-Doxorubicin Conjugates with pH-Sensitive Drug Release: Efficacy, Safety, and Immunomodulating Activity in Murine Model

Pharmaceutical research, 2010, Vol.27 (1), p.200-208

2010

Volltextzugriff (PDF)

Antitumor activity of IL‐2/anti‐IL‐2 mAb immunocomplexes exerts synergism with that of N‐(2‐hydroxypropyl)methacrylamide copolymer‐bound doxorubicin conjugate due to its low immunosuppressive activity

International journal of cancer, 2011-10, Vol.129 (8), p.2002-2012

2011

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Implantation of ultrathin, biofunctionalized polyimide membranes into the subretinal space of rats

Biomaterials, 2011-06, Vol.32 (16), p.3890-3898

2011

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Chemotherapy based on HPMA copolymer conjugates with pH-controlled release of doxorubicin triggers anti-tumor immunity

Journal of controlled release, 2005-12, Vol.110 (1), p.119-129

2005

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HPMA Copolymer Conjugates of Paclitaxel and Docetaxel with pH-Controlled Drug Release

Bloodstream Stability Predetermines the Antitumor Efficacy of Micellar Polymer–Doxorubicin Drug Conjugates with pH-Triggered Drug Release

Simultaneous Delivery of Doxorubicin and Protease Inhibitor Derivative to Solid Tumors via Star-Shaped Polymer Nanomedicines Overcomes P‑gp- and STAT3-Mediated Chemoresistance

Polymer donors of nitric oxide improve the treatment of experimental solid tumours with nanosized polymer therapeutics

HPMA copolymer-doxorubicin conjugates: The effects of molecular weight and architecture on biodistribution and in vivo activity

Dimerization of an Immunoactivating Peptide Derived from Mycobacterial hsp65 Using N‑Hydroxysuccinimide Based Bifunctional Reagents Is Critical for Its Antitumor Properties

Dimerization of an Immunoactivating Peptide Derived from Mycobacterial hsp65 Using N‑Hydroxysuccinimide Based Bifunctional Reagents Is Critical for Its Antitumor Properties

Tumor-targeted micelle-forming block copolymers for overcoming of multidrug resistance

Polymer nanomedicines based on micelle-forming amphiphilic or water-soluble polymer-doxorubicin conjugates: Comparative study of in vitro and in vivo properties related to the polymer carrier structure, composition, and hydrodynamic properties

Glycopolymers Decorated with 3- O -Substituted Thiodigalactosides as Potent Multivalent Inhibitors of Galectin-3

Conjugates of doxorubicin with graft HPMA copolymers for passive tumor targeting

Metastatic spread inhibition of cancer cells through stimuli-sensitive HPMA copolymer-bound actinonin nanomedicines

Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling

Polymer donors of nitric oxide for enhanced accumulation of anticancer agents in solid tumors

HPMA-Based Copolymers Carrying STAT3 Inhibitor Cucurbitacin-D as Stimulus-Sensitive Nanomedicines for Oncotherapy

Micelle-Forming Block Copolymers Tailored for Inhibition of P-gp-Mediated Multidrug Resistance: Structure to Activity Relationship

Properties of HPMA copolymer–doxorubicin conjugates with pH-controlled activation: Effect of polymer chain modification

SOT101 induces NK cell cytotoxicity and potentiates antibody-dependent cell cytotoxicity and anti-tumor activity

1087 SOT201 is a novel cis-acting immunocytokine targeting IL-15Rβγ to reinvigorate PD-1+tumor infiltrating lymphocytes and potentiate anti-tumor efficacy

Immunocompatibility evaluation of hydrogel-coated polyimide implants for applications in regenerative medicine

Drug-HPMA-HuIg conjugates effective against human solid cancer

Preclinical Evaluation of Linear HPMA-Doxorubicin Conjugates with pH-Sensitive Drug Release: Efficacy, Safety, and Immunomodulating Activity in Murine Model

Antitumor activity of IL‐2/anti‐IL‐2 mAb immunocomplexes exerts synergism with that of N‐(2‐hydroxypropyl)methacrylamide copolymer‐bound doxorubicin conjugate due to its low immunosuppressive activity

Implantation of ultrathin, biofunctionalized polyimide membranes into the subretinal space of rats

Chemotherapy based on HPMA copolymer conjugates with pH-controlled release of doxorubicin triggers anti-tumor immunity

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