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Extracellular Vesicles as Drug Delivery Systems in Cancer

Pharmaceutics, 2020-11, Vol.12 (12), p.1146

2020

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RhoA downregulation in the murine intestinal epithelium results in chronic Wnt activation and increased tumorigenesis

iScience, 2024-04, Vol.27 (4), p.109400-109400, Article 109400

2024

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Perspectives of nano-carrier drug delivery systems to overcome cancer drug resistance in the clinics

Cancer Drug Resistance, 2021-01

2021

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Mechanisms of inactivation of the receptor tyrosine kinase EPHB2 in colorectal tumors

Cancer research (Chicago, Ill.), 2005-11, Vol.65 (22), p.10170-10173

2005

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Strategies for the production of difficult-to-express full-length eukaryotic proteins using microbial cell factories: production of human alpha-galactosidase A

Applied microbiology and biotechnology, 2015-07, Vol.99 (14), p.5863-5874

2015

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A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition

Nature genetics, 2006-05, Vol.38 (5), p.566-569

2006

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CD300 Heterocomplexes, a New and Family-restricted Mechanism for Myeloid Cell Signaling Regulation

The Journal of biological chemistry, 2010-12, Vol.285 (53), p.41781-41794

2010

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Brush border Myosin Ia has tumor suppressor activity in the intestine

Proceedings of the National Academy of Sciences - PNAS, 2012-01, Vol.109 (5), p.1530-1535

2012

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Na⁺/Monocarboxylate Transport (SMCT) Protein Expression Correlates with Survival in Colon Cancer: Molecular Characterization of SMCT

Proceedings of the National Academy of Sciences - PNAS, 2006-05, Vol.103 (19), p.7270-7275

2006

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EPHB4 and survival of colorectal cancer patients

Cancer research (Chicago, Ill.), 2006-09, Vol.66 (18), p.8943-8948

2006

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Overexpression of the Immunoreceptor CD300f Has a Neuroprotective Role in a Model of Acute Brain Injury

Brain pathology (Zurich, Switzerland), 2012-05, Vol.22 (3), p.318-328

2012

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Somatic mutations in the DNA damage-response genes ATR and CHK1 in sporadic stomach tumors with microsatellite instability

Cancer research (Chicago, Ill.), 2001-11, Vol.61 (21), p.7727-7730

2001

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BRAF mutations characterize colon but not gastric cancer with mismatch repair deficiency

Oncogene, 2003-12, Vol.22 (57), p.9192-9196

2003

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Polymeric micelles targeted against CD44v6 receptor increase niclosamide efficacy against colorectal cancer stem cells and reduce circulating tumor cells in vivo

Journal of controlled release, 2021-03, Vol.331, p.198-212

2021

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Unmet needs in developing nanoparticles for precision medicine

Nanomedicine (London, England), 2017-02, Vol.12 (4), p.271-274

Schwartz, Simo

2017

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Modular protein engineering in emerging cancer therapies

Current pharmaceutical design, 2009-03, Vol.15 (8), p.893-916

2009

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Concomitant RASSF1A hypermethylation and KRAS/BRAF mutations occur preferentially in MSI sporadic colorectal cancer

Oncogene, 2005-11, Vol.24 (51), p.7630-7634

2005

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Germline hypermethylation of the APC promoter is not a frequent cause of familial adenomatous polyposis in APC/MUTYH mutation negative families

International journal of cancer, 2008-03, Vol.122 (6), p.1422-1425

2008

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Unconventional microbial systems for the cost-efficient production of high-quality protein therapeutics

Biotechnology advances, 2013-03, Vol.31 (2), p.140-153

2013

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RSR-2, the Caenorhabditis elegans Ortholog of Human Spliceosomal Component SRm300/SRRM2, Regulates Development by Influencing the Transcriptional Machinery: e1003543

PLoS genetics, 2013-06, Vol.9 (6)

2013

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Extracellular vesicles secreted by triple‐negative breast cancer stem cells trigger premetastatic niche remodeling and metastatic growth in the lungs

International journal of cancer, 2023-05, Vol.152 (10), p.2153-2165

2023

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Impact of Chemical Composition on the Nanostructure and Biological Activity of α‑Galactosidase‑Loaded Nanovesicles for Fabry Disease Treatment

ACS applied materials & interfaces, 2021-02, Vol.13 (7), p.7825-7838

2021

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Intracellular targeting of CD44+ cells with self-assembling, protein only nanoparticles

International journal of pharmaceutics, 2014-10, Vol.473 (1-2), p.286-295

2014

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PAR-5 is a PARty hub in the germline: Multitask proteins in development and disease

Worm (Austin, TX), 2013-01, Vol.2 (1), p.e21834-e21834

2013

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Extracellular Vesicles as Drug Delivery Systems in Cancer

RhoA downregulation in the murine intestinal epithelium results in chronic Wnt activation and increased tumorigenesis

Perspectives of nano-carrier drug delivery systems to overcome cancer drug resistance in the clinics

Mechanisms of inactivation of the receptor tyrosine kinase EPHB2 in colorectal tumors

Strategies for the production of difficult-to-express full-length eukaryotic proteins using microbial cell factories: production of human alpha-galactosidase A

A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition

CD300 Heterocomplexes, a New and Family-restricted Mechanism for Myeloid Cell Signaling Regulation

Brush border Myosin Ia has tumor suppressor activity in the intestine

Na⁺/Monocarboxylate Transport (SMCT) Protein Expression Correlates with Survival in Colon Cancer: Molecular Characterization of SMCT

EPHB4 and survival of colorectal cancer patients

Overexpression of the Immunoreceptor CD300f Has a Neuroprotective Role in a Model of Acute Brain Injury

Somatic mutations in the DNA damage-response genes ATR and CHK1 in sporadic stomach tumors with microsatellite instability

BRAF mutations characterize colon but not gastric cancer with mismatch repair deficiency

Polymeric micelles targeted against CD44v6 receptor increase niclosamide efficacy against colorectal cancer stem cells and reduce circulating tumor cells in vivo

Unmet needs in developing nanoparticles for precision medicine

Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status

Modular protein engineering in emerging cancer therapies

Concomitant RASSF1A hypermethylation and KRAS/BRAF mutations occur preferentially in MSI sporadic colorectal cancer

Germline hypermethylation of the APC promoter is not a frequent cause of familial adenomatous polyposis in APC/MUTYH mutation negative families

Unconventional microbial systems for the cost-efficient production of high-quality protein therapeutics

RSR-2, the Caenorhabditis elegans Ortholog of Human Spliceosomal Component SRm300/SRRM2, Regulates Development by Influencing the Transcriptional Machinery: e1003543

Extracellular vesicles secreted by triple‐negative breast cancer stem cells trigger premetastatic niche remodeling and metastatic growth in the lungs

Impact of Chemical Composition on the Nanostructure and Biological Activity of α‑Galactosidase‑Loaded Nanovesicles for Fabry Disease Treatment

Intracellular targeting of CD44+ cells with self-assembling, protein only nanoparticles

PAR-5 is a PARty hub in the germline: Multitask proteins in development and disease

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