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Lactate production is a prioritized feature of adipocyte metabolism

The Journal of biological chemistry, 2020-01, Vol.295 (1), p.83-98

2020

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Structure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors Targeting the ATP-binding Pocket

The Journal of biological chemistry, 2014-02, Vol.289 (7), p.4432-4443

2014

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Catalytic allylic oxidation of internal alkenes to a multifunctional chiral building block

Nature (London), 2017-07, Vol.547 (7662), p.196-200

2017

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Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain α-ketoacid dehydrogenase kinase

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (24), p.9728-9733

2013

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A new paradigm for GERD pathogenesis. Not acid injury, but cytokine-mediated inflammation driven by HIF-2α: a potential role for targeting HIF-2α to prevent and treat reflux esophagitis

Current opinion in pharmacology, 2017-12, Vol.37, p.93-99

2017

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Hypoxia-driven heterogeneous expression of α5 integrin in glioblastoma stem cells is linked to HIF-2α

Biochimica et biophysica acta. Molecular basis of disease, 2024-12, Vol.1870 (8), p.167471, Article 167471

2024

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Development of Inhibitors of the PAS‑B Domain of the HIF-2α Transcription Factor

Journal of medicinal chemistry, 2013-02, Vol.56 (4), p.1739-1747

2013

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Isoform-Selective and Stereoselective Inhibition of Hypoxia Inducible Factor‑2

Journal of medicinal chemistry, 2015-08, Vol.58 (15), p.5930-5941

2015

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Metabolic inflexibility promotes mitochondrial health during liver regeneration

Science (American Association for the Advancement of Science), 2024-06, Vol.384 (6701), p.eadj4301-eadj4301

2024

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Synthesis and Structural Characterization of Novel Trihalo-sulfone Inhibitors of WNK1

ACS medicinal chemistry letters, 2022-10, Vol.13 (10), p.1678-1684

2022

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Hypoxia-inducible factor-2α plays a role in mediating oesophagitis in GORD

Gut, 2017-09, Vol.66 (9), p.1542-1554

2017

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Benzothiophene Carboxylate Derivatives as Novel Allosteric Inhibitors of Branched-chain α-Ketoacid Dehydrogenase Kinase

The Journal of biological chemistry, 2014-07, Vol.289 (30), p.20583-20593

2014

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New advances in pericyclic reactions

Tetrahedron, 2017-07, Vol.73 (29), p.4009-4009

Tambar, Uttam K.

2017

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Copper-Catalyzed Enantioselective, Diastereoselective, and Regioselective [2,3]-Rearrangements of Iodonium Ylides

Angewandte Chemie International Edition, 2017-07, Vol.56 (33), p.9868-9871

2017

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Palladium-catalyzed cross-coupling of α-bromocarbonyls and allylic alcohols for the synthesis of α-aryl dicarbonyl compoundsElectronic supplementary information (ESI) available. CCDC 1042318. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5sc00505a

2015-04

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Abstract B037: Characterizing and targeting polyaneuploid/polyploid giant cancer cells (PACCs/PGCCs)

Cancer research (Chicago, Ill.), 2022-05, Vol.82 (10_Supplement), p.B037-B037

2022

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Hypoxia-Inducible Factor-2α Plays a Role in Mediating Oesophagitis in Gastro-Oesophageal Reflux Disease

Gut, 2016-09, Vol.66 (9), p.1542-1554

2016

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ChemInform Abstract: Regioselective and Diastereoselective Aminoarylation of 1,3-Dienes

ChemInform, 2015-04, Vol.46 (15), p.no-no

2015

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ChemInform Abstract: Allylic Functionalization of Unactivated Olefins with Grignard Reagents

ChemInform, 2014-08, Vol.45 (31), p.no-no

2014

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ChemInform Abstract: Catalytic Enantioselective Allylic Amination of Olefins for the Synthesis of ent-Sitagliptin

ChemInform, 2014-03, Vol.45 (12), p.no-no

2014

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ChemInform Abstract: Synthesis of (.+-.)-Amathaspiramide F (I) and Discovery of an Unusual Stereocontrolling Element for the [2,3]-Stevens Rearrangement

ChemInform, 2014-03, Vol.45 (10), p.no-no

2014

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ChemInform Abstract: Stereoselective Synthesis of Functionalized Cyclic Amino Acid Derivatives via a [2,3]-Stevens Rearrangement and Ring-Closing Metathesis

ChemInform, 2014-02, Vol.45 (6), p.no-no

2014

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ChemInform Abstract: Catalytic Enantioselective Allylic Amination of Unactivated Terminal Olefins via an Ene Reaction/[2,3]-Rearrangement

ChemInform, 2013-04, Vol.44 (17), p.no-no

2013

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ChemInform Abstract: Tandem Catalytic Allylic Amination and [2,3]-Stevens Rearrangement of Tertiary Amines

ChemInform, 2012-01, Vol.43 (4), p.no-no

2012

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Lactate production is a prioritized feature of adipocyte metabolism

The Journal of biological chemistry, 2020-01, Vol.295 (1), p.83

2020

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Lactate production is a prioritized feature of adipocyte metabolism

Structure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors Targeting the ATP-binding Pocket

Catalytic allylic oxidation of internal alkenes to a multifunctional chiral building block

Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain α-ketoacid dehydrogenase kinase

A new paradigm for GERD pathogenesis. Not acid injury, but cytokine-mediated inflammation driven by HIF-2α: a potential role for targeting HIF-2α to prevent and treat reflux esophagitis

Hypoxia-driven heterogeneous expression of α5 integrin in glioblastoma stem cells is linked to HIF-2α

Development of Inhibitors of the PAS‑B Domain of the HIF-2α Transcription Factor

Isoform-Selective and Stereoselective Inhibition of Hypoxia Inducible Factor‑2

Metabolic inflexibility promotes mitochondrial health during liver regeneration

Synthesis and Structural Characterization of Novel Trihalo-sulfone Inhibitors of WNK1

Hypoxia-inducible factor-2α plays a role in mediating oesophagitis in GORD

Benzothiophene Carboxylate Derivatives as Novel Allosteric Inhibitors of Branched-chain α-Ketoacid Dehydrogenase Kinase

New advances in pericyclic reactions

Copper-Catalyzed Enantioselective, Diastereoselective, and Regioselective [2,3]-Rearrangements of Iodonium Ylides

Palladium-catalyzed cross-coupling of α-bromocarbonyls and allylic alcohols for the synthesis of α-aryl dicarbonyl compoundsElectronic supplementary information (ESI) available. CCDC 1042318. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5sc00505a

Abstract B037: Characterizing and targeting polyaneuploid/polyploid giant cancer cells (PACCs/PGCCs)

Hypoxia-Inducible Factor-2α Plays a Role in Mediating Oesophagitis in Gastro-Oesophageal Reflux Disease

ChemInform Abstract: Regioselective and Diastereoselective Aminoarylation of 1,3-Dienes

ChemInform Abstract: Allylic Functionalization of Unactivated Olefins with Grignard Reagents

ChemInform Abstract: Catalytic Enantioselective Allylic Amination of Olefins for the Synthesis of ent-Sitagliptin

ChemInform Abstract: Synthesis of (.+-.)-Amathaspiramide F (I) and Discovery of an Unusual Stereocontrolling Element for the [2,3]-Stevens Rearrangement

ChemInform Abstract: Stereoselective Synthesis of Functionalized Cyclic Amino Acid Derivatives via a [2,3]-Stevens Rearrangement and Ring-Closing Metathesis

ChemInform Abstract: Catalytic Enantioselective Allylic Amination of Unactivated Terminal Olefins via an Ene Reaction/[2,3]-Rearrangement

ChemInform Abstract: Tandem Catalytic Allylic Amination and [2,3]-Stevens Rearrangement of Tertiary Amines

Lactate production is a prioritized feature of adipocyte metabolism

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