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Intranasal respiratory syncytial virus vaccine attenuated by codon-pair deoptimization of seven open reading frames is genetically stable and elicits mucosal and systemic immunity and protection against challenge virus replication in hamsters

PLoS pathogens, 2024-05, Vol.20 (5), p.e1012198-e1012198

2024

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Efficacy of a virus-vectored vaccine against human and bovine respiratory syncytial virus infections

Science translational medicine, 2015-08, Vol.7 (300), p.300ra127

2015

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Mucosal immunization with a low-energy electron inactivated respiratory syncytial virus vaccine protects mice without Th2 immune bias

Frontiers in immunology, 2024, Vol.15, p.1382318-1382318

2024

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A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism

Nature communications, 2015-09, Vol.6 (1), p.8143-8143, Article 8143

2015

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Chimeric bovine/human parainfluenza virus type 3 expressing respiratory syncytial virus (RSV) F glycoprotein: effect of insert position on expression, replication, immunogenicity, stability, and protection against RSV infection

Journal of virology, 2014-04, Vol.88 (8), p.4237-4250

2014

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Formulation of the respiratory syncytial virus fusion protein with a polymer-based combination adjuvant promotes transient and local innate immune responses and leads to improved adaptive immunity

Vaccine, 2016-09, Vol.34 (42), p.5114-5124

2016

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Immunological Lessons from Respiratory Syncytial Virus Vaccine Development

Immunity (Cambridge, Mass.), 2019-09, Vol.51 (3), p.429-442

2019

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Prefusion F Protein–Based Respiratory Syncytial Virus Immunization in Pregnancy

The New England journal of medicine, 2022-04, Vol.386 (17), p.1615-1626

2022

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RNA-RNA interactions between respiratory syncytial virus and miR-26 and miR-27 are associated with regulation of cell cycle and antiviral immunity

Nucleic acids research, 2024-05, Vol.52 (9), p.4872

2024

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Immunology of bovine respiratory syncytial virus in calves

Molecular immunology, 2015-07, Vol.66 (1), p.48-56

2015

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Recombinant bovine respiratory syncytial virus with deletion of the SH gene induces increased apoptosis and pro-inflammatory cytokines in vitro, and is attenuated and induces protective immunity in calves

Journal of general virology, 2014-06, Vol.95 (Pt 6), p.1244-1254

2014

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Viral N 6 -methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus

Nature communications, 2019-10, Vol.10 (1), p.4595-18

2019

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Chimpanzee adenovirus- and MVA-vectored respiratory syncytial virus vaccine is safe and immunogenic in adults

Science translational medicine, 2015-08, Vol.7 (300), p.300ra126

2015

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Novel antigens for RSV vaccines

Current opinion in immunology, 2015-08, Vol.35, p.30-38

2015

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Live-Attenuated Respiratory Syncytial Virus Vaccine With M2-2 Deletion and With Small Hydrophobic Noncoding Region Is Highly Immunogenic in Children

The Journal of infectious diseases, 2020-06, Vol.221 (12), p.2050-2059

2020

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Biological challenges and technological opportunities for respiratory syncytial virus vaccine development

Immunological reviews, 2011-01, Vol.239 (1), p.149-166

Graham, Barney S.

2011

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The role of Th17 and Treg responses in the pathogenesis of RSV infection

Pediatric research, 2015-11, Vol.78 (5), p.483-491

2015

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Cross-neutralization of four paramyxoviruses by a human monoclonal antibody

Nature (London), 2013-09, Vol.501 (7467), p.439-443

2013

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An Adjuvanted, Postfusion F Protein–Based Vaccine Did Not Prevent Respiratory Syncytial Virus Illness in Older Adults

The Journal of infectious diseases, 2017-12, Vol.216 (11), p.1362-1370

2017

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Investigational RSV Vaccine Given During Pregnancy Protects Newborns

JAMA : the journal of the American Medical Association, 2022-12, Vol.328 (22), p.2201

Larkin, Howard

2022

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Upper and lower respiratory tract correlates of protection against respiratory syncytial virus following vaccination of nonhuman primates

Cell host & microbe, 2022-01, Vol.30 (1), p.41-52.e5

2022

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Generation and Characterization of ALX-0171, a Potent Novel Therapeutic Nanobody for the Treatment of Respiratory Syncytial Virus Infection

Antimicrobial agents and chemotherapy, 2016-01, Vol.60 (1), p.6-13

2016

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Efficacy of a respiratory syncytial virus vaccine candidate in a maternal immunization model

Nature communications, 2018-05, Vol.9 (1), p.1904-10, Article 1904

2018

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A single, low dose of a cGMP recombinant BCG vaccine elicits protective T cell immunity against the human respiratory syncytial virus infection and prevents lung pathology in mice

Vaccine, 2017-02, Vol.35 (5), p.757-766

2017

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