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Hemoglobin: Structure, Function and Allostery

Sub-cellular biochemistry, 2020, Vol.94, p.345-382

2020

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New developments in anti‐sickling agents: can drugs directly prevent the polymerization of sickle haemoglobin in vivo?

British journal of haematology, 2016-10, Vol.175 (1), p.24-30

2016

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Psiadia punctulata major flavonoids alleviate exaggerated vasoconstriction produced by advanced glycation end products

PloS one, 2019-09, Vol.14 (9), p.e0222101-e0222101

2019

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Docking and Molecular Dynamic Investigations of Phenylspirodrimanes as Cannabinoid Receptor-2 Agonists

Molecules (Basel, Switzerland), 2022-12, Vol.28 (1), p.44

2022

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Therapeutic Strategies to Alter the Oxygen Affinity of Sickle Hemoglobin

Hematology/oncology clinics of North America, 2014-04, Vol.28 (2), p.217-231

2014

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Inborn errors in the vitamin B6 salvage enzymes associated with neonatal epileptic encephalopathy and other pathologies

Biochimie, 2021-04, Vol.183, p.18-29

2021

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Elucidating the Interaction between Pyridoxine 5'-Phosphate Oxidase and Dopa Decarboxylase: Activation of B6-Dependent Enzyme

International journal of molecular sciences, 2022-12, Vol.24 (1), p.642

2022

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The antisickling agent, 5‐hydroxymethyl‐2‐furfural: Other potential pharmacological applications

Medicinal research reviews, 2024-11, Vol.44 (6), p.2707-2729

2024

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A Triazole Disulfide Compound Increases the Affinity of Hemoglobin for Oxygen and Reduces the Sickling of Human Sickle Cells

Molecular pharmaceutics, 2018-05, Vol.15 (5), p.1954-1963

2018

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Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Aromatic Aldehydes as Drug Candidates for the Treatment of Sickle Cell Disease

Molecules (Basel, Switzerland), 2022-10, Vol.27 (20), p.6835

2022

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Modulating hemoglobin allostery for treatment of sickle cell disease: current progress and intellectual property

Expert opinion on therapeutic patents, 2022-02, Vol.32 (2), p.115-130

2022

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Correction: Zebrafish larvae exposed to ginkgotoxin exhibit seizure-like behavior that is relieved by pyridoxal-5′-phosphate, GABA and anti-epileptic drugs

Disease models & mechanisms, 2023-10, Vol.16 (10)

2023

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Incorporating valsartan in sesame oil enriched self-nanoemulsifying system-loaded liquisolid tablets to improve its bioavailability

International journal of pharmaceutics, 2023-05, Vol.639, p.122966-122966, Article 122966

2023

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Quantitative assessment of the in-vitro binding kinetics of antisickling aromatic aldehydes with hemoglobin A: A universal HPLC-UV/Vis method to quantitate Schiff-base adduct formation

Journal of pharmaceutical and biomedical analysis, 2023-01, Vol.223, p.115152-115152, Article 115152

2023

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3D Interaction Homology: Hydropathic Analyses of the “π–Cation” and “π–π” Interaction Motifs in Phenylalanine, Tyrosine, and Tryptophan Residues

Journal of chemical information and modeling, 2021-06, Vol.61 (6), p.2937-2956

2021

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Hemoglobin–ligand binding: Understanding Hb function and allostery on atomic level

Biochimica et biophysica acta, 2011-06, Vol.1814 (6), p.797-809

2011

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Characterization of the Staphylococcus aureus rRNA Methyltransferase Encoded by orfX, the Gene Containing the Staphylococcal Chromosome Cassette mec (SCCmec) Insertion Site

The Journal of biological chemistry, 2013-01, Vol.288 (1), p.132-140

2013

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Not Only Antimicrobial: Metronidazole Mitigates the Virulence of Proteus mirabilis Isolated from Macerated Diabetic Foot Ulcer

Applied sciences, 2021-08, Vol.11 (15), p.6847

2021

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Development of 3D-Printed, Liquisolid and Directly Compressed Glimepiride Tablets, Loaded with Black Seed Oil Self-Nanoemulsifying Drug Delivery System: In Vitro and In Vivo Characterization

Pharmaceuticals (Basel, Switzerland), 2022-01, Vol.15 (1), p.68

2022

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Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease

Scientific reports, 2017-11, Vol.7 (1), p.15281-16, Article 15281

2017

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Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect

Journal of enzyme inhibition and medicinal chemistry, 2021-01, Vol.36 (1), p.802-818

2021

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Diminishing the Pathogenesis of the Food-Borne Pathogen Serratia marcescens by Low Doses of Sodium Citrate

Biology (Basel, Switzerland), 2023-03, Vol.12 (4), p.504

2023

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New Antiproliferative Triflavanone from Thymelaea hirsuta -Isolation, Structure Elucidation and Molecular Docking Studies

Molecules (Basel, Switzerland), 2021-01, Vol.26 (3), p.739

2021

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Characterization of the Escherichia coli pyridoxal 5′‐phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability

Protein science, 2022-11, Vol.31 (11), p.e4471-n/a

2022

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Design, Synthesis, and Antisickling Investigation of a Thiazolidine Prodrug of TD-7 That Prolongs the Duration of Action of Antisickling Aromatic Aldehyde

Pharmaceutics, 2023-10, Vol.15 (11), p.2547

2023

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Hemoglobin: Structure, Function and Allostery

New developments in anti‐sickling agents: can drugs directly prevent the polymerization of sickle haemoglobin in vivo?

Psiadia punctulata major flavonoids alleviate exaggerated vasoconstriction produced by advanced glycation end products

Docking and Molecular Dynamic Investigations of Phenylspirodrimanes as Cannabinoid Receptor-2 Agonists

Therapeutic Strategies to Alter the Oxygen Affinity of Sickle Hemoglobin

Inborn errors in the vitamin B6 salvage enzymes associated with neonatal epileptic encephalopathy and other pathologies

Elucidating the Interaction between Pyridoxine 5'-Phosphate Oxidase and Dopa Decarboxylase: Activation of B6-Dependent Enzyme

The antisickling agent, 5‐hydroxymethyl‐2‐furfural: Other potential pharmacological applications

A Triazole Disulfide Compound Increases the Affinity of Hemoglobin for Oxygen and Reduces the Sickling of Human Sickle Cells

Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Aromatic Aldehydes as Drug Candidates for the Treatment of Sickle Cell Disease

Modulating hemoglobin allostery for treatment of sickle cell disease: current progress and intellectual property

Correction: Zebrafish larvae exposed to ginkgotoxin exhibit seizure-like behavior that is relieved by pyridoxal-5′-phosphate, GABA and anti-epileptic drugs

Incorporating valsartan in sesame oil enriched self-nanoemulsifying system-loaded liquisolid tablets to improve its bioavailability

Quantitative assessment of the in-vitro binding kinetics of antisickling aromatic aldehydes with hemoglobin A: A universal HPLC-UV/Vis method to quantitate Schiff-base adduct formation

3D Interaction Homology: Hydropathic Analyses of the “π–Cation” and “π–π” Interaction Motifs in Phenylalanine, Tyrosine, and Tryptophan Residues

Hemoglobin–ligand binding: Understanding Hb function and allostery on atomic level

Characterization of the Staphylococcus aureus rRNA Methyltransferase Encoded by orfX, the Gene Containing the Staphylococcal Chromosome Cassette mec (SCCmec) Insertion Site

Not Only Antimicrobial: Metronidazole Mitigates the Virulence of Proteus mirabilis Isolated from Macerated Diabetic Foot Ulcer

Development of 3D-Printed, Liquisolid and Directly Compressed Glimepiride Tablets, Loaded with Black Seed Oil Self-Nanoemulsifying Drug Delivery System: In Vitro and In Vivo Characterization

Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease

Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect

Diminishing the Pathogenesis of the Food-Borne Pathogen Serratia marcescens by Low Doses of Sodium Citrate

New Antiproliferative Triflavanone from Thymelaea hirsuta -Isolation, Structure Elucidation and Molecular Docking Studies

Characterization of the Escherichia coli pyridoxal 5′‐phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability

Design, Synthesis, and Antisickling Investigation of a Thiazolidine Prodrug of TD-7 That Prolongs the Duration of Action of Antisickling Aromatic Aldehyde

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