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A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects

Nucleic acids research, 2010-09, Vol.38 (17), p.5761

2010

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The ribosome assembly factor Nep1 responsible for Bowen-Conradi syndrome is a pseudouridine-N1-specific methyltransferase

Nucleic acids research, 2010-04, Vol.38 (7), p.2387

2010

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Influence of a fluorobenzene nucleobase analogue on the conformational flexibility of RNA studied by molecular dynamics simulations

Nucleic acids research, 2004-01, Vol.32 (21), p.6304

2004

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6-Oxocytidine a novel protonated C-base analogue for stable triple helix formation

Nucleic acids research, 1995-09, Vol.23 (17), p.3465-3472

1995

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Synthesis and selective cleavage of an oligodeoxynucleotide containing a bridged internucleotide 5'-phosphorothioate linkage

Nucleic acids research, 1991-04, Vol.19 (7), p.1437-1441

1991

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Synthesis and selective cleavage of oligodeoxyribonucleotides containing non-chiral internucleotide phosphoramidate linkages

Nucleic acids research, 1989-08, Vol.17 (15), p.5973-5988

1989

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Synthesis and structure assignments of amide protected nucleosides and their use as phosphoramidites in deoxyoligonucleotide synthesis

Nucleic acids research, 1988-04, Vol.16 (8), p.3525-3543

1988

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High Resolution Structure and Double Electron-Electron Resonance of the Zebrafish Voltage-dependent Anion Channel 2 Reveal an Oligomeric Population

The Journal of biological chemistry, 2014-05, Vol.289 (18), p.12566-12577

2014

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HERG Potassium Channel Activation Is Shifted by Phorbol Esters via Protein Kinase A-dependent Pathways

The Journal of biological chemistry, 1998-09, Vol.273 (39), p.25285-25291

1998

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Ultraviolet-B Radiation Effects on the Structure and Function of Lower Trophic Levels of the Marine Planktonic Food Web

Photochemistry and photobiology, 2006-07, Vol.82 (4), p.887-897

2006

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Discovery and characterization of small-molecule inhibitors of NLRP3 and NLRC4 inflammasomes

The Journal of biological chemistry, 2021-01, Vol.296, p.100597-100597, Article 100597

2021

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Asbestos-induced Disruption of Calcium Homeostasis Induces Endoplasmic Reticulum Stress in Macrophages

The Journal of biological chemistry, 2014-11, Vol.289 (48), p.33391-33403

2014

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Modulation of the Mevalonate Pathway by Akt Regulates Macrophage Survival and Development of Pulmonary Fibrosis

The Journal of biological chemistry, 2014-12, Vol.289 (52), p.36204-36219

2014

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The Residue Mass of L-Pyrrolysine in Three Distinct Methylamine Methyltransferases

The Journal of biological chemistry, 2005-11, Vol.280 (44), p.36962-36969

2005

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Coexistence of Group I and Group II Chaperonins in the Archaeon Methanosarcina mazei

The Journal of biological chemistry, 2003-08, Vol.278 (35), p.33256-33267

2003

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Thermoadaptation trait revealed by the genome sequence of thermophilic Geobacillus kaustophilus

Nucleic acids research, 2004-01, Vol.32 (21), p.6292

2004

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Point Mutations Throughout the GLI3 Gene Cause Greig Cephalopolysyndactyly Syndrome

Human molecular genetics, 1999-09, Vol.8 (9), p.1769-1777

1999

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Functional Analysis of Multiple Single-stranded DNA-binding Proteins from Methanosarcina acetivorans and Their Effects on DNA Synthesis by DNA Polymerase BI

The Journal of biological chemistry, 2004-02, Vol.279 (8), p.6315-6326

2004

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Biochemical and Mutational Analyses of a Unique Clamp Loader Complex in the Archaeon Methanosarcina acetivorans

The Journal of biological chemistry, 2005-12, Vol.280 (51), p.41852-41863

2005

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RamA, a Protein Required for Reductive Activation of Corrinoid-dependent Methylamine Methyltransferase Reactions in Methanogenic Archaea

The Journal of biological chemistry, 2009-01, Vol.284 (4), p.2285-2295

2009

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Foundations for blockbuster drugs in federally sponsored research

The FASEB journal, 2001-08, Vol.15 (10), p.1671-1676

THOMPSON, RICHARD B.

2001

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Subunit Interaction and Regulation of Activity through Terminal Domains of the Family D DNA Polymerase from Pyrococcus horikoshii

The Journal of biological chemistry, 2003-06, Vol.278 (23), p.21247-21257

2003

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Understanding the chemical mechanisms of life

Nature chemical biology, 2007-12, Vol.3 (12), p.745-749

2007

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A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity

A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects

The ribosome assembly factor Nep1 responsible for Bowen-Conradi syndrome is a pseudouridine-N1-specific methyltransferase

Influence of a fluorobenzene nucleobase analogue on the conformational flexibility of RNA studied by molecular dynamics simulations

6-Oxocytidine a novel protonated C-base analogue for stable triple helix formation

Synthesis and selective cleavage of an oligodeoxynucleotide containing a bridged internucleotide 5'-phosphorothioate linkage

Synthesis and selective cleavage of oligodeoxyribonucleotides containing non-chiral internucleotide phosphoramidate linkages

Synthesis and structure assignments of amide protected nucleosides and their use as phosphoramidites in deoxyoligonucleotide synthesis

High Resolution Structure and Double Electron-Electron Resonance of the Zebrafish Voltage-dependent Anion Channel 2 Reveal an Oligomeric Population

HERG Potassium Channel Activation Is Shifted by Phorbol Esters via Protein Kinase A-dependent Pathways

Ultraviolet-B Radiation Effects on the Structure and Function of Lower Trophic Levels of the Marine Planktonic Food Web

Discovery and characterization of small-molecule inhibitors of NLRP3 and NLRC4 inflammasomes

Asbestos-induced Disruption of Calcium Homeostasis Induces Endoplasmic Reticulum Stress in Macrophages

Modulation of the Mevalonate Pathway by Akt Regulates Macrophage Survival and Development of Pulmonary Fibrosis

The Residue Mass of L-Pyrrolysine in Three Distinct Methylamine Methyltransferases

Coexistence of Group I and Group II Chaperonins in the Archaeon Methanosarcina mazei

Thermoadaptation trait revealed by the genome sequence of thermophilic Geobacillus kaustophilus

Point Mutations Throughout the GLI3 Gene Cause Greig Cephalopolysyndactyly Syndrome

Functional Analysis of Multiple Single-stranded DNA-binding Proteins from Methanosarcina acetivorans and Their Effects on DNA Synthesis by DNA Polymerase BI

Biochemical and Mutational Analyses of a Unique Clamp Loader Complex in the Archaeon Methanosarcina acetivorans

RamA, a Protein Required for Reductive Activation of Corrinoid-dependent Methylamine Methyltransferase Reactions in Methanogenic Archaea

Foundations for blockbuster drugs in federally sponsored research

Subunit Interaction and Regulation of Activity through Terminal Domains of the Family D DNA Polymerase from Pyrococcus horikoshii

Understanding the chemical mechanisms of life

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