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Mercapturic Acid Urinary Metabolites of 3-Butene-1,2-diol as in Vivo Evidence for the Formation of Hydroxymethylvinyl Ketone in Mice and Rats

Chemical research in toxicology, 2004-06, Vol.17 (6), p.819-826

2004

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Methimazole protection of rats against chemically induced kidney damage in vivo

The Journal of pharmacology and experimental therapeutics, 1992-01, Vol.260 (1), p.393

1992

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Synthesis and Biochemical Characterization of N1-, N2-, and N7-Guanosine Adducts of Butadiene Monoxide

Chemical research in toxicology, 1996-01, Vol.9 (1), p.126-132

1996

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Cysteine Conjugate b-Lyase Activity of Rat Erythrocytes and Formation of b-Lyase-Derived Globin Monoadducts and Cross-Links after in Vitro Exposure of Erythrocytes to S-(1,2-Dichlorovinyl)-l-cysteine

Chemical research in toxicology, 2009-07, Vol.22 (7), p.1351-1358

2009

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Characterization of the methionine S-oxidase activity of rat liver and kidney microsomes: immunochemical and kinetic evidence for FMO3 being the major catalyst

Archives of biochemistry and biophysics, 1996-09, Vol.333 (1), p.109-116

1996

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Reactive metabolites of 1,3-butadiene: DNA and hemoglobin adduct formation and potential roles in carcinogenicity

Advances in experimental medicine and biology, 2001, Vol.500, p.93

2001

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Pharmacokinetics and short-term clinicopathologic changes after intravenous administration of a high dose of methimazole in dogs

American journal of veterinary research, 1994-11, Vol.55 (11), p.1597-1601

1994

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Oxidative Metabolism of Seleno-L-methionine to L-Methionine Selenoxide by Flavin-Containing Monooxygenases

Chemical research in toxicology, 2006-12, Vol.19 (12), p.1643-1649

2006

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Myeloperoxidase-Mediated Bioactivation of Olefins

Advances in Molecular Toxicology, 2018, Vol.12, p.123-150

2018

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Characterization of 1,2,3,4-Diepoxybutane–2′-Deoxyguanosine Cross-Linking Products Formed at Physiological and Non-Physiological Conditions

Chemical research in toxicology, 2006-04, Vol.19 (4), p.547-555

2006

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Nephrotoxic amino acid and glutathione S-conjugates: formation and renal activation

Advances in experimental medicine and biology, 1986, Vol.197, p.443

1986

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GSH oxidation to GSSG preceded seleno‐L‐methionine cytotoxicity in freshly isolated rat hepatocytes

The FASEB journal, 2007, Vol.21 (6), p.A813-A814

2007

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DISTINCT TISSUE DISTRIBUTION OF METABOLITES OF THE NOVEL GLUTATHIONE-ACTIVATED THIOPURINE PRODRUGS CIS -6-(2-ACETYLVINYLTHIO)PURINE AND TRANS -6-(2-ACETYLVINYLTHIO)GUANINE AND 6-THIOGUANINE IN THE MOUSE

Drug metabolism and disposition, 2003-06, Vol.31 (6), p.718-726

2003

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The Glutathione-activated Thiopurine Prodrugs trans-6-(2-Acetylvinylthio)guanine and cis-6-(2-Acetylvinylthio)purine Cause Less in Vivo Toxicity than 6-Thioguanine after Single- and Multiple-Dose Regimens 1 Supported in part by Grant DK44295 (to A. A. E.) from the National Institute of Diabetes, Digestive, and Kidney Diseases. 1

Molecular cancer therapeutics, 2002-11, Vol.1 (13), p.1211

2002

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Potential role of the flavin-containing monooxygenases in the metabolism of endogenous compounds: Multisubstrate flavin-containing monoxygenases (FMOs)

Chemico-biological interactions, 1995, Vol.96 (1), p.47-55

ELFARRA, A. A

1995

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Characterization of four N-3-thymidine adducts formed in vitro by the reaction of thymidine and butadiene monoxide

Carcinogenesis (New York), 1997-12, Vol.18 (12), p.1993-1998

1997

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Chemical modification of deoxycytidine at different sites yields adducts of different stabilities: characterization of N3- and O2-deoxycytidine and N3-deoxyuridine adducts of butadiene monoxide

Archives of biochemistry and biophysics, 1997-07, Vol.343 (1), p.63

1997

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Characterization of N super(1)- and N super(6)-adenosine adducts and N super(1)-inosine adducts formed by the reaction of butadiene monoxide with adenosine: Evidence for the N super(1)-adenosine adducts as major initial products

Chemical research in toxicology, 1996-01, Vol.9 (5), p.875-881

1996

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Synthesis and biochemical characterization of N super(1)-, N super(2)-, and N super(7)-guanosine adducts of butadiene monoxide

Chemical research in toxicology, 1996-01, Vol.9 (1), p.126-132

1996

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The Responsiveness of Students to Pictorial Depth Cues and the Understanding of Diagrams of Three-dimensional Structures

British educational research journal, 1984-04, Vol.10 (1), p.49-62

1984

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Oxidation of Cysteine S-Conjugates by Rabbit Liver Microsomes and cDNA-Expressed Flavin-Containing Mono-oxygenases: Studies withS-(1,2-Dichlorovinyl)-l-cysteine,S-(1,2,2-Trichlorovinyl)-l-cysteine,S-Allyl-l-cysteine, andS-Benzyl-l-cysteine

Molecular pharmacology, 1997-03, Vol.51 (3), p.507

1997

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Glutathione conjugation of perchloroethylene in rats and mice in vitro: Sex-, and tissue-dependent differences

Toxicology and applied pharmacology, 1998-05, Vol.150 (1), p.49-57

1998

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S-(2-hydroxy-3-buten-1-y)glutathione and S-(1-hydroxy-3-buten-2-yl)glutathione are in vivo metabolites of butadienes monoxide : detection and quantitation in bile

Chemical research in toxicology, 1992, Vol.5 (6), p.787-790

1992

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Reactivity of cysteine S-conjugate sulfoxides : formation of S-[1-chloro-2-(S-glutathionyl)vinyl]-L-cystein sulfoxide with glutathione

Chemical research in toxicology, 1991, Vol.4 (6), p.655-660

1991

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Biosynthesis and biotransformation of glutathioneS-Conjugates to toxic metabolites

CRC critical reviews in toxicology, 1988, Vol.18 (4), p.311-341

1988

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Mercapturic Acid Urinary Metabolites of 3-Butene-1,2-diol as in Vivo Evidence for the Formation of Hydroxymethylvinyl Ketone in Mice and Rats

Methimazole protection of rats against chemically induced kidney damage in vivo

Synthesis and Biochemical Characterization of N1-, N2-, and N7-Guanosine Adducts of Butadiene Monoxide

Cysteine Conjugate b-Lyase Activity of Rat Erythrocytes and Formation of b-Lyase-Derived Globin Monoadducts and Cross-Links after in Vitro Exposure of Erythrocytes to S-(1,2-Dichlorovinyl)-l-cysteine

Characterization of the methionine S-oxidase activity of rat liver and kidney microsomes: immunochemical and kinetic evidence for FMO3 being the major catalyst

Reactive metabolites of 1,3-butadiene: DNA and hemoglobin adduct formation and potential roles in carcinogenicity

Pharmacokinetics and short-term clinicopathologic changes after intravenous administration of a high dose of methimazole in dogs

Oxidative Metabolism of Seleno-L-methionine to L-Methionine Selenoxide by Flavin-Containing Monooxygenases

Myeloperoxidase-Mediated Bioactivation of Olefins

Characterization of 1,2,3,4-Diepoxybutane–2′-Deoxyguanosine Cross-Linking Products Formed at Physiological and Non-Physiological Conditions

Nephrotoxic amino acid and glutathione S-conjugates: formation and renal activation

GSH oxidation to GSSG preceded seleno‐L‐methionine cytotoxicity in freshly isolated rat hepatocytes

DISTINCT TISSUE DISTRIBUTION OF METABOLITES OF THE NOVEL GLUTATHIONE-ACTIVATED THIOPURINE PRODRUGS CIS -6-(2-ACETYLVINYLTHIO)PURINE AND TRANS -6-(2-ACETYLVINYLTHIO)GUANINE AND 6-THIOGUANINE IN THE MOUSE

Potential role of the flavin-containing monooxygenases in the metabolism of endogenous compounds: Multisubstrate flavin-containing monoxygenases (FMOs)

Characterization of four N-3-thymidine adducts formed in vitro by the reaction of thymidine and butadiene monoxide

Chemical modification of deoxycytidine at different sites yields adducts of different stabilities: characterization of N3- and O2-deoxycytidine and N3-deoxyuridine adducts of butadiene monoxide

Characterization of N super(1)- and N super(6)-adenosine adducts and N super(1)-inosine adducts formed by the reaction of butadiene monoxide with adenosine: Evidence for the N super(1)-adenosine adducts as major initial products

Synthesis and biochemical characterization of N super(1)-, N super(2)-, and N super(7)-guanosine adducts of butadiene monoxide

The Responsiveness of Students to Pictorial Depth Cues and the Understanding of Diagrams of Three-dimensional Structures

Oxidation of Cysteine S-Conjugates by Rabbit Liver Microsomes and cDNA-Expressed Flavin-Containing Mono-oxygenases: Studies withS-(1,2-Dichlorovinyl)-l-cysteine,S-(1,2,2-Trichlorovinyl)-l-cysteine,S-Allyl-l-cysteine, andS-Benzyl-l-cysteine

Glutathione conjugation of perchloroethylene in rats and mice in vitro: Sex-, and tissue-dependent differences

S-(2-hydroxy-3-buten-1-y)glutathione and S-(1-hydroxy-3-buten-2-yl)glutathione are in vivo metabolites of butadienes monoxide : detection and quantitation in bile

Reactivity of cysteine S-conjugate sulfoxides : formation of S-[1-chloro-2-(S-glutathionyl)vinyl]-L-cystein sulfoxide with glutathione

Biosynthesis and biotransformation of glutathioneS-Conjugates to toxic metabolites

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