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Cross-Linking of the Extracellular Matrix by the Maillard Reaction in Aging and Diabetes: An Update on "a Puzzle Nearing Resolution"

Annals of the New York Academy of Sciences, 2005-06, Vol.1043 (1), p.533-544

2005

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Glucosepane is a major protein cross-link of the senescent human extracellular matrix. Relationship with diabetes

The Journal of biological chemistry, 2005-04, Vol.280 (13), p.12310-12315

2005

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Paradoxical effects of green tea (Camellia sinensis) and antioxidant vitamins in diabetic rats: Improved retinopathy and renal mitochondrial defects but deterioration of collagen matrix glycoxidation and cross-linking

Diabetes (New York, N.Y.), 2005-02, Vol.54 (2), p.517-526

2005

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Effect of pyridoxamine on chemical modification of proteins by carbonyls in diabetic rats: characterization of a major product from the reaction of pyridoxamine and methylglyoxal

Archives of biochemistry and biophysics, 2002-06, Vol.402 (1), p.110-119

2002

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Unexpected Carbonyl Mobility in Aminoketoses: The Key to Major Maillard Crosslinks

Angewandte Chemie International Edition, 2002-03, Vol.41 (5), p.801-804

2002

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Site-Specific Quantitative Evaluation of the Protein Glycation Product N 6-(2,3-Dihydroxy-5,6-dioxohexyl)-l-lysinate by LC−(ESI)MS Peptide Mapping: Evidence for Its Key Role in AGE Formation

Bioconjugate chemistry, 2003-05, Vol.14 (3), p.619-628

2003

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Pyridinium-carbaldehyde: active Maillard reaction product from the reaction of hexoses with lysine residues

Carbohydrate research, 2004-02, Vol.339 (3), p.705-714

2004

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Site-Specific Quantitative Evaluation of the Protein Glycation Product N6-(2,3-Dihydroxy-5,6-dioxohexyl)-l-lysinate by LC−(ESI)MS Peptide Mapping: Evidence for Its Key Role in AGE Formation

Bioconjugate chemistry, 2003-05, Vol.14 (3), p.619-628

2003

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Spiro Cross-Links: Representatives of a New Class of Glycoxidation Products

Journal of agricultural and food chemistry, 2003-07, Vol.51 (16), p.4810-4818

2003

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Identification and quantification of major maillard cross-links in human serum albumin and lens protein. Evidence for glucosepane as the dominant compound

The Journal of biological chemistry, 2002-07, Vol.277 (28), p.24907-24915

2002

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Synthesis and Evaluation of Heteroaryl-Substituted Dihydronaphthalenes and Indenes: Potent and Selective Inhibitors of Aldosterone Synthase (CYP11B2) for the Treatment of Congestive Heart Failure and Myocardial Fibrosis

Journal of medicinal chemistry, 2006-04, Vol.49 (7), p.2222-2231

2006

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Formation pathways for lysine-arginine cross-links derived from hexoses and pentoses by Maillard processes: unraveling the structure of a pentosidine precursor

The Journal of biological chemistry, 2001-06, Vol.276 (26), p.23405-23412

2001

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Heteroaryl-Substituted Naphthalenes and Structurally Modified Derivatives: Selective Inhibitors of CYP11B2 for the Treatment of Congestive Heart Failure and Myocardial Fibrosis

Journal of medicinal chemistry, 2005-10, Vol.48 (21), p.6632-6642

2005

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Glucosepane Is a Major Protein Cross-link of the Senescent Human Extracellular Matrix

The Journal of biological chemistry, 2005-04, Vol.280 (13), p.12310-12315

2005

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Identification and Quantification of Major Maillard Cross-links in Human Serum Albumin and Lens Protein

The Journal of biological chemistry, 2002-07, Vol.277 (28), p.24907-24915

2002

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Paradoxical Effects of Green Tea (Camellia Sinensis) and Antioxidant Vitamins in Diabetic Rats

Diabetes (New York, N.Y.), 2005-02, Vol.54 (2), p.517-526

2005

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Serum-free culture of primary human hepatocytes in a miniaturized hollow-fibre membrane bioreactor for pharmacological in vitro studies: Serum-free culture of primary human hepatocyte bioreactor

Journal of tissue engineering and regenerative medicine, 2015-09, Vol.9 (9), p.1017-1026

2015

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Formation pathways for lysine–arginine cross-links derived from hexoses and pentoses by Maillard processes

International Congress series, 2002-11, Vol.1245, p.255-261

2002

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Formation Pathways for Lysine-Arginine Cross-links Derived from Hexoses and Pentoses by Maillard Processes

The Journal of biological chemistry, 2001-06, Vol.276 (26), p.23405-23412

2001

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Novel 5α-Reductase Inhibitors: Synthesis, Structure−Activity Studies, and Pharmacokinetic Profile of Phenoxybenzoylphenyl Acetic Acids

Journal of medicinal chemistry, 2006-01, Vol.49 (2), p.748-759

2006

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Novel 5alpha-reductase inhibitors: synthesis, structure-activity studies, and pharmacokinetic profile of phenoxybenzoylphenyl acetic acids

Journal of medicinal chemistry, 2006-01, Vol.49 (2), p.748-759

2006

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Unexpected Carbonyl Mobility in Aminoketoses: The Key to Major Maillard Crosslinks This work was supported by the Deutsche Forschungsgemeinschaft. We are grateful to S. Reeb, Institute of Chemistry, University of Hohenheim, as well as J. Rebell, Institute of Organic Chemistry, University of Stuttgart, for recording the NMR spectra

Angewandte Chemie International Edition, 2002-03, Vol.41 (5), p.801

2002

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Unerwartete Carbonyl-Mobilität in Aminoketosen: der Schlüssel zu wichtigen Maillard-Quervernetzungsprodukten

Angewandte Chemie, 2002-03, Vol.114 (5), p.826-828

2002

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Green Tea (Camellia sinensis) Ameliorates Retinopathy and Renal Mitochondrial Defects but Deteriorates Collagen Glycoxidation and Cross-Linking in Experimental Diabetes

Annals of the New York Academy of Sciences, 2005-06, Vol.1043 (1), p.940-940

2005

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Unerwartete Carbonyl‐Mobilität in Aminoketosen: der Schlüssel zu wichtigen Maillard‐Quervernetzungsprodukten

Angewandte Chemie, 2002-03, Vol.114 (5), p.826-828

2002

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Cross-Linking of the Extracellular Matrix by the Maillard Reaction in Aging and Diabetes: An Update on "a Puzzle Nearing Resolution"

Glucosepane is a major protein cross-link of the senescent human extracellular matrix. Relationship with diabetes

Paradoxical effects of green tea (Camellia sinensis) and antioxidant vitamins in diabetic rats: Improved retinopathy and renal mitochondrial defects but deterioration of collagen matrix glycoxidation and cross-linking

Effect of pyridoxamine on chemical modification of proteins by carbonyls in diabetic rats: characterization of a major product from the reaction of pyridoxamine and methylglyoxal

Unexpected Carbonyl Mobility in Aminoketoses: The Key to Major Maillard Crosslinks

Site-Specific Quantitative Evaluation of the Protein Glycation Product N 6-(2,3-Dihydroxy-5,6-dioxohexyl)-l-lysinate by LC−(ESI)MS Peptide Mapping: Evidence for Its Key Role in AGE Formation

Pyridinium-carbaldehyde: active Maillard reaction product from the reaction of hexoses with lysine residues

Site-Specific Quantitative Evaluation of the Protein Glycation Product N6-(2,3-Dihydroxy-5,6-dioxohexyl)-l-lysinate by LC−(ESI)MS Peptide Mapping: Evidence for Its Key Role in AGE Formation

Spiro Cross-Links: Representatives of a New Class of Glycoxidation Products

Identification and quantification of major maillard cross-links in human serum albumin and lens protein. Evidence for glucosepane as the dominant compound

Synthesis and Evaluation of Heteroaryl-Substituted Dihydronaphthalenes and Indenes: Potent and Selective Inhibitors of Aldosterone Synthase (CYP11B2) for the Treatment of Congestive Heart Failure and Myocardial Fibrosis

Formation pathways for lysine-arginine cross-links derived from hexoses and pentoses by Maillard processes: unraveling the structure of a pentosidine precursor

Heteroaryl-Substituted Naphthalenes and Structurally Modified Derivatives: Selective Inhibitors of CYP11B2 for the Treatment of Congestive Heart Failure and Myocardial Fibrosis

Glucosepane Is a Major Protein Cross-link of the Senescent Human Extracellular Matrix

Identification and Quantification of Major Maillard Cross-links in Human Serum Albumin and Lens Protein

Paradoxical Effects of Green Tea (Camellia Sinensis) and Antioxidant Vitamins in Diabetic Rats

Serum-free culture of primary human hepatocytes in a miniaturized hollow-fibre membrane bioreactor for pharmacological in vitro studies: Serum-free culture of primary human hepatocyte bioreactor

Formation pathways for lysine–arginine cross-links derived from hexoses and pentoses by Maillard processes

Formation Pathways for Lysine-Arginine Cross-links Derived from Hexoses and Pentoses by Maillard Processes

Novel 5α-Reductase Inhibitors: Synthesis, Structure−Activity Studies, and Pharmacokinetic Profile of Phenoxybenzoylphenyl Acetic Acids

Novel 5alpha-reductase inhibitors: synthesis, structure-activity studies, and pharmacokinetic profile of phenoxybenzoylphenyl acetic acids

Unerwartete Carbonyl-Mobilität in Aminoketosen: der Schlüssel zu wichtigen Maillard-Quervernetzungsprodukten

Green Tea (Camellia sinensis) Ameliorates Retinopathy and Renal Mitochondrial Defects but Deteriorates Collagen Glycoxidation and Cross-Linking in Experimental Diabetes

Unerwartete Carbonyl‐Mobilität in Aminoketosen: der Schlüssel zu wichtigen Maillard‐Quervernetzungsprodukten

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