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Prospects for Antibacterial Discovery and Development

Journal of the American Chemical Society, 2021-12, Vol.143 (50), p.21127-21142

2021

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In situ assembly of enzyme inhibitors using extended tethering

Nature biotechnology, 2003-03, Vol.21 (3), p.308-314

2003

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Applications of Combinatorial Technologies to Drug Discovery. 2. Combinatorial Organic Synthesis, Library Screening Strategies, and Future Directions

Journal of medicinal chemistry, 1994-05, Vol.37 (10), p.1385-1401

1994

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Applications of Combinatorial Technologies to Drug Discovery. 1. Background and Peptide Combinatorial Libraries

Journal of medicinal chemistry, 1994-04, Vol.37 (9), p.1233-1251

1994

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Approaches to Combinatorial Synthesis of Heterocycles: A Solid-Phase Synthesis of 1,4-Dihydropyridines

Journal of organic chemistry, 1996-02, Vol.61 (3), p.924-928

1996

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Combinatorial Organic Synthesis of Highly Functionalized Pyrrolidines: Identification of a Potent Angiotensin Converting Enzyme Inhibitor from a Mercaptoacyl Proline Library

Journal of the American Chemical Society, 1995-07, Vol.117 (26), p.7029-7030

1995

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Combinatorial modification of natural products: Synthesis and in vitro analysis of derivatives of thiazole peptide antibiotic GE2270 A: A-ring modifications

Bioorganic & medicinal chemistry letters, 2003-10, Vol.13 (20), p.3409-3414

2003

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Site-Directed Ligand Discovery

Proceedings of the National Academy of Sciences - PNAS, 2000-08, Vol.97 (17), p.9367-9372

2000

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Farnesyl Diphosphate-Based Inhibitors of Ras Farnesyl Protein Transferase

Journal of medicinal chemistry, 1995-07, Vol.38 (15), p.2906-2921

1995

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The first potent inhibitor of squalene synthase: a profound contribution of an ether oxygen to inhibitor-enzyme interaction

Journal of the American Chemical Society, 1991-10, Vol.113 (22), p.8522-8524

1991

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The identification of cyclooxygenase-1 inhibitors from 4-thiazolidinone combinatorial libraries

Bioorganic & medicinal chemistry letters, 1996-03, Vol.6 (6), p.707-712

1996

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Innovative approaches to novel antibacterial drug discovery

Current opinion in biotechnology, 1997-12, Vol.8 (6), p.757-762

1997

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Phosphorus-containing inhibitors of HMG-CoA reductase. 2. Synthesis and biological activities of a series of substituted pyridines containing a hydroxyphosphinyl moiety

Journal of medicinal chemistry, 1991-09, Vol.34 (9), p.2804-2815

1991

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Phosphorus-containing inhibitors of HMG-CoA reductase. I. 4-[(2-Arylethyl)hydroxyphosphinyl]-3-hydroxybutanoic acids: a new class of cell selective inhibitors of cholesterol biosynthesis

Journal of medicinal chemistry, 1990-11, Vol.33 (11), p.2952-2956

1990

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Applications of small-molecule combinatorial chemistry to drug discovery

Drug discovery today, 1996-04, Vol.1 (4), p.134-144

1996

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Isolation and structure elucidation of oxoxylopine, a new oxoaporphine alkaloid from Stephania abyssinica

Journal of organic chemistry, 1970-05, Vol.35 (5), p.1682-1684

1970

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Combinatorial chemistry of natural products: Solid phase synthesis of D- and L-cycloserine derivatives

Tetrahedron, 1998, Vol.54 (52), p.15879-15890

1998

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Electrocatalytic and Photocatalytic Hydrogen Production from Acidic and Neutral-pH Aqueous Solutions Using Iron Phosphide Nanoparticles

ACS nano, 2014-11, Vol.8 (11), p.11101-11107

2014

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Control of Metal Nanocrystal Size Reveals Metal-Support Interface Role for Ceria Catalysts

Science (American Association for the Advancement of Science), 2013-08, Vol.341 (6147), p.771-773

2013

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Improvements to PATRIC, the all-bacterial Bioinformatics Database and Analysis Resource Center

Nucleic acids research, 2017-01, Vol.45 (D1), p.D535

2017

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Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia

Cell, 2013-02, Vol.152 (4), p.714-726

2013

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Complex Glycan Catabolism by the Human Gut Microbiota: The Bacteroidetes Sus-like Paradigm

The Journal of biological chemistry, 2009-09, Vol.284 (37), p.24673-24677

2009

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Adiponectin receptor 1 conserves docosahexaenoic acid and promotes photoreceptor cell survival

Nature communications, 2015-03, Vol.6 (1), p.6228-6228, Article 6228

2015

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Hippocampal-Prefrontal Theta Transmission Regulates Avoidance Behavior

Neuron (Cambridge, Mass.), 2019-11, Vol.104 (3), p.601-610.e4

2019

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Prospects for Antibacterial Discovery and Development

In situ assembly of enzyme inhibitors using extended tethering

Applications of Combinatorial Technologies to Drug Discovery. 2. Combinatorial Organic Synthesis, Library Screening Strategies, and Future Directions

Applications of Combinatorial Technologies to Drug Discovery. 1. Background and Peptide Combinatorial Libraries

Approaches to Combinatorial Synthesis of Heterocycles: A Solid-Phase Synthesis of 1,4-Dihydropyridines

Combinatorial Organic Synthesis of Highly Functionalized Pyrrolidines: Identification of a Potent Angiotensin Converting Enzyme Inhibitor from a Mercaptoacyl Proline Library

Combinatorial modification of natural products: Synthesis and in vitro analysis of derivatives of thiazole peptide antibiotic GE2270 A: A-ring modifications

Site-Directed Ligand Discovery

Farnesyl Diphosphate-Based Inhibitors of Ras Farnesyl Protein Transferase

The first potent inhibitor of squalene synthase: a profound contribution of an ether oxygen to inhibitor-enzyme interaction

The identification of cyclooxygenase-1 inhibitors from 4-thiazolidinone combinatorial libraries

Innovative approaches to novel antibacterial drug discovery

Phosphorus-containing inhibitors of HMG-CoA reductase. 2. Synthesis and biological activities of a series of substituted pyridines containing a hydroxyphosphinyl moiety

Phosphorus-containing inhibitors of HMG-CoA reductase. I. 4-[(2-Arylethyl)hydroxyphosphinyl]-3-hydroxybutanoic acids: a new class of cell selective inhibitors of cholesterol biosynthesis

Applications of small-molecule combinatorial chemistry to drug discovery

Isolation and structure elucidation of oxoxylopine, a new oxoaporphine alkaloid from Stephania abyssinica

Combinatorial chemistry of natural products: Solid phase synthesis of D- and L-cycloserine derivatives

Electrocatalytic and Photocatalytic Hydrogen Production from Acidic and Neutral-pH Aqueous Solutions Using Iron Phosphide Nanoparticles

Control of Metal Nanocrystal Size Reveals Metal-Support Interface Role for Ceria Catalysts

Improvements to PATRIC, the all-bacterial Bioinformatics Database and Analysis Resource Center

Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia

Complex Glycan Catabolism by the Human Gut Microbiota: The Bacteroidetes Sus-like Paradigm

The PATRIC Bioinformatics Resource Center: expanding data and analysis capabilities

Adiponectin receptor 1 conserves docosahexaenoic acid and promotes photoreceptor cell survival

Hippocampal-Prefrontal Theta Transmission Regulates Avoidance Behavior

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