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What fraction of cellular DNA turnover becomes cfDNA?

eLife, 2024-02, Vol.12

2024

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Vascular instruction of pancreas development

Development (Cambridge), 2012-08, Vol.139 (16), p.2833-2843

2012

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Metabolic Stress and Compromised Identity of Pancreatic Beta Cells

Frontiers in genetics, 2017-02, Vol.8, p.21-21

2017

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Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease

Nature communications, 2018-11, Vol.9 (1), p.5068-12, Article 5068

2018

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Non-invasive detection of human cardiomyocyte death using methylation patterns of circulating DNA

Nature communications, 2018-04, Vol.9 (1), p.1443-9, Article 1443

2018

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Detecting cell-of-origin and cancer-specific methylation features of cell-free DNA from Nanopore sequencing

Genome Biology, 2022-07, Vol.23 (1), p.1-158, Article 158

2022

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Towards systematic nomenclature for cell-free DNA

Human genetics, 2021-04, Vol.140 (4), p.565-578

2021

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ChIP-seq of plasma cell-free nucleosomes identifies gene expression programs of the cells of origin

Nature biotechnology, 2021-05, Vol.39 (5), p.586-598

2021

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Insulin receptor alternative splicing is regulated by insulin signaling and modulates beta cell survival

Scientific reports, 2016-08, Vol.6 (1), p.31222-31222, Article 31222

2016

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Inhibition of mTORC1 by ER stress impairs neonatal β-cell expansion and predisposes to diabetes in the Akita mouse

eLife, 2018-11, Vol.7

2018

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Elevated brain-derived cell-free DNA among patients with first psychotic episode - a proof-of-concept study

eLife, 2022-06, Vol.11

2022

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Hyperglycaemia induces metabolic dysfunction and glycogen accumulation in pancreatic β-cells

Nature communications, 2016-11, Vol.7 (1), p.13496-15, Article 13496

2016

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Diabetes Risk Gene and Wnt Effector Tcf7l2/TCF4 Controls Hepatic Response to Perinatal and Adult Metabolic Demand

Cell, 2012-12, Vol.151 (7), p.1595-1607

2012

Volltextzugriff (PDF)

Megakaryocyte- and erythroblast-specific cell-free DNA patterns in plasma and platelets reflect thrombopoiesis and erythropoiesis levels

Nature communications, 2023-11, Vol.14 (1), p.7542-7542, Article 7542

2023

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Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis

Genes & development, 2005-09, Vol.19 (18), p.2199-2211

2005

Volltextzugriff (PDF)

Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice

Nature biotechnology, 2014-01, Vol.32 (1), p.76-83

2014

Volltextzugriff (PDF)

Short report: Plasma based biomarkers detect radiation induced brain injury in cancer patients treated for brain metastasis: A pilot study

PloS one, 2023-11, Vol.18 (11), p.e0285646-e0285646

2023

Volltextzugriff (PDF)

Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability

Nature communications, 2017-11, Vol.8 (1), p.1323-10, Article 1323

2017

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Principles of DNA methylation and their implications for biology and medicine

The Lancet (British edition), 2018-09, Vol.392 (10149), p.777-786

2018

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The correlation between high-sensitivity troponin-T and cell-free cardiac DNA in the blood of patients undergoing noncardiac, predominantly vascular surgery

Journal of international medical research, 2024-02, Vol.52 (2), p.3000605241229638-3000605241229638

2024

Volltextzugriff (PDF)

Engineered vascular beds provide key signals to pancreatic hormone-producing cells

PloS one, 2012-07, Vol.7 (7), p.e40741-e40741

2012

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De novo formation of insulin-producing "neo-β cell islets" from intestinal crypts

Cell reports (Cambridge), 2014-03, Vol.6 (6), p.1046-1058

2014

Volltextzugriff (PDF)

Extensive elimination of acinar cells during normal postnatal pancreas growth

Cell reports (Cambridge), 2023-12, Vol.42 (12), p.113457-113457, Article 113457

2023

Volltextzugriff (PDF)

In Vivo Lineage Tracing Defines the Role of Acinar-to-Ductal Transdifferentiation in Inflammatory Ductal Metaplasia

Gastroenterology (New York, N.Y. 1943), 2007-12, Vol.133 (6), p.1999-2009

2007

Volltextzugriff (PDF)

Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function

Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (24), p.9715-9720

2009

Volltextzugriff (PDF)

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What fraction of cellular DNA turnover becomes cfDNA?

Vascular instruction of pancreas development

Metabolic Stress and Compromised Identity of Pancreatic Beta Cells

Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease

Non-invasive detection of human cardiomyocyte death using methylation patterns of circulating DNA

Detecting cell-of-origin and cancer-specific methylation features of cell-free DNA from Nanopore sequencing

Towards systematic nomenclature for cell-free DNA

ChIP-seq of plasma cell-free nucleosomes identifies gene expression programs of the cells of origin

Insulin receptor alternative splicing is regulated by insulin signaling and modulates beta cell survival

Inhibition of mTORC1 by ER stress impairs neonatal β-cell expansion and predisposes to diabetes in the Akita mouse

Elevated brain-derived cell-free DNA among patients with first psychotic episode - a proof-of-concept study

Hyperglycaemia induces metabolic dysfunction and glycogen accumulation in pancreatic β-cells

Diabetes Risk Gene and Wnt Effector Tcf7l2/TCF4 Controls Hepatic Response to Perinatal and Adult Metabolic Demand

Megakaryocyte- and erythroblast-specific cell-free DNA patterns in plasma and platelets reflect thrombopoiesis and erythropoiesis levels

Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis

Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice

Short report: Plasma based biomarkers detect radiation induced brain injury in cancer patients treated for brain metastasis: A pilot study

Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability

Principles of DNA methylation and their implications for biology and medicine

The correlation between high-sensitivity troponin-T and cell-free cardiac DNA in the blood of patients undergoing noncardiac, predominantly vascular surgery

Engineered vascular beds provide key signals to pancreatic hormone-producing cells

De novo formation of insulin-producing "neo-β cell islets" from intestinal crypts

Extensive elimination of acinar cells during normal postnatal pancreas growth

In Vivo Lineage Tracing Defines the Role of Acinar-to-Ductal Transdifferentiation in Inflammatory Ductal Metaplasia

Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function

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