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PD-1 Blockade in Rhesus Macaques: Impact on Chronic Infection and Prophylactic Vaccination

The Journal of immunology (1950), 2009-01, Vol.182 (2), p.980-987

2009

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Integrase Inhibitors and Cellular Immunity Suppress Retroviral Replication in Rhesus Macaques

Science (American Association for the Advancement of Science), 2004-07, Vol.305 (5683), p.528-532

2004

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Design and Synthesis of 8-Hydroxy-[1,6]Naphthyridines as Novel Inhibitors of HIV-1 Integrase in Vitro and in Infected Cells

Journal of medicinal chemistry, 2003-02, Vol.46 (4), p.453-456

2003

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A Naphthyridine Carboxamide Provides Evidence for Discordant Resistance between Mechanistically Identical Inhibitors of HIV-1 Integrase

Proceedings of the National Academy of Sciences - PNAS, 2004-08, Vol.101 (31), p.11233-11238

2004

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Fourier Transform Mass Spectrometry and Nuclear Magnetic Resonance Analysis for the Rapid and Accurate Characterization of Hexacosanoylceramide

International journal of molecular sciences, 2016-07, Vol.17 (7), p.1024-1024

2016

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L-735,524: The Design of a Potent and Orally Bioavailable HIV Protease Inhibitor

Journal of medicinal chemistry, 1994-10, Vol.37 (21), p.3443-3451

1994

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4-Aryl-2,4-dioxobutanoic Acid Inhibitors of HIV-1 Integrase and Viral Replication in Cells

Journal of medicinal chemistry, 2000-12, Vol.43 (26), p.4923-4926

2000

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A series of 5-aminosubstituted 4-fluorobenzyl-8-hydroxy-[1,6]naphthyridine-7-carboxamide HIV-1 integrase inhibitors

Bioorganic & medicinal chemistry letters, 2006-06, Vol.16 (11), p.2900-2904

2006

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A novel coaxial electrospray ionization method for characterizing hexacosanoylceramides by Fourier transform ion cyclotron resonance mass spectrometry

Rapid communications in mass spectrometry, 2005-01, Vol.19 (10), p.1257-1262

2005

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Development of Orally Active Oxytocin Antagonists: Studies on 1-(1-{4-[1-(2-Methyl-1-oxidopyridin-3-ylmethyl)piperidin-4-yloxy]-2- methoxybenzoyl}piperidin-4-yl)-1,4-dihydrobenz[d][1,3]oxazin-2-one (L-372,662) and Related Pyridines

Journal of medicinal chemistry, 1998-06, Vol.41 (12), p.2146-2163

1998

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Benzocycloalkyl amines as novel C-termini for HIV protease inhibitors

Journal of medicinal chemistry, 1991-03, Vol.34 (3), p.1228-1230

1991

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On the Chemistry of the 18-Deoxycytochalasin H, HIV-1 Protease Inhibitor, L-696,474. 1: Degradation Studies Leading to the 2-Isoindolone Core

Heterocycles, 1995-03, Vol.41 (3), p.403

1995

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A Priori Prediction of Activity for HIV-1 Protease Inhibitors Employing Energy Minimization in the Active Site

Journal of medicinal chemistry, 1996-05, Vol.39 (11), p.2280-2280

1996

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On the Chemistry of the 18-Deoxycytochalasin H, HIV-1 Protease Inhibitor, L-696,474. 2: Novel Ring Annulations

Heterocycles, 1995-03, Vol.41 (3), p.409

1995

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Applications of microwave-assisted organic synthesis on the multigram scale

Current opinion in drug discovery & development, 2005-11, Vol.8 (6), p.701

2005

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Structure-affinity relationships of arylquinolizines at .alpha.-adrenoceptors

Journal of medicinal chemistry, 1988-03, Vol.31 (3), p.641-645

1988

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Design and synthesis of HIV protease inhibitors. Variations of the carboxyterminus of the HIV protease inhibitor L-682,679

Journal of medicinal chemistry, 1991-09, Vol.34 (9), p.2852-2857

1991

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Regioselective functionalization. .beta. Substituent effects on the regioselectivity of Baeyer-Villiger oxidations of 3-substituted 2-azabicyclo[2.2.2]octan-5-ones (isoquinuclidin-5-ones)

Journal of organic chemistry, 1982-12, Vol.47 (27), p.5239-5243

1982

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Adrenoceptor and tetrabenazine antagonism activities of some pyridinyltetrahydropyridines

Journal of medicinal chemistry, 1984-09, Vol.27 (9), p.1182-1185

1984

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N-(1,3,4,6,7,12b-hexahydro-2H-benzo[b]furo[2,3-a]quinolizin-2-yl)-N-methyl-2-hydroxyethanesulfonamide: a potent and selective .alpha.2-adrenoceptor antagonist

Journal of medicinal chemistry, 1985-12, Vol.28 (12), p.1756-1759

1985

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Design and synthesis of N-alkylated saccharins as selective α-1a adrenergic receptor antagonists

Bioorganic & medicinal chemistry letters, 1998-09, Vol.8 (18), p.2467-2472

1998

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A convergent synthesis of novel conformationally restricted HIV-1 protease inhibitors

Tetrahedron letters, 1994-07, Vol.35 (29), p.5153-5156

1994

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Design and synthesis of HIV protease inhibitors. Variations of the carboxy terminus of the HIV protease inhibitor L-682,679

Journal of medicinal chemistry, 1991-09, Vol.34 (9), p.2852-2857

1991

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Thiophene derivatives as extremely high affinity P3′ ligands for the hydroxyethylpiperazine class of HIV-1 protease inhibitors

Bioorganic & medicinal chemistry letters, 1995-01, Vol.5 (2), p.185-190

1995

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Thiophene derivatives as extremely high affinity P 3′ ligands for the hydroxyethylpiperazine class of HIV-1 protease inhibitors

Bioorganic & medicinal chemistry letters, 1995-01, Vol.5 (2), p.185-190

1995

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PD-1 Blockade in Rhesus Macaques: Impact on Chronic Infection and Prophylactic Vaccination

Integrase Inhibitors and Cellular Immunity Suppress Retroviral Replication in Rhesus Macaques

Design and Synthesis of 8-Hydroxy-[1,6]Naphthyridines as Novel Inhibitors of HIV-1 Integrase in Vitro and in Infected Cells

A Naphthyridine Carboxamide Provides Evidence for Discordant Resistance between Mechanistically Identical Inhibitors of HIV-1 Integrase

Fourier Transform Mass Spectrometry and Nuclear Magnetic Resonance Analysis for the Rapid and Accurate Characterization of Hexacosanoylceramide

L-735,524: The Design of a Potent and Orally Bioavailable HIV Protease Inhibitor

4-Aryl-2,4-dioxobutanoic Acid Inhibitors of HIV-1 Integrase and Viral Replication in Cells

A series of 5-aminosubstituted 4-fluorobenzyl-8-hydroxy-[1,6]naphthyridine-7-carboxamide HIV-1 integrase inhibitors

A novel coaxial electrospray ionization method for characterizing hexacosanoylceramides by Fourier transform ion cyclotron resonance mass spectrometry

Development of Orally Active Oxytocin Antagonists: Studies on 1-(1-{4-[1-(2-Methyl-1-oxidopyridin-3-ylmethyl)piperidin-4-yloxy]-2- methoxybenzoyl}piperidin-4-yl)-1,4-dihydrobenz[d][1,3]oxazin-2-one (L-372,662) and Related Pyridines

Benzocycloalkyl amines as novel C-termini for HIV protease inhibitors

On the Chemistry of the 18-Deoxycytochalasin H, HIV-1 Protease Inhibitor, L-696,474. 1: Degradation Studies Leading to the 2-Isoindolone Core

A Priori Prediction of Activity for HIV-1 Protease Inhibitors Employing Energy Minimization in the Active Site

On the Chemistry of the 18-Deoxycytochalasin H, HIV-1 Protease Inhibitor, L-696,474. 2: Novel Ring Annulations

Applications of microwave-assisted organic synthesis on the multigram scale

Structure-affinity relationships of arylquinolizines at .alpha.-adrenoceptors

Design and synthesis of HIV protease inhibitors. Variations of the carboxyterminus of the HIV protease inhibitor L-682,679

Regioselective functionalization. .beta. Substituent effects on the regioselectivity of Baeyer-Villiger oxidations of 3-substituted 2-azabicyclo[2.2.2]octan-5-ones (isoquinuclidin-5-ones)

Adrenoceptor and tetrabenazine antagonism activities of some pyridinyltetrahydropyridines

N-(1,3,4,6,7,12b-hexahydro-2H-benzo[b]furo[2,3-a]quinolizin-2-yl)-N-methyl-2-hydroxyethanesulfonamide: a potent and selective .alpha.2-adrenoceptor antagonist

Design and synthesis of N-alkylated saccharins as selective α-1a adrenergic receptor antagonists

A convergent synthesis of novel conformationally restricted HIV-1 protease inhibitors

Design and synthesis of HIV protease inhibitors. Variations of the carboxy terminus of the HIV protease inhibitor L-682,679

Thiophene derivatives as extremely high affinity P3′ ligands for the hydroxyethylpiperazine class of HIV-1 protease inhibitors

Thiophene derivatives as extremely high affinity P 3′ ligands for the hydroxyethylpiperazine class of HIV-1 protease inhibitors

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