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Lipocalin-2: Structure, function, distribution and role in metabolic disorders

Biomedicine & pharmacotherapy, 2021-10, Vol.142, p.112002-112002, Article 112002

2021

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Lipocalin 2: An Emerging Player in Iron Homeostasis and Inflammation

Annual review of nutrition, 2017-08, Vol.37 (1), p.103-130

2017

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Machine learning guided aptamer refinement and discovery

Nature communications, 2021-04, Vol.12 (1), p.2366-2366, Article 2366

2021

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Siderophores in Iron Metabolism: From Mechanism to Therapy Potential

Trends in molecular medicine, 2016-12, Vol.22 (12), p.1077-1090

2016

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Lipocalin-2 as a therapeutic target for brain injury: An astrocentric perspective

Progress in neurobiology, 2016-09, Vol.144, p.158-172

Suk, Kyoungho

2016

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A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis

Nature communications, 2021-12, Vol.12 (1), p.7333-17, Article 7333

2021

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Lipocalin-2: A Master Mediator of Intestinal and Metabolic Inflammation

Trends in endocrinology and metabolism, 2017-05, Vol.28 (5), p.388-397

2017

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NUPR1 is a critical repressor of ferroptosis

Nature communications, 2021-01, Vol.12 (1), p.647-647, Article 647

2021

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Gene interfered-ferroptosis therapy for cancers

Nature communications, 2021-09, Vol.12 (1), p.5311-16, Article 5311

2021

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Astrocyte‐derived lipocalin‐2 mediates hippocampal damage and cognitive deficits in experimental models of vascular dementia

Glia, 2017-09, Vol.65 (9), p.1471-1490

2017

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The novel STING antagonist H151 ameliorates cisplatin-induced acute kidney injury and mitochondrial dysfunction

American journal of physiology. Renal physiology, 2021-04, Vol.320 (4), p.F608-F616

2021

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Astrocytic phagocytosis contributes to demyelination after focal cortical ischemia in mice

Nature communications, 2022-03, Vol.13 (1), p.1134-1134, Article 1134

2022

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C/EBPδ Mediates Immunity to Renal Autoinflammatory Disorders in a Stage-specific Manner

The Journal of immunology (1950), 2024-09, Vol.213 (6), p.767-778

2024

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Functions and regulation of lipocalin-2 in gut-origin sepsis: a narrative review

Critical care (London, England), 2019-08, Vol.23 (1), p.269-269, Article 269

2019

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TNFα-induced NLRP3 inflammasome mediates adipocyte dysfunction and activates macrophages through adipocyte-derived lipocalin 2

Metabolism, clinical and experimental, 2023-05, Vol.142, p.155527-155527, Article 155527

2023

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Increased neutrophil gelatinase-associated lipocalin (NGAL) promotes airway remodelling in chronic obstructive pulmonary disease

Clinical science (1979), 2017-06, Vol.131 (11), p.1147-1159

2017

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Emerging insights into Lipocalin-2: Unraveling its role in Parkinson's Disease

Biomedicine & pharmacotherapy, 2024-08, Vol.177, p.116947, Article 116947

2024

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Neutralization of Lipocalin-2 Diminishes Stroke-Reperfusion Injury

International journal of molecular sciences, 2020-08, Vol.21 (17), p.6253

2020

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Reduced secretion of LCN2 (lipocalin 2) from reactive astrocytes through autophagic and proteasomal regulation alleviates inflammatory stress and neuronal damage

Autophagy, 2023-08, Vol.19 (8), p.2296-2317

2023

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Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment

Cancer research (Chicago, Ill.), 2017-05, Vol.77 (10), p.2647-2660

2017

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Lipocalin‐2 (NGAL) Attenuates Autophagy to Exacerbate Cardiac Apoptosis Induced by Myocardial Ischemia

Journal of cellular physiology, 2017-08, Vol.232 (8), p.2125-2134

2017

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Lipocalin-2 deficiency or blockade protects against aortic abdominal aneurysm development in mice

Cardiovascular research, 2016-08, Vol.111 (3), p.262-273

2016

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Lipocalin-2 inhibition alleviates neural injury by microglia ferroptosis suppression after experimental intracerebral hemorrhage in mice via enhancing ferritin light chain expression

Biochimica et biophysica acta. Molecular basis of disease, 2024-10, Vol.1870 (7), p.167435, Article 167435

2024

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NGAL as a Potential Target in Tumor Microenvironment

International journal of molecular sciences, 2021-11, Vol.22 (22), p.12333

2021

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Neutrophil Gelatinase-Associated Lipocalin From Macrophages Plays a Critical Role in Renal Fibrosis Via the CCL5 (Chemokine Ligand 5)-Th2 Cells-IL4 (Interleukin 4) Pathway

Hypertension (Dallas, Tex. 1979), 2022-02, Vol.79 (2), p.352-364

2022

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Lipocalin-2: Structure, function, distribution and role in metabolic disorders

Lipocalin 2: An Emerging Player in Iron Homeostasis and Inflammation

Machine learning guided aptamer refinement and discovery

Siderophores in Iron Metabolism: From Mechanism to Therapy Potential

Lipocalin-2 as a therapeutic target for brain injury: An astrocentric perspective

A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis

Lipocalin-2: A Master Mediator of Intestinal and Metabolic Inflammation

NUPR1 is a critical repressor of ferroptosis

Gene interfered-ferroptosis therapy for cancers

Astrocyte‐derived lipocalin‐2 mediates hippocampal damage and cognitive deficits in experimental models of vascular dementia

The novel STING antagonist H151 ameliorates cisplatin-induced acute kidney injury and mitochondrial dysfunction

Astrocytic phagocytosis contributes to demyelination after focal cortical ischemia in mice

C/EBPδ Mediates Immunity to Renal Autoinflammatory Disorders in a Stage-specific Manner

Functions and regulation of lipocalin-2 in gut-origin sepsis: a narrative review

TNFα-induced NLRP3 inflammasome mediates adipocyte dysfunction and activates macrophages through adipocyte-derived lipocalin 2

Increased neutrophil gelatinase-associated lipocalin (NGAL) promotes airway remodelling in chronic obstructive pulmonary disease

Emerging insights into Lipocalin-2: Unraveling its role in Parkinson's Disease

Neutralization of Lipocalin-2 Diminishes Stroke-Reperfusion Injury

Reduced secretion of LCN2 (lipocalin 2) from reactive astrocytes through autophagic and proteasomal regulation alleviates inflammatory stress and neuronal damage

Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment

Lipocalin‐2 (NGAL) Attenuates Autophagy to Exacerbate Cardiac Apoptosis Induced by Myocardial Ischemia

Lipocalin-2 deficiency or blockade protects against aortic abdominal aneurysm development in mice

Lipocalin-2 inhibition alleviates neural injury by microglia ferroptosis suppression after experimental intracerebral hemorrhage in mice via enhancing ferritin light chain expression

NGAL as a Potential Target in Tumor Microenvironment

Neutrophil Gelatinase-Associated Lipocalin From Macrophages Plays a Critical Role in Renal Fibrosis Via the CCL5 (Chemokine Ligand 5)-Th2 Cells-IL4 (Interleukin 4) Pathway

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