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Valproic acid targets HDAC1/2 and HDAC1/PTEN/Akt signalling to inhibit cell proliferation via the induction of autophagy in gastric cancer

The FEBS journal, 2020-05, Vol.287 (10), p.2118-2133

2020

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Valproic acid reverses sorafenib resistance through inhibiting activated Notch/Akt signaling pathway in hepatocellular carcinoma

Fundamental & clinical pharmacology, 2021-08, Vol.35 (4), p.690-699

2021

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Persistent treatment resistance in genetic generalized epilepsy: A long‐term outcome study in a tertiary epilepsy center

Epilepsia (Copenhagen), 2020-11, Vol.61 (11), p.2452-2460

2020

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Response to the letter to the Editor from Araujo and colleagues on the research article entitled, “Effect of smoking habits and concomitant valproic acid use on relapse in patients with treatment‐resistant schizophrenia receiving clozapine: A 1‐year retrospective cohort study”

Acta psychiatrica Scandinavica, 2024-05, Vol.149 (5), p.436-438

2024

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Association of BDNF risk variant and dorsolateral cortical thickness with long‐term treatment response to valproate in type I bipolar disorder: An exploratory study

American journal of medical genetics. Part B, Neuropsychiatric genetics, 2024-04, Vol.195 (3), p.e32966-n/a

2024

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GABAergic synaptic transmission and cortical oscillation patterns in the primary somatosensory area of a valproic acid rat model of autism spectrum disorder

The European journal of neuroscience, 2023-02, Vol.57 (3), p.527-546

2023

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Antiepileptic drugs: Impacts on human serum paraoxonase‐1

Journal of biochemical and molecular toxicology, 2017-06, Vol.31 (6), p.n/a

2017

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Antiseizure drug efficacy and tolerability in established and novel drug discovery seizure models in outbred vs inbred mice

Epilepsia (Copenhagen), 2020-09, Vol.61 (9), p.2022-2034

2020

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Valproic acid affects neuronal fate and microglial function via enhancing autophagic flux in mice after traumatic brain injury

Journal of neurochemistry, 2020-08, Vol.154 (3), p.284-300

2020

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Valproic acid increased the efficacy of EGFR TKIs on EGFR/TP53 co‐mutated lung cancers and downregulated mutant‐p53 levels

Molecular carcinogenesis, 2024-02, Vol.63 (2), p.275-285

2024

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Valproic acid reduces muscle susceptibility to contraction‐induced functional loss but increases weakness in two murine models of Duchenne muscular dystrophy

Clinical and experimental pharmacology & physiology, 2023-09, Vol.50 (9), p.749-756

2023

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Histone deacetylase inhibition mitigates fibrosis-driven disease progression in recessive dystrophic epidermolysis bullosa

British journal of dermatology (1951), 2024-09, Vol.191 (4), p.568

2024

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The effects of postnatal erythropoietin and nano‐erythropoietin on behavioral alterations by mediating K‐Cl co‐transporter 2 in the valproic acid‐induced rat model of autism

Developmental psychobiology, 2023-01, Vol.65 (1), p.e22353-n/a

2023

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Valproic acid ameliorates cauda equina injury by suppressing HDAC2‐mediated ferroptosis

CNS neuroscience & therapeutics, 2024-04, Vol.30 (4), p.e14524-n/a

2024

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Valproate treatment induces age‐ and sex‐dependent neuronal activity changes according to a patch clamp study

Developmental neurobiology (Hoboken, N.J.), 2024-01, Vol.84 (1), p.32-43

2024

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Sustained release of sulforaphane by bioactive extracellular vesicles for neuroprotective effect on chick model

Journal of biomedical materials research. Part B, Applied biomaterials, 2022-12, Vol.110 (12), p.2636-2648

2022

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Comparative efficacy of valnoctamide and sec‐butylpropylacetamide (SPD) in terminating nerve agent–induced seizures in pediatric rats

Epilepsia (Copenhagen), 2019-02, Vol.60 (2), p.315-321

2019

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Xanthotoxin enhances the anticonvulsant potency of levetiracetam and valproate in the 6‐Hz corneal stimulation model in mice

Fundamental & clinical pharmacology, 2022-02, Vol.36 (1), p.133-142

2022

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SMA valiant trial: A prospective, double-blind, placebo-controlled trial of valproic acid in ambulatory adults with spinal muscular atrophy

Muscle & nerve, 2014-02, Vol.49 (2), p.187-192

2014

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Differential inflammation responses determine the variable phenotypes of epilepsy induced by GABRG2 mutations

CNS neuroscience & therapeutics, 2024-02, Vol.30 (2), p.e14583-n/a

2024

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Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

The EMBO journal, 2001-12, Vol.20 (24), p.6969-6978

2001

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Valproic Acid and Lithium Meditate Anti‐Inflammatory Effects by Differentially Modulating Dendritic Cell Differentiation and Function

Journal of cellular physiology, 2017-05, Vol.232 (5), p.1176-1186

2017

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The effects of valproic acid on early pregnancy human placentas: Pilot ex vivo analysis in cultured placental villi

Epilepsia (Copenhagen), 2019-05, Vol.60 (5), p.e47-e51

2019

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The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2

The EMBO journal, 2003-07, Vol.22 (13), p.3411-3420

2003

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The potential protective effect of liraglutide on valproic acid induced liver injury in rats: Targeting HMGB1/RAGE axis and RIPK3/MLKL mediated necroptosis

Cell biochemistry and function, 2023-12, Vol.41 (8), p.1209-1219

2023

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Valproic acid targets HDAC1/2 and HDAC1/PTEN/Akt signalling to inhibit cell proliferation via the induction of autophagy in gastric cancer

Valproic acid reverses sorafenib resistance through inhibiting activated Notch/Akt signaling pathway in hepatocellular carcinoma

Persistent treatment resistance in genetic generalized epilepsy: A long‐term outcome study in a tertiary epilepsy center

Response to the letter to the Editor from Araujo and colleagues on the research article entitled, “Effect of smoking habits and concomitant valproic acid use on relapse in patients with treatment‐resistant schizophrenia receiving clozapine: A 1‐year retrospective cohort study”

Association of BDNF risk variant and dorsolateral cortical thickness with long‐term treatment response to valproate in type I bipolar disorder: An exploratory study

GABAergic synaptic transmission and cortical oscillation patterns in the primary somatosensory area of a valproic acid rat model of autism spectrum disorder

Antiepileptic drugs: Impacts on human serum paraoxonase‐1

Antiseizure drug efficacy and tolerability in established and novel drug discovery seizure models in outbred vs inbred mice

Valproic acid affects neuronal fate and microglial function via enhancing autophagic flux in mice after traumatic brain injury

Valproic acid increased the efficacy of EGFR TKIs on EGFR/TP53 co‐mutated lung cancers and downregulated mutant‐p53 levels

Valproic acid reduces muscle susceptibility to contraction‐induced functional loss but increases weakness in two murine models of Duchenne muscular dystrophy

Histone deacetylase inhibition mitigates fibrosis-driven disease progression in recessive dystrophic epidermolysis bullosa

The effects of postnatal erythropoietin and nano‐erythropoietin on behavioral alterations by mediating K‐Cl co‐transporter 2 in the valproic acid‐induced rat model of autism

Valproic acid ameliorates cauda equina injury by suppressing HDAC2‐mediated ferroptosis

Valproate treatment induces age‐ and sex‐dependent neuronal activity changes according to a patch clamp study

Sustained release of sulforaphane by bioactive extracellular vesicles for neuroprotective effect on chick model

Comparative efficacy of valnoctamide and sec‐butylpropylacetamide (SPD) in terminating nerve agent–induced seizures in pediatric rats

Xanthotoxin enhances the anticonvulsant potency of levetiracetam and valproate in the 6‐Hz corneal stimulation model in mice

SMA valiant trial: A prospective, double-blind, placebo-controlled trial of valproic acid in ambulatory adults with spinal muscular atrophy

Differential inflammation responses determine the variable phenotypes of epilepsy induced by GABRG2 mutations

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

Valproic Acid and Lithium Meditate Anti‐Inflammatory Effects by Differentially Modulating Dendritic Cell Differentiation and Function

The effects of valproic acid on early pregnancy human placentas: Pilot ex vivo analysis in cultured placental villi

The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2

The potential protective effect of liraglutide on valproic acid induced liver injury in rats: Targeting HMGB1/RAGE axis and RIPK3/MLKL mediated necroptosis

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