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Repair pathway for PARP-1 DNA-protein crosslinks

DNA repair, 2019-01, Vol.73, p.71-77

2019

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Oxidized nucleotide insertion by pol β confounds ligation during base excision repair

Nature communications, 2017-01, Vol.8 (1), p.14045-11, Article 14045

2017

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Systematic screening for CYP3A4 genetic polymorphisms in a Han Chinese population

Pharmacogenomics, 2017-03, Vol.18 (4), p.369-379

2017

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Transcriptional mutagenesis mediated by 8-oxoG induces translational errors in mammalian cells

Proceedings of the National Academy of Sciences - PNAS, 2018-04, Vol.115 (16), p.4218-4222

2018

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The Pol β variant containing exon α is deficient in DNA polymerase but has full dRP lyase activity

Scientific reports, 2019-07, Vol.9 (1), p.9928-11, Article 9928

2019

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Assessments of CYP-inhibition-based drug-drug interaction between vonoprazan and poziotinib in vitro and in vivo

Pharmaceutical biology, 2023-12, Vol.61 (1), p.356-361

2023

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An identification and functional evaluation of a novel CYP2C9 variant CYP2C962

Chemico-biological interactions, 2020-08, Vol.327, p.109168-109168, Article 109168

2020

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Adipose‐specific deletion of Kif5b exacerbates obesity and insulin resistance in a mouse model of diet‐induced obesity

The FASEB journal, 2017-06, Vol.31 (6), p.2533-2547

2017

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Identification and drug metabolic characterization of four new CYP2C9 variants CYP2C972 - 75 in the Chinese Han population

Frontiers in pharmacology, 2022-12, Vol.13, p.1007268-1007268

2022

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Characterization of 15 CYP2J2 variants identified in the Chinese Han population on the metabolism of ebastine and terfenadine in vitro

Frontiers in pharmacology, 2023-05, Vol.14, p.1186824-1186824

2023

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In Vitro Functional Assessment of 22 Newly Identified CYP2D6 Allelic Variants in the Chinese Population

Basic & clinical pharmacology & toxicology, 2015-07, Vol.117 (1), p.39-43

2015

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Effects of 22 Novel CYP2D6 Variants Found in the Chinese Population on the Bufuralol and Dextromethorphan Metabolisms In Vitro

Basic & clinical pharmacology & toxicology, 2016-03, Vol.118 (3), p.190-199

2016

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Genetic variants, haplotype determination, and function of novel alleles of CYP2B6 in a Han Chinese population

Heliyon, 2024-04, Vol.10 (7), p.e28952-e28952, Article e28952

2024

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Naringenin has an inhibitory effect on rivaroxaban in rats both in vitro and in vivo

Pharmacology research & perspectives, 2021-05, Vol.9 (3)

2021

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Effects of CYP2C19 variants on methadone metabolism in vitro

Drug testing and analysis, 2017-04, Vol.9 (4), p.634-639

2017

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Functional characterization of the defective CYP2C9 variant CYP2C918

Pharmacology research & perspectives, 2021-02, Vol.9 (1), p.e00718-n/a

2021

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In vitro and in vivo characterization of 13 CYP2C9 allelic variants found in Chinese Han population

Drug metabolism and disposition, 2015-04, Vol.43 (4), p.561-569

2015

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Effect of CYP2D6 genetic polymorphism on the metabolism of citalopram in vitro

Drug metabolism and pharmacokinetics, 2016-04, Vol.31 (2), p.133-138

2016

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Functional characterization of 22 novel CYP2D6 variants for the metabolism of Tamoxifen

Journal of pharmacy and pharmacology, 2016-06, Vol.68 (6), p.819-825

2016

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Characterization of a Novel CYP2C9 Mutation (1009C>A) Detected in a Warfarin-Sensitive Patient

Journal of Pharmacological Sciences, 2014/06/20, Vol.125(2), pp.150-156

2014

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MTH1 suppression enhances the stemness of MCF7 through upregulation of STAT3

Free radical biology & medicine, 2022-08, Vol.188, p.447-458

2022

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Oxidative Damage to RNA and Expression Patterns of MTH1 in the Hippocampi of Senescence-Accelerated SAMP8 Mice and Alzheimer’s Disease Patients

Neurochemical research, 2011-08, Vol.36 (8), p.1558-1565

2011

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Role of cytochrome P450 2D6 genetic polymorphism in carvedilol hydroxylation in vitro

Drug design, development and therapy, 2016-01, Vol.10 (Issue 1), p.1909-1916

2016

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In vitro assessment of 24 CYP2D6 allelic isoforms on the metabolism of methadone

Drug testing and analysis, 2017-02, Vol.9 (2), p.216-220

2017

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The role of CYP2C9 genetic polymorphism in carvedilol O-desmethylation in vitro

European journal of drug metabolism and pharmacokinetics, 2016-02, Vol.41 (1), p.79-86

2016

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Repair pathway for PARP-1 DNA-protein crosslinks

Oxidized nucleotide insertion by pol β confounds ligation during base excision repair

Systematic screening for CYP3A4 genetic polymorphisms in a Han Chinese population

Transcriptional mutagenesis mediated by 8-oxoG induces translational errors in mammalian cells

The Pol β variant containing exon α is deficient in DNA polymerase but has full dRP lyase activity

Assessments of CYP-inhibition-based drug-drug interaction between vonoprazan and poziotinib in vitro and in vivo

An identification and functional evaluation of a novel CYP2C9 variant CYP2C962

Adipose‐specific deletion of Kif5b exacerbates obesity and insulin resistance in a mouse model of diet‐induced obesity

Identification and drug metabolic characterization of four new CYP2C9 variants CYP2C972 - 75 in the Chinese Han population

Characterization of 15 CYP2J2 variants identified in the Chinese Han population on the metabolism of ebastine and terfenadine in vitro

In Vitro Functional Assessment of 22 Newly Identified CYP2D6 Allelic Variants in the Chinese Population

Effects of 22 Novel CYP2D6 Variants Found in the Chinese Population on the Bufuralol and Dextromethorphan Metabolisms In Vitro

Genetic variants, haplotype determination, and function of novel alleles of CYP2B6 in a Han Chinese population

Naringenin has an inhibitory effect on rivaroxaban in rats both in vitro and in vivo

Effects of CYP2C19 variants on methadone metabolism in vitro

Functional characterization of the defective CYP2C9 variant CYP2C918

In vitro and in vivo characterization of 13 CYP2C9 allelic variants found in Chinese Han population

Effect of CYP2D6 genetic polymorphism on the metabolism of citalopram in vitro

Functional characterization of 22 novel CYP2D6 variants for the metabolism of Tamoxifen

Characterization of a Novel CYP2C9 Mutation (1009C>A) Detected in a Warfarin-Sensitive Patient

MTH1 suppression enhances the stemness of MCF7 through upregulation of STAT3

Oxidative Damage to RNA and Expression Patterns of MTH1 in the Hippocampi of Senescence-Accelerated SAMP8 Mice and Alzheimer’s Disease Patients

Role of cytochrome P450 2D6 genetic polymorphism in carvedilol hydroxylation in vitro

In vitro assessment of 24 CYP2D6 allelic isoforms on the metabolism of methadone

The role of CYP2C9 genetic polymorphism in carvedilol O-desmethylation in vitro

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