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Quinazolines with intra-molecular hydrogen bonding scaffold (iMHBS) as PI3K/mTOR dual inhibitors

Bioorganic & medicinal chemistry letters, 2011-02, Vol.21 (4), p.1270-1274

2011

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SARS-CoV-2 papain-like protease (PLpro) inhibitory and antiviral activity of small molecule derivatives for drug leads

Bioorganic & medicinal chemistry letters, 2023-11, Vol.96, p.129489-129489, Article 129489

2023

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Novel M 4 positive allosteric modulators derived from questioning the role and impact of a presumed intramolecular hydrogen-bonding motif in β-amino carboxamide-harboring ligands

Bioorganic & medicinal chemistry letters, 2019-02, Vol.29 (3), p.362

2019

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Targeting epigenetic modulators using PROTAC degraders: Current status and future perspective

Bioorganic & medicinal chemistry letters, 2022-05, Vol.63, p.128653-128653, Article 128653

2022

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Discovery of benzo[g]indoles as a novel class of non-covalent Keap1-Nrf2 protein-protein interaction inhibitor

Bioorganic & medicinal chemistry letters, 2017-11, Vol.27 (22), p.5006-5009

2017

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Cytotoxic cardenolides from the latex of Calotropis procera

Bioorganic & medicinal chemistry letters, 2015-10, Vol.25 (20), p.4615-4620

2015

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Epidithiodiketopiperazine as a pharmacophore for protein lysine methyltransferase G9a inhibitors: Reducing cytotoxicity by structural simplification

Bioorganic & medicinal chemistry letters, 2013-02, Vol.23 (3), p.733-736

2013

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SAH derived potent and selective EZH2 inhibitors

Bioorganic & medicinal chemistry letters, 2015-04, Vol.25 (7), p.1532-1537

2015

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Novel acridinedione derivatives: Design, synthesis, SIRT1 enzyme and tumor cell growth inhibition studies

Bioorganic & medicinal chemistry letters, 2012-05, Vol.22 (9), p.3256-3260

2012

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Identification of 4-hydroxyquinolines inhibitors of p300/CBP histone acetyltransferases

Bioorganic & medicinal chemistry letters, 2009-02, Vol.19 (4), p.1132-1135

2009

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Synthesis and biological evaluation of hydrazidomycin analogues

Bioorganic & medicinal chemistry letters, 2013-11, Vol.23 (22), p.6043-6045

2013

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Identification of a cell-active non-peptide sirtuin inhibitor containing N-thioacetyl lysine

Bioorganic & medicinal chemistry letters, 2009-10, Vol.19 (19), p.5670-5672

2009

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Inhibition of human monoamine oxidase A and B by 5-phenoxy 8-aminoquinoline analogs

Bioorganic & medicinal chemistry letters, 2012-02, Vol.22 (4), p.1701-1704

2012

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Profiling base excision repair glycosylases with synthesized transition state analogs

Bioorganic & medicinal chemistry letters, 2011-09, Vol.21 (17), p.4969-4972

2011

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Unnatural enantiomer of chaetocin shows strong apoptosis-inducing activity through caspase-8/caspase-3 activation

Bioorganic & medicinal chemistry letters, 2010-09, Vol.20 (17), p.5085-5088

2010

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Identification of a potent and stable antiproliferative agent by the prodrug formation of a thiolate histone deacetylase inhibitor

Bioorganic & medicinal chemistry letters, 2007-03, Vol.17 (6), p.1558-1561

2007

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Quinazolines with intra-molecular hydrogen bonding scaffold (iMHBS) as PI3K/mTOR dual inhibitors

SARS-CoV-2 papain-like protease (PLpro) inhibitory and antiviral activity of small molecule derivatives for drug leads

Novel M 4 positive allosteric modulators derived from questioning the role and impact of a presumed intramolecular hydrogen-bonding motif in β-amino carboxamide-harboring ligands

Targeting epigenetic modulators using PROTAC degraders: Current status and future perspective

Discovery of benzo[g]indoles as a novel class of non-covalent Keap1-Nrf2 protein-protein interaction inhibitor

Cytotoxic cardenolides from the latex of Calotropis procera

Epidithiodiketopiperazine as a pharmacophore for protein lysine methyltransferase G9a inhibitors: Reducing cytotoxicity by structural simplification

SAH derived potent and selective EZH2 inhibitors

Novel acridinedione derivatives: Design, synthesis, SIRT1 enzyme and tumor cell growth inhibition studies

Identification of 4-hydroxyquinolines inhibitors of p300/CBP histone acetyltransferases

Synthesis and biological evaluation of hydrazidomycin analogues

Identification of a cell-active non-peptide sirtuin inhibitor containing N-thioacetyl lysine

Inhibition of human monoamine oxidase A and B by 5-phenoxy 8-aminoquinoline analogs

Profiling base excision repair glycosylases with synthesized transition state analogs

Unnatural enantiomer of chaetocin shows strong apoptosis-inducing activity through caspase-8/caspase-3 activation

Identification of a potent and stable antiproliferative agent by the prodrug formation of a thiolate histone deacetylase inhibitor

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