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Studying the effect of solubilizing agents on drug diffusion through the unstirred water layer (UWL) by localized spectroscopy

European journal of pharmaceutics and biopharmaceutics, 2019-06, Vol.139, p.205-212

2019

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Parallel artificial membrane permeability assay (PAMPA) - Is it better than Caco-2 for human passive permeability prediction?

Mini reviews in medicinal chemistry, 2010-10, Vol.10 (11), p.1071-1076

2010

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Prediction of Liquid–Liquid Phase Separation at the Dissolving Drug Salt Particle Surface

Molecular pharmaceutics, 2023-06, Vol.20 (6), p.3140-3149

2023

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Estimation of effective intestinal membrane permeability considering bile micelle solubilisation

International journal of pharmaceutics, 2009-02, Vol.368 (1-2), p.116-122

Sugano, Kiyohiko

2009

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Towards a better mechanistic comprehension of drug permeation and absorption: Introducing the diffusion-partitioning interplay

International journal of pharmaceutics, 2021-10, Vol.608, p.121116-121116, Article 121116

2021

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Effect of the unstirred water layer on permeability enhancement by hydrophilic cyclodextrins

International journal of pharmaceutics, 2007-09, Vol.342 (1), p.250-253

2007

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Practical Approach to Modeling the Impact of Amorphous Drug Nanoparticles on the Oral Absorption of Poorly Soluble Drugs

Molecular pharmaceutics, 2020-01, Vol.17 (1), p.180-189

2020

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Effect of Mechanical Agitation on Cationic Liposome Transport across an Unstirred Water Layer in Caco-2 Cells

Biological and Pharmaceutical Bulletin, 2016/08/01, Vol.39(8), pp.1293-1299

2016

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Designing a Novel Coamorphous Salt Formulation of Telmisartan with Amlodipine to Enhance Permeability and Oral Absorption

Molecular pharmaceutics, 2023-08, Vol.20 (8), p.4071-4085

2023

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Possible reduction of effective thickness of intestinal unstirred water layer by particle drifting effect

International journal of pharmaceutics, 2010-03, Vol.387 (1), p.103-109

Sugano, Kiyohiko

2010

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Pharmaceutical applications of cyclodextrins: effects on drug permeation through biological membranes

Journal of pharmacy and pharmacology, 2011-09, Vol.63 (9), p.1119-1135

2011

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Combined effects of the drug distribution and mucus diffusion properties of self-microemulsifying drug delivery systems on the oral absorption of fenofibrate

International journal of pharmaceutics, 2018-07, Vol.546 (1-2), p.263-271

2018

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An Openable Artificial Intestinal Tract System Enables the Evaluation of Drug Absorption in Caco-2 Cells through the Reduction in Thickness of the Unstirred Water Layer

Biological and Pharmaceutical Bulletin, 2019/05/01, Vol.42(5), pp.840-844

2019

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The Solubility–Permeability Interplay: Mechanistic Modeling and Predictive Application of the Impact of Micellar Solubilization on Intestinal Permeation

Molecular pharmaceutics, 2011-10, Vol.8 (5), p.1848-1856

2011

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Prediction of food effect by bile micelles on oral drug absorption considering free fraction in intestinal fluid

European journal of pharmaceutical sciences, 2010-05, Vol.40 (2), p.118-124

2010

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The Solubility–Permeability Interplay When Using Cosolvents for Solubilization: Revising the Way We Use Solubility-Enabling Formulations

Molecular pharmaceutics, 2012-03, Vol.9 (3), p.581-590

2012

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Toward Successful Cyclodextrin Based Solubility-Enabling Formulations for Oral Delivery of Lipophilic Drugs: Solubility–Permeability Trade-Off, Biorelevant Dissolution, and the Unstirred Water Layer

Molecular pharmaceutics, 2017-06, Vol.14 (6), p.2138-2146

2017

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Methacrylate-Copolymer Eudragit EPO as a Solubility-Enabling Excipient for Anionic Drugs: Investigation of Drug Solubility, Intestinal Permeability, and Their Interplay

Molecular pharmaceutics, 2019-07, Vol.16 (7), p.2884-2891

2019

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Importance of the unstirred water layer and hepatocyte membrane integrity in vitro for quantification of intrinsic metabolic clearance

Drug metabolism and disposition, 2018-03, Vol.46 (3), p.268-278

2018

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Prediction of oral drug absorption in humans by theoretical passive absorption model

International journal of pharmaceutics, 2005-04, Vol.293 (1), p.183-192

2005

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Impact of Drug-Rich Colloids of Itraconazole and HPMCAS on Membrane Flux in Vitro and Oral Bioavailability in Rats

Molecular pharmaceutics, 2017-07, Vol.14 (7), p.2437-2449

2017

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An evaluation of the relative roles of the unstirred water layer and receptor sink in limiting the in-vitro intestinal permeability of drug compounds of varying lipophilicity

Journal of pharmacy and pharmacology, 2008-10, Vol.60 (10), p.1311-1319

2008

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PAMPA—a drug absorption in vitro model: 7. Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones

European journal of pharmaceutical sciences, 2004-03, Vol.21 (4), p.429-441

2004

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Theoretical investigation of passive intestinal membrane permeability using Monte Carlo method to generate drug-like molecule population

International journal of pharmaceutics, 2009-05, Vol.373 (1), p.55-61

Sugano, Kiyohiko

2009

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Physicochemical properties of water and its effect on drug delivery A commentary

International journal of pharmaceutics, 2008-04, Vol.354 (1-2), p.248-254

2008

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Studying the effect of solubilizing agents on drug diffusion through the unstirred water layer (UWL) by localized spectroscopy

Parallel artificial membrane permeability assay (PAMPA) - Is it better than Caco-2 for human passive permeability prediction?

Prediction of Liquid–Liquid Phase Separation at the Dissolving Drug Salt Particle Surface

Estimation of effective intestinal membrane permeability considering bile micelle solubilisation

Towards a better mechanistic comprehension of drug permeation and absorption: Introducing the diffusion-partitioning interplay

Effect of the unstirred water layer on permeability enhancement by hydrophilic cyclodextrins

Practical Approach to Modeling the Impact of Amorphous Drug Nanoparticles on the Oral Absorption of Poorly Soluble Drugs

Effect of Mechanical Agitation on Cationic Liposome Transport across an Unstirred Water Layer in Caco-2 Cells

Designing a Novel Coamorphous Salt Formulation of Telmisartan with Amlodipine to Enhance Permeability and Oral Absorption

Possible reduction of effective thickness of intestinal unstirred water layer by particle drifting effect

Pharmaceutical applications of cyclodextrins: effects on drug permeation through biological membranes

Combined effects of the drug distribution and mucus diffusion properties of self-microemulsifying drug delivery systems on the oral absorption of fenofibrate

An Openable Artificial Intestinal Tract System Enables the Evaluation of Drug Absorption in Caco-2 Cells through the Reduction in Thickness of the Unstirred Water Layer

The Solubility–Permeability Interplay: Mechanistic Modeling and Predictive Application of the Impact of Micellar Solubilization on Intestinal Permeation

Prediction of food effect by bile micelles on oral drug absorption considering free fraction in intestinal fluid

The Solubility–Permeability Interplay When Using Cosolvents for Solubilization: Revising the Way We Use Solubility-Enabling Formulations

Toward Successful Cyclodextrin Based Solubility-Enabling Formulations for Oral Delivery of Lipophilic Drugs: Solubility–Permeability Trade-Off, Biorelevant Dissolution, and the Unstirred Water Layer

Methacrylate-Copolymer Eudragit EPO as a Solubility-Enabling Excipient for Anionic Drugs: Investigation of Drug Solubility, Intestinal Permeability, and Their Interplay

Importance of the unstirred water layer and hepatocyte membrane integrity in vitro for quantification of intrinsic metabolic clearance

Prediction of oral drug absorption in humans by theoretical passive absorption model

Impact of Drug-Rich Colloids of Itraconazole and HPMCAS on Membrane Flux in Vitro and Oral Bioavailability in Rats

An evaluation of the relative roles of the unstirred water layer and receptor sink in limiting the in-vitro intestinal permeability of drug compounds of varying lipophilicity

PAMPA—a drug absorption in vitro model: 7. Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones

Theoretical investigation of passive intestinal membrane permeability using Monte Carlo method to generate drug-like molecule population

Physicochemical properties of water and its effect on drug delivery A commentary

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