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The role of glutathione reductase and related enzymes on cellular redox homoeostasis network

Free radical biology & medicine, 2016-06, Vol.95, p.27-42

2016

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Glutathione reductase mediates drug resistance in glioblastoma cells by regulating redox homeostasis

Journal of neurochemistry, 2018-01, Vol.144 (1), p.93-104

2018

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Redox-mediated kick-start of mitochondrial energy metabolism drives resource-efficient seed germination

Proceedings of the National Academy of Sciences - PNAS, 2020-01, Vol.117 (1), p.741-751

2020

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Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes

Biochimica et biophysica acta, 2013-05, Vol.1830 (5), p.3217-3266

Deponte, Marcel

2013

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Klotho Deficiency Causes Heart Aging via Impairing the Nrf2-GR Pathway

Circulation research, 2021-02, Vol.128 (4), p.492-507

2021

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NADPH-dependent thioredoxin system constitutes a functional backup for cytosolic glutathione reductase in Arabidopsis

Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (22), p.9109-9114

2009

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Chloroplasts require glutathione reductase to balance reactive oxygen species and maintain efficient photosynthesis

The Plant journal : for cell and molecular biology, 2020-08, Vol.103 (3), p.1140-1154

2020

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SLC27A5 promotes sorafenib-induced ferroptosis in hepatocellular carcinoma by downregulating glutathione reductase

Cell death & disease, 2023-01, Vol.14 (1), p.22-22, Article 22

2023

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Differential molecular response of monodehydroascorbate reductase and glutathione reductase by nitration and S-nitrosylation

Journal of experimental botany, 2015-09, Vol.66 (19), p.5983-5996

2015

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Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress

Free radical biology & medicine, 2009-02, Vol.46 (4), p.443-453

2009

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New Schiff bases with a 2,6-bis(2-aminophenylthio)pyridine moiety acting as glutathione reductase activator and inhibitors: Synthesis and molecular docking studies

Journal of molecular structure, 2022-04, Vol.1254, p.132299, Article 132299

2022

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The Proto-oncometabolite Fumarate Binds Glutathione to Amplify ROS-Dependent Signaling

Molecular cell, 2013-07, Vol.51 (2), p.236-248

2013

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Transnitrosylation Mediated by the Non-canonical Catalase ROG1 Regulates Nitric Oxide Signaling in Plants

Developmental cell, 2020-05, Vol.53 (4), p.444-457.e5

2020

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Exploration of glutathione reductase for abiotic stress response in bread wheat (Triticum aestivum L.)

Plant cell reports, 2022-03, Vol.41 (3), p.639-654

2022

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Antitumor Action of Amygdalin on Human Breast Cancer Cells by Selective Sensitization to Oxidative Stress

Nutrition and cancer, 2019-04, Vol.71 (3), p.483-490

2019

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High level of reduced glutathione contributes to detoxification of lipid peroxide‐derived reactive carbonyl species in transgenic Arabidopsis overexpressing glutathione reductase under aluminum stress

Physiologia plantarum, 2017-10, Vol.161 (2), p.211-223

2017

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Evidence of a significant role of glutathione reductase in the sulfur assimilation pathway

The Plant journal : for cell and molecular biology, 2020-04, Vol.102 (2), p.246-261

2020

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Redox perturbations in yeast cells lacking glutathione reductase

Fungal genetics and biology, 2023-06, Vol.167, p.103810-103810, Article 103810

2023

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Analysis of the interaction of antimalarial agents with Plasmodium falciparum glutathione reductase through molecular mechanical calculations

Journal of molecular modeling, 2024-06, Vol.30 (6), p.181-181, Article 181

2024

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Overexpression of tomato glutathione reductase (SlGR) in transgenic tobacco enhances salt tolerance involving the S-nitrosylation of GR

Plant physiology and biochemistry, 2023-03, Vol.196, p.497-506

2023

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Increased reactive oxygen species production during reductive stress: The roles of mitochondrial glutathione and thioredoxin reductases

Biochimica et biophysica acta, 2015-06, Vol.1847 (6-7), p.514-525

2015

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An in vivo and in vitro comparison of the effects of amoxicillin, gentamicin, and cefazolin sodium antibiotics on the mouse hepatic and renal glutathione reductase enzyme

Journal of biochemical and molecular toxicology, 2020-07, Vol.34 (7), p.e22496-n/a

2020

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Improving Regulation of Enzymatic and Non-Enzymatic Antioxidants and Stress-Related Gene Stimulation in Cucumber mosaic cucumovirus -Infected Cucumber Plants Treated with Glycine Betaine, Chitosan and Combination

Molecules (Basel, Switzerland), 2020-05, Vol.25 (10), p.2341

2020

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Glutathione reductase: A cytoplasmic antioxidant enzyme and a potential target for phenothiazinium dyes in Neospora caninum

International journal of biological macromolecules, 2021-09, Vol.187, p.964-975

2021

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TrxR1, Gsr, and oxidative stress determine hepatocellular carcinoma malignancy

Proceedings of the National Academy of Sciences - PNAS, 2019-06, Vol.116 (23), p.11408-11417

2019

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The role of glutathione reductase and related enzymes on cellular redox homoeostasis network

Glutathione reductase mediates drug resistance in glioblastoma cells by regulating redox homeostasis

Redox-mediated kick-start of mitochondrial energy metabolism drives resource-efficient seed germination

Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes

Klotho Deficiency Causes Heart Aging via Impairing the Nrf2-GR Pathway

NADPH-dependent thioredoxin system constitutes a functional backup for cytosolic glutathione reductase in Arabidopsis

Chloroplasts require glutathione reductase to balance reactive oxygen species and maintain efficient photosynthesis

SLC27A5 promotes sorafenib-induced ferroptosis in hepatocellular carcinoma by downregulating glutathione reductase

Differential molecular response of monodehydroascorbate reductase and glutathione reductase by nitration and S-nitrosylation

Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress

New Schiff bases with a 2,6-bis(2-aminophenylthio)pyridine moiety acting as glutathione reductase activator and inhibitors: Synthesis and molecular docking studies

The Proto-oncometabolite Fumarate Binds Glutathione to Amplify ROS-Dependent Signaling

Transnitrosylation Mediated by the Non-canonical Catalase ROG1 Regulates Nitric Oxide Signaling in Plants

Exploration of glutathione reductase for abiotic stress response in bread wheat (Triticum aestivum L.)

Antitumor Action of Amygdalin on Human Breast Cancer Cells by Selective Sensitization to Oxidative Stress

High level of reduced glutathione contributes to detoxification of lipid peroxide‐derived reactive carbonyl species in transgenic Arabidopsis overexpressing glutathione reductase under aluminum stress

Evidence of a significant role of glutathione reductase in the sulfur assimilation pathway

Redox perturbations in yeast cells lacking glutathione reductase

Analysis of the interaction of antimalarial agents with Plasmodium falciparum glutathione reductase through molecular mechanical calculations

Overexpression of tomato glutathione reductase (SlGR) in transgenic tobacco enhances salt tolerance involving the S-nitrosylation of GR

Increased reactive oxygen species production during reductive stress: The roles of mitochondrial glutathione and thioredoxin reductases

An in vivo and in vitro comparison of the effects of amoxicillin, gentamicin, and cefazolin sodium antibiotics on the mouse hepatic and renal glutathione reductase enzyme

Improving Regulation of Enzymatic and Non-Enzymatic Antioxidants and Stress-Related Gene Stimulation in Cucumber mosaic cucumovirus -Infected Cucumber Plants Treated with Glycine Betaine, Chitosan and Combination

Glutathione reductase: A cytoplasmic antioxidant enzyme and a potential target for phenothiazinium dyes in Neospora caninum

TrxR1, Gsr, and oxidative stress determine hepatocellular carcinoma malignancy

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