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A fluorogenic probe for predicting treatment response in non-small cell lung cancer with EGFR-activating mutations

Nature communications, 2022-11, Vol.13 (1), p.6944-19, Article 6944

2022

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SARS-CoV-2 SUD2 and Nsp5 Conspire to Boost Apoptosis of Respiratory Epithelial Cells via an Augmented Interaction with the G-Quadruplex of BclII

mBio, 2023-04, Vol.14 (2), p.e0335922-e0335922

2023

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Influence of calcination temperature on the performance of Pd-Mn/SiO2-Al2O3 catalysts for ozone decomposition

Journal of hazardous materials, 2009-12, Vol.172 (2-3), p.631-634

2009

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Allosteric inhibition of HIF-2α as a novel therapy for clear cell renal cell carcinoma

Drug discovery today, 2019-12, Vol.24 (12), p.2332-2340

2019

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Simultaneous Monitoring of HOCl and Viscosity with Drug-Induced Pyroptosis in Live Cells and Acute Lung Injury

Analytical chemistry (Washington), 2022-09, Vol.94 (35), p.12144-12151

2022

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Insight into the binding mode of HIF-2 agonists through molecular dynamic simulations and biological validation

European journal of medicinal chemistry, 2021-02, Vol.211, p.112999, Article 112999

2021

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Seasonal bacterial community succession in four typical wastewater treatment plants: correlations between core microbes and process performance

Scientific reports, 2018-03, Vol.8 (1), p.4566-11, Article 4566

2018

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Design, Synthesis, and Biological Evaluation of Heterocyclic-Fused Pyrimidine Chemotypes Guided by X‑ray Crystal Structure with Potential Antitumor and Anti-multidrug Resistance Efficacy Targeting the Colchicine Binding Site

Journal of medicinal chemistry, 2023-03, Vol.66 (5), p.3588-3620

2023

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Dual-FRET aptasensor for rapid screening of Ochratoxin A in food samples

Sensors and actuators. B, Chemical, 2024-06, Vol.408, p.135515, Article 135515

2024

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Perspectives and challenges in developing small molecules targeting purine nucleoside phosphorylase

European journal of medicinal chemistry, 2024-05, Vol.271, p.116437-116437, Article 116437

2024

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RIPK2 inhibitors for disease therapy: Current status and perspectives

European journal of medicinal chemistry, 2023-11, Vol.259, p.115683-115683, Article 115683

2023

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Novel Medicinal Chemistry Strategies Targeting CDK5 for Drug Discovery

Journal of medicinal chemistry, 2023-06, Vol.66 (11), p.7140-7161

2023

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The synthesis and bioactivity of pyrrolo[2,3-d]pyrimidine derivatives as tyrosine kinase inhibitors for NSCLC cells with EGFR mutations

European journal of medicinal chemistry, 2021-11, Vol.224, p.113711-113711, Article 113711

2021

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Therapeutic potential of targeting polo-like kinase 4

European journal of medicinal chemistry, 2024-02, Vol.265, p.116115-116115, Article 116115

2024

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Design, synthesis and biological evaluation of naphthyl amide derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors

Bioorganic & medicinal chemistry, 2024-09, Vol.111, p.117844, Article 117844

2024

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Discovery of carbamate-based salicylic acid derivatives as novel cholinesterase inhibitor

Journal of molecular structure, 2023-03, Vol.1276, p.134804, Article 134804

2023

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Discovery of dual inhibitors of topoisomerase I and Cyclooxygenase-2 for colon cancer therapy

European journal of medicinal chemistry, 2022-10, Vol.240, p.114560-114560, Article 114560

2022

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Discovery of a Potent and Orally Bioavailable Hypoxia-Inducible Factor 2α (HIF-2α) Agonist and Its Synergistic Therapy with Prolyl Hydroxylase Inhibitors for the Treatment of Renal Anemia

Journal of medicinal chemistry, 2021-12, Vol.64 (23), p.17384-17402

2021

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A near-infrared fluorescent probe for visualizing viscosity fluxes in live cells and idiopathic pulmonary fibrosis

Sensors and actuators. B, Chemical, 2022-11, Vol.371, p.132575, Article 132575

2022

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Application of cation-π interactions in enzyme-substrate binding: Design, synthesis, biological evaluation, and molecular dynamics insights of novel hydrophilic substrates for NQO1

European journal of medicinal chemistry, 2021-10, Vol.221, p.113515-113515, Article 113515

2021

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A small-molecule probe for monitoring binding to prolyl hydroxylase domain 2 by fluorescence polarisation

Chemical communications (Cambridge, England), 2020-11, Vol.56 (91), p.14199-1422

2020

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Discovery of prolyl hydroxylase 2 inhibitors with new chemical scaffolds as in vivo active erythropoietin inducers through a combined virtual screening strategy

Chemical biology & drug design, 2020-02, Vol.95 (2), p.270-278

2020

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Pt/La-Ba-Al2O3/H-ZSM-5 Catalyst for Treating Hydrogen-Powered Vehicle Exhaust

Chinese journal of catalysis, 2009-05, Vol.30 (5), p.381-383

2009

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Lyotropic and Thermotropic Phase Transitions in Films of Ionene−Alkyl Sulfate Complexes

Langmuir, 2005-07, Vol.21 (15), p.6797-6804

2005

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Catalytic Decomposition of Ozone in Ground Air by Manganese-Based Monolith Catalysts

Chinese journal of catalysis, 2009, Vol.30 (1), p.1-3

2009

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A fluorogenic probe for predicting treatment response in non-small cell lung cancer with EGFR-activating mutations

SARS-CoV-2 SUD2 and Nsp5 Conspire to Boost Apoptosis of Respiratory Epithelial Cells via an Augmented Interaction with the G-Quadruplex of BclII

Influence of calcination temperature on the performance of Pd-Mn/SiO2-Al2O3 catalysts for ozone decomposition

Allosteric inhibition of HIF-2α as a novel therapy for clear cell renal cell carcinoma

Simultaneous Monitoring of HOCl and Viscosity with Drug-Induced Pyroptosis in Live Cells and Acute Lung Injury

Insight into the binding mode of HIF-2 agonists through molecular dynamic simulations and biological validation

Seasonal bacterial community succession in four typical wastewater treatment plants: correlations between core microbes and process performance

Design, Synthesis, and Biological Evaluation of Heterocyclic-Fused Pyrimidine Chemotypes Guided by X‑ray Crystal Structure with Potential Antitumor and Anti-multidrug Resistance Efficacy Targeting the Colchicine Binding Site

Dual-FRET aptasensor for rapid screening of Ochratoxin A in food samples

Perspectives and challenges in developing small molecules targeting purine nucleoside phosphorylase

RIPK2 inhibitors for disease therapy: Current status and perspectives

Novel Medicinal Chemistry Strategies Targeting CDK5 for Drug Discovery

The synthesis and bioactivity of pyrrolo[2,3-d]pyrimidine derivatives as tyrosine kinase inhibitors for NSCLC cells with EGFR mutations

Therapeutic potential of targeting polo-like kinase 4

Design, synthesis and biological evaluation of naphthyl amide derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors

Discovery of carbamate-based salicylic acid derivatives as novel cholinesterase inhibitor

Discovery of dual inhibitors of topoisomerase I and Cyclooxygenase-2 for colon cancer therapy

Discovery of a Potent and Orally Bioavailable Hypoxia-Inducible Factor 2α (HIF-2α) Agonist and Its Synergistic Therapy with Prolyl Hydroxylase Inhibitors for the Treatment of Renal Anemia

A near-infrared fluorescent probe for visualizing viscosity fluxes in live cells and idiopathic pulmonary fibrosis

Application of cation-π interactions in enzyme-substrate binding: Design, synthesis, biological evaluation, and molecular dynamics insights of novel hydrophilic substrates for NQO1

A small-molecule probe for monitoring binding to prolyl hydroxylase domain 2 by fluorescence polarisation

Discovery of prolyl hydroxylase 2 inhibitors with new chemical scaffolds as in vivo active erythropoietin inducers through a combined virtual screening strategy

Pt/La-Ba-Al2O3/H-ZSM-5 Catalyst for Treating Hydrogen-Powered Vehicle Exhaust

Lyotropic and Thermotropic Phase Transitions in Films of Ionene−Alkyl Sulfate Complexes

Catalytic Decomposition of Ozone in Ground Air by Manganese-Based Monolith Catalysts

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