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Overview of Determination of Biopharmaceutical Properties for Development Candidate Selection

Current protocols, 2023-11, Vol.3 (11), p.e926-n/a

Yazdanian, Mehran

2023

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Discovery and Characterization of 6-{4-[3-(R)-2-Methylpyrrolidin-1-yl)propoxy]phenyl}-2H-pyridazin-3-one (CEP-26401, Irdabisant): A Potent, Selective Histamine H3 Receptor Inverse Agonist

Journal of medicinal chemistry, 2011-07, Vol.54 (13), p.4781-4792

2011

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New directions in pharmaceutical amorphous materials and amorphous solid dispersions, a tribute to Professor George Zografi – Proceedings of the June 2016 Land O’Lakes Conference

AAPS open, 2017-08, Vol.3 (1), p.1-14, Article 7

2017

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Characterization of the Calu-3 cell line as a tool to screen pulmonary drug delivery

International journal of pharmaceutics, 2000-11, Vol.208 (1), p.1-11

2000

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Microparticulate uptake mechanisms of in-vitro cell culture models of the respiratory epithelium

Journal of pharmacy and pharmacology, 2001-01, Vol.53 (1), p.57-66

2001

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Evaluation of an accelerated Caco‐2 cell permeability model

Journal of pharmaceutical sciences, 2000-03, Vol.89 (3), p.336-345

2000

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Modulation of P-glycoprotein activity in Calu-3 cells using steroids and β-ligands

International journal of pharmaceutics, 2001-10, Vol.228 (1), p.171-179

2001

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Multidrug resistance-associated protein-1 functional activity in Calu-3 cells

The Journal of pharmacology and experimental therapeutics, 2001-09, Vol.298 (3), p.1199

2001

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Evolution of Choice of Solubility and Dissolution Media After Two Decades of Biopharmaceutical Classification System

The AAPS journal, 2017-07, Vol.19 (4), p.989-1001

2017

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Commentary: Why Pharmaceutical Scientists in Early Drug Discovery Are Critical for Influencing the Design and Selection of Optimal Drug Candidates

AAPS PharmSciTech, 2018, Vol.19 (1), p.1-10

2018

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Overview of Determination of Biopharmaceutical Properties for Development Candidate Selection

Current Protocols in Pharmacology, 2013-03, Vol.60 (1), p.9.17.1-9.17.8

Yazdanian, Mehran

2013

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Lipophilicity in Drug Development: Too Much or Not Enough?

The AAPS journal, 2016-09, Vol.18 (5), p.1095-1100

2016

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The effect of freezing on cattle skin permeability

International journal of pharmaceutics, 1994-02, Vol.103 (1), p.93-96

Yazdanian, Mehran

1994

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CEP-32496: a novel orally active BRAF(V600E) inhibitor with selective cellular and in vivo antitumor activity

Molecular cancer therapeutics, 2012-04, Vol.11 (4), p.930-941

2012

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Discovery and Characterization of 6-{4-[3-( R )-2-Methylpyrrolidin-1-yl)propoxy]phenyl}-2 H -pyridazin-3-one (CEP-26401, Irdabisant): A Potent, Selective Histamine H 3 Receptor Inverse Agonist

Journal of medicinal chemistry, 2011-07, Vol.54 (13), p.4781-4792

2011

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CEP-32496: A Novel Orally Active BRAFV600E Inhibitor with Selective Cellular and In Vivo Antitumor Activity

Molecular cancer therapeutics, 2012-04, Vol.11 (4), p.930-941

2012

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Early development GMPs for small-molecule specifications: an industry perspective (part v)

Pharmaceutical technology Europe, 2012-11, Vol.24 (11), p.26

2012

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Permeability measurement of macromolecules and assessment of mucosal antigen sampling using in vitro converted M cells

Journal of pharmacological and toxicological methods, 2001-09, Vol.46 (2), p.93-101

2001

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P-glycoprotein efflux pump expression and activity in Calu-3 cells

Journal of pharmaceutical sciences, 2001-05, Vol.90 (5), p.645

2001

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Nonpeptidic, monocharged, cell permeable ligands for the p561ck SH2 domain

Journal of medicinal chemistry, 2001, Vol.44 (15), p.2421-2431

2001

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An ellipsometric study of polymer monolayers at the air/water interface

Macromolecules, 1989-09, Vol.22 (5), p.2332-2337

1989

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Influence of Cationic Interactions on Fatty Acid Monolayers Studied by Ellipsometry

MRS proceedings, 1989, Vol.177, Article 405

1989

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Early development GMPs for small-molecule specifications: an industry perspective (Part V)

Pharmaceutical Technology, 2012-10, Vol.36 (10), p.86

2012

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Thin-Layer, Ph Sensitive Molecularly Imprinted Membranes for Selective Solid-Phase Extraction and Determination of Celecoxib in Biological Fluids

SSRN Electronic Journal

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Overview of Determination of Biopharmaceutical Properties for Development Candidate Selection

Discovery and Characterization of 6-{4-[3-(R)-2-Methylpyrrolidin-1-yl)propoxy]phenyl}-2H-pyridazin-3-one (CEP-26401, Irdabisant): A Potent, Selective Histamine H3 Receptor Inverse Agonist

New directions in pharmaceutical amorphous materials and amorphous solid dispersions, a tribute to Professor George Zografi – Proceedings of the June 2016 Land O’Lakes Conference

Characterization of the Calu-3 cell line as a tool to screen pulmonary drug delivery

Microparticulate uptake mechanisms of in-vitro cell culture models of the respiratory epithelium

Evaluation of an accelerated Caco‐2 cell permeability model

Modulation of P-glycoprotein activity in Calu-3 cells using steroids and β-ligands

Multidrug resistance-associated protein-1 functional activity in Calu-3 cells

Evolution of Choice of Solubility and Dissolution Media After Two Decades of Biopharmaceutical Classification System

Commentary: Why Pharmaceutical Scientists in Early Drug Discovery Are Critical for Influencing the Design and Selection of Optimal Drug Candidates

Overview of Determination of Biopharmaceutical Properties for Development Candidate Selection

Lipophilicity in Drug Development: Too Much or Not Enough?

The effect of freezing on cattle skin permeability

CEP-32496: a novel orally active BRAF(V600E) inhibitor with selective cellular and in vivo antitumor activity

Discovery and Characterization of 6-{4-[3-( R )-2-Methylpyrrolidin-1-yl)propoxy]phenyl}-2 H -pyridazin-3-one (CEP-26401, Irdabisant): A Potent, Selective Histamine H 3 Receptor Inverse Agonist

CEP-32496: A Novel Orally Active BRAFV600E Inhibitor with Selective Cellular and In Vivo Antitumor Activity

Early development GMPs for small-molecule specifications: an industry perspective (part v)

Permeability measurement of macromolecules and assessment of mucosal antigen sampling using in vitro converted M cells

P-glycoprotein efflux pump expression and activity in Calu-3 cells

Nonpeptidic, monocharged, cell permeable ligands for the p561ck SH2 domain

An ellipsometric study of polymer monolayers at the air/water interface

Influence of Cationic Interactions on Fatty Acid Monolayers Studied by Ellipsometry

Early development GMPs for small-molecule specifications: an industry perspective (Part V)

Thin-Layer, Ph Sensitive Molecularly Imprinted Membranes for Selective Solid-Phase Extraction and Determination of Celecoxib in Biological Fluids

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