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Benzoxazolone-5-Urea Derivatives as Human Soluble Epoxide Hydrolase (sEH) Inhibitors

ACS omega, 2023-01, Vol.8 (2), p.2445-2454

2023

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Quinazoline-4(3H)‑one-7-carboxamide Derivatives as Human Soluble Epoxide Hydrolase Inhibitors with Developable 5‑Lipoxygenase Activating Protein Inhibition

ACS omega, 2022-10, Vol.7 (41), p.36354-36365

2022

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Vicinal Diaryl-Substituted Isoxazole and Pyrazole Derivatives with In Vitro Growth Inhibitory and In Vivo Antitumor Activity

ACS omega, 2022-10, Vol.7 (41), p.36206-36226

2022

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STIGMA, DISSATISFACTION, DISENGAGEMENT AND INTENTION TO QUIT: A MODEL PROPOSAL

Yaşam becerileri psikoloji dergisi, 2020-06, Vol.4 (7), p.101-114

2020

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Drug discovery approaches targeting 5-lipoxygenase-activating protein (FLAP) for inhibition of cellular leukotriene biosynthesis

European journal of medicinal chemistry, 2018-06, Vol.153, p.34-48

2018

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Synthesis and biological evaluation of novel isoxazole-piperazine hybrids as potential anti-cancer agents with inhibitory effect on liver cancer stem cells

European journal of medicinal chemistry, 2021-10, Vol.221, p.113489-113489, Article 113489

2021

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Synthesis and cellular bioactivities of novel isoxazole derivatives incorporating an arylpiperazine moiety as anticancer agents

Journal of enzyme inhibition and medicinal chemistry, 2018-01, Vol.33 (1), p.1352-1361

2018

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Investigation of the Relationship Between Acute Phase Reactants and Causative Microorganisms in Blood Stream Infections

Ankara Ueniversitesi Tip Fakültesi mecmuasi, 2022-06, Vol.75 (2), p.193-198

2022

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Novel potent benzimidazole-based microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors derived from BRP-201 that also inhibit leukotriene C4 synthase

European journal of medicinal chemistry, 2022-03, Vol.231, p.114167-114167, Article 114167

2022

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Evaluation of Cytotoxic Activity of New Benzimidazole-Piperazine Hybrids Against Human MCF-7 and A549 Cancer Cells

Pharmaceutical chemistry journal, 2020-02, Vol.53 (11), p.1036-1046

2020

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Discovery and Optimization of Piperazine Urea Derivatives as Soluble Epoxide Hydrolase (sEH) Inhibitors

ChemMedChem, 2022-06, Vol.17 (12), p.e202200137-n/a

2022

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Synthesis and preliminary mechanistic evaluation of 5-(p-tolyl)-1-(quinolin-2-yl)pyrazole-3-carboxylic acid amides with potent antiproliferative activity on human cancer cell lines

European journal of medicinal chemistry, 2014-11, Vol.87, p.140-149

2014

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A Multi‐step Virtual Screening Protocol for the Identification of Novel Non‐acidic Microsomal Prostaglandin E2 Synthase‐1 (mPGES‐1) Inhibitors

ChemMedChem, 2019-01, Vol.14 (2), p.273-281

2019

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4,5-Diarylisoxazol-3-carboxylic acids: A new class of leukotriene biosynthesis inhibitors potentially targeting 5-lipoxygenase-activating protein (FLAP)

European journal of medicinal chemistry, 2016-05, Vol.113, p.1-10

2016

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Development and molecular modeling studies of new thiadiazole piperazine urea derivatives as potential fatty acid amide hydrolase inhibitors

Archiv der Pharmazie (Weinheim), 2022-08, Vol.355 (8), p.e2200082-n/a

2022

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Identification of multi-target inhibitors of leukotriene and prostaglandin E2 biosynthesis by structural tuning of the FLAP inhibitor BRP-7

European journal of medicinal chemistry, 2018-04, Vol.150, p.876-899

2018

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Antimigratory effect of pyrazole derivatives through the induction of STAT1 phosphorylation in A549 cancer cells

Journal of pharmacy and pharmacology, 2021-06, Vol.73 (6), p.808-815

2021

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Coronavirus Disease 2019-Related Fulminant Idiopathic Intracranial Hypertension

Journal of pediatric neurology, 2024-08, Vol.22 (4), p.247-254

2024

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Novel 1,3,4-oxadiazole derivatives as highly potent microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors

Bioorganic chemistry, 2024-06, Vol.147, p.107383-107383, Article 107383

2024

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Benzimidazole derivatives as potent and isoform selective tumor-associated carbonic anhydrase IX/XII inhibitors

Bioorganic chemistry, 2020-01, Vol.95, p.103544-103544, Article 103544

2020

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Overview of recent drug discovery approaches for new generation leukotriene A4 hydrolase inhibitors

Expert opinion on drug discovery, 2013-01, Vol.8 (1), p.49-63

2013

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Chromatographic separation and biological evaluation of benzimidazole derivative enantiomers as inhibitors of leukotriene biosynthesis

Journal of pharmaceutical and biomedical analysis, 2014-02, Vol.89, p.88-92

2014

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BRP-187: A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase/5-lipoxygenase-activating protein (FLAP) complex assembly

Biochemical pharmacology, 2016-11, Vol.119, p.17-26

2016

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Pyrazol-3-propanoic acid derivatives as novel inhibitors of leukotriene biosynthesis in human neutrophils

European journal of medicinal chemistry, 2011-10, Vol.46 (10), p.5021-5033

2011

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HLA Genotypes in Turkish Hematopoietic Cell Recipients and Likelihood of Finding a Matched Donor Through Family Searches

Experimental and clinical transplantation, 2019-12, Vol.17 (6), p.813-818

2019

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Benzoxazolone-5-Urea Derivatives as Human Soluble Epoxide Hydrolase (sEH) Inhibitors

Quinazoline-4(3H)‑one-7-carboxamide Derivatives as Human Soluble Epoxide Hydrolase Inhibitors with Developable 5‑Lipoxygenase Activating Protein Inhibition

Vicinal Diaryl-Substituted Isoxazole and Pyrazole Derivatives with In Vitro Growth Inhibitory and In Vivo Antitumor Activity

STIGMA, DISSATISFACTION, DISENGAGEMENT AND INTENTION TO QUIT: A MODEL PROPOSAL

Drug discovery approaches targeting 5-lipoxygenase-activating protein (FLAP) for inhibition of cellular leukotriene biosynthesis

Synthesis and biological evaluation of novel isoxazole-piperazine hybrids as potential anti-cancer agents with inhibitory effect on liver cancer stem cells

Synthesis and cellular bioactivities of novel isoxazole derivatives incorporating an arylpiperazine moiety as anticancer agents

Investigation of the Relationship Between Acute Phase Reactants and Causative Microorganisms in Blood Stream Infections

Novel potent benzimidazole-based microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors derived from BRP-201 that also inhibit leukotriene C4 synthase

Evaluation of Cytotoxic Activity of New Benzimidazole-Piperazine Hybrids Against Human MCF-7 and A549 Cancer Cells

Discovery and Optimization of Piperazine Urea Derivatives as Soluble Epoxide Hydrolase (sEH) Inhibitors

Synthesis and preliminary mechanistic evaluation of 5-(p-tolyl)-1-(quinolin-2-yl)pyrazole-3-carboxylic acid amides with potent antiproliferative activity on human cancer cell lines

A Multi‐step Virtual Screening Protocol for the Identification of Novel Non‐acidic Microsomal Prostaglandin E2 Synthase‐1 (mPGES‐1) Inhibitors

4,5-Diarylisoxazol-3-carboxylic acids: A new class of leukotriene biosynthesis inhibitors potentially targeting 5-lipoxygenase-activating protein (FLAP)

Development and molecular modeling studies of new thiadiazole piperazine urea derivatives as potential fatty acid amide hydrolase inhibitors

Identification of multi-target inhibitors of leukotriene and prostaglandin E2 biosynthesis by structural tuning of the FLAP inhibitor BRP-7

Antimigratory effect of pyrazole derivatives through the induction of STAT1 phosphorylation in A549 cancer cells

Coronavirus Disease 2019-Related Fulminant Idiopathic Intracranial Hypertension

Novel 1,3,4-oxadiazole derivatives as highly potent microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors

Benzimidazole derivatives as potent and isoform selective tumor-associated carbonic anhydrase IX/XII inhibitors

Overview of recent drug discovery approaches for new generation leukotriene A4 hydrolase inhibitors

Chromatographic separation and biological evaluation of benzimidazole derivative enantiomers as inhibitors of leukotriene biosynthesis

BRP-187: A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase/5-lipoxygenase-activating protein (FLAP) complex assembly

Pyrazol-3-propanoic acid derivatives as novel inhibitors of leukotriene biosynthesis in human neutrophils

HLA Genotypes in Turkish Hematopoietic Cell Recipients and Likelihood of Finding a Matched Donor Through Family Searches

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