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Discovery of pyrido[2,3-d]pyrimidine-based inhibitors of HCV NS5A

Bioorganic & medicinal chemistry letters, 2013-06, Vol.23 (12), p.3627-3630

2013

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Discovery and optimization of novel constrained pyrrolopyridone BET family inhibitors

Bioorganic & medicinal chemistry letters, 2018-06, Vol.28 (10), p.1804-1810

2018

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Methylpyrrole inhibitors of BET bromodomains

Bioorganic & medicinal chemistry letters, 2017-05, Vol.27 (10), p.2225-2233

2017

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Differentiation of in vitro transcriptional repression and activation profiles of selective glucocorticoid modulators

Bioorganic & medicinal chemistry letters, 2004-04, Vol.14 (7), p.1721-1727

2004

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Des-A-ring benzothiadiazines: Inhibitors of HCV genotype 1 NS5B RNA-dependent RNA polymerase

Bioorganic & medicinal chemistry, 2008-04, Vol.18 (8), p.2735-2738

2008

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Adenosine kinase inhibitors: polar 7-Substitutent of pyridopyrimidine derivatives improving their locomotor selectivity

Bioorganic & medicinal chemistry letters, 2003-09, Vol.13 (18), p.3041-3044

2003

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Synthesis and biological evaluation of novel, selective, nonsteroidal glucocorticoid receptor antagonists

Bioorganic & medicinal chemistry letters, 2004-05, Vol.14 (9), p.2079-2082

2004

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Pyridopyrimidine analogues as novel adenosine kinase inhibitors

Bioorganic & medicinal chemistry letters, 2001-08, Vol.11 (16), p.2071-2074

2001

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A new class of potent non-imidazole H 3 antagonists: 2-aminoethylbenzofurans

Bioorganic & medicinal chemistry letters, 2004-02, Vol.14 (3), p.689-693

2004

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Hemes and Hemoproteins. 5: Kinetics of the Peroxidatic Activity of Microperoxidase-8: Model for the Peroxidase Enzymes

Journal of inorganic biochemistry, 1987-07, Vol.30 (3), p.203-217

1987

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Dipeptide isosteres. 2. Synthesis of hydroxyethylene dipeptide isostere diastereomers from a common γ-lactone intermediate. Preparation of renin and HIV-1 protease inhibitor transition state mimics

Tetrahedron, 1993, Vol.49 (39), p.8739-8756

1993

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D‐Amino Acid Homopiperazine Amides: Discovery of A‐320436, a Potent and Selective Non‐Imidazole Histamine H 3 ‐Receptor Antagonist

Archiv der Pharmazie (Weinheim), 2004-04, Vol.337 (4), p.219-229

2004

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Activation of H2O2 by P450: evidence that the hydroxylating intermediate is iron(III)-coordinated H2O2 and not the ferryl FeO3+ complex

Journal of the Chemical Society. Chemical communications, 1995 (22), p.2297

1995

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Reduction of bis(histidine)hemin; model for the proton-coupled reduction of hemoproteins

Journal of the American Chemical Society, 1981-01, Vol.103 (1), p.186-188

1981

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Hemes and hemoproteins: 1: Preparation and analysis of the heme-containing octapeptide (microperoxidase-8) and identification of the monomeric form in aqueous solution

Journal of inorganic biochemistry, 1986-08, Vol.27 (4), p.227-243

1986

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Mechanism of Co-methylation of Co corrinoids in the presence of thiols

Journal of the Chemical Society. Chemical communications, 1993 (8), p.701-702

1993

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Zero-field pulsed response and dipolar couplings in systems of spin I=1 nuclei

Journal of the Chemical Society, Faraday Transactions 2, 1987, Vol.83 (12), p.2261-2269

1987

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Methyl transfer from nitrogen to cobalt : model for the B12-dependent methyl transfer enzymes

Journal of the Chemical Society. Chemical communications, 1994 (11), p.1333-1334

1994

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Carbon-skeleton rearrangement of the alkyl ligand in a vitamin B12 derivative

Journal of the Chemical Society. Chemical communications, 1976 (23), p.988

1976

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Hemes and hemeproteins: 2:The pH-dependent equilibria of microperoxidase-8 and characterization of the coordination sphere of Fe(III)

Journal of inorganic biochemistry, 1986-08, Vol.27 (4), p.245-254

1986

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Experimental determination of the standard reduction potential of the gold(I) ion

Journal of the Chemical Society. Chemical communications, 1978 (14), p.606

1978

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Evidence for adduct formation in the solubilisation of hydrophobic compounds by aqueous solutions of urea

Journal of the Chemical Society, Faraday Transactions 1: Physical Chemistry in Condensed Phases, 1989, Vol.85 (9), p.2713-2721

1989

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DDT Synergists. The Synthesis and Properties of Some 2,2-Difluoro-1,1-diarylethanols and 2-Fluoro-1,1-diarylethenes

Journal of organic chemistry, 1957-10, Vol.22 (10), p.1210-1213

1957

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A New Method for Hydrolyzing 2-Aryl-4,4-Dimethyl-2-Oxazolines to Aryl Carboxylic Acids

Synthetic communications, 1992-01, Vol.22 (1), p.13-22

1992

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5-Membered ring heterocyclic carboxylic acids as angiotensin II antagonists

Bioorganic & medicinal chemistry letters, 1994-01, Vol.4 (1), p.169-172

1994

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Discovery of pyrido[2,3-d]pyrimidine-based inhibitors of HCV NS5A

Discovery and optimization of novel constrained pyrrolopyridone BET family inhibitors

Methylpyrrole inhibitors of BET bromodomains

Differentiation of in vitro transcriptional repression and activation profiles of selective glucocorticoid modulators

Des-A-ring benzothiadiazines: Inhibitors of HCV genotype 1 NS5B RNA-dependent RNA polymerase

Adenosine kinase inhibitors: polar 7-Substitutent of pyridopyrimidine derivatives improving their locomotor selectivity

Synthesis and biological evaluation of novel, selective, nonsteroidal glucocorticoid receptor antagonists

Pyridopyrimidine analogues as novel adenosine kinase inhibitors

A new class of potent non-imidazole H 3 antagonists: 2-aminoethylbenzofurans

Hemes and Hemoproteins. 5: Kinetics of the Peroxidatic Activity of Microperoxidase-8: Model for the Peroxidase Enzymes

Dipeptide isosteres. 2. Synthesis of hydroxyethylene dipeptide isostere diastereomers from a common γ-lactone intermediate. Preparation of renin and HIV-1 protease inhibitor transition state mimics

D‐Amino Acid Homopiperazine Amides: Discovery of A‐320436, a Potent and Selective Non‐Imidazole Histamine H 3 ‐Receptor Antagonist

Activation of H2O2 by P450: evidence that the hydroxylating intermediate is iron(III)-coordinated H2O2 and not the ferryl FeO3+ complex

Reduction of bis(histidine)hemin; model for the proton-coupled reduction of hemoproteins

Hemes and hemoproteins: 1: Preparation and analysis of the heme-containing octapeptide (microperoxidase-8) and identification of the monomeric form in aqueous solution

Mechanism of Co-methylation of Co corrinoids in the presence of thiols

Zero-field pulsed response and dipolar couplings in systems of spin I=1 nuclei

Methyl transfer from nitrogen to cobalt : model for the B12-dependent methyl transfer enzymes

Carbon-skeleton rearrangement of the alkyl ligand in a vitamin B12 derivative

Hemes and hemeproteins: 2:The pH-dependent equilibria of microperoxidase-8 and characterization of the coordination sphere of Fe(III)

Experimental determination of the standard reduction potential of the gold(I) ion

Evidence for adduct formation in the solubilisation of hydrophobic compounds by aqueous solutions of urea

DDT Synergists. The Synthesis and Properties of Some 2,2-Difluoro-1,1-diarylethanols and 2-Fluoro-1,1-diarylethenes

A New Method for Hydrolyzing 2-Aryl-4,4-Dimethyl-2-Oxazolines to Aryl Carboxylic Acids

5-Membered ring heterocyclic carboxylic acids as angiotensin II antagonists

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