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Enantioselective Organocatalytic Construction of Pyrroloindolines by a Cascade Addition-Cyclization Strategy: Synthesis of (-)-Flustramine B

Proceedings of the National Academy of Sciences - PNAS, 2004-04, Vol.101 (15), p.5482-5487

2004

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Small molecule glucagon receptor antagonists: an updated patent review (2015-2019)

Expert opinion on therapeutic patents, 2020-07, Vol.30 (7), p.509-526

2020

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Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells

Molecular metabolism (Germany), 2013-11, Vol.2 (4), p.376-392

2013

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Discovery of Orally Bioavailable and Liver-Targeted Hypoxia-Inducible Factor Prolyl Hydroxylase (HIF-PHD) Inhibitors for the Treatment of Anemia

ACS medicinal chemistry letters, 2018-12, Vol.9 (12), p.1193-1198

2018

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Small molecule activation of lecithin cholesterol acyltransferase modulates lipoprotein metabolism in mice and hamsters

Metabolism, clinical and experimental, 2012-04, Vol.61 (4), p.470-481

2012

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Corrigendum to “Discovery of benzofuran propanoic acid GPR120 agonists: From uHTS hit to mechanism-based pharmacodynamic effects” [Bioorg. Med. Chem. Lett. 26 (2016) 5724–5728]

Bioorganic & medicinal chemistry letters, 2017-03, Vol.27 (5), p.1333-1333

2017

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Discovery and Optimization of a Novel Triazole Series of GPR142 Agonists for the Treatment of Type 2 Diabetes

ACS medicinal chemistry letters, 2016-12, Vol.7 (12), p.1107-1111

2016

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Abstract 17305: Activation of Soluble Guanylate Cyclase Ameliorates the Progression of Glucose Intolerance and Nephropathy in Obese ZSF1 Rats

Circulation (New York, N.Y.), 2016-11, Vol.134 (Suppl_1 Suppl 1), p.A17305-A17305

2016

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Total Synthesis of Dermostatin A

Angewandte Chemie, 2001-09, Vol.113 (17), p.3324-3327

2001

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Total Synthesis of Dermostatin A

Angewandte Chemie, 2001-09, Vol.113 (17), p.3324-3327

2001

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Total Synthesis of the Polyene Macrolide Dermostatin A

ChemInform, 2002-12, Vol.33 (50), p.204-204

2002

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ChemInform Abstract: 4-Acetoxy- and 4-Cyano-1,3-dioxanes in Synthesis

ChemInform, 2002-06, Vol.33 (24), p.no-no

2002

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ChemInform Abstract: Total Synthesis of Dermostatin A

ChemInform, 2001-12, Vol.32 (50), p.no-no

2001

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The Direct and Enantioselective Organocatalytic α-Oxidation of Aldehydes

ChemInform, 2004-01, Vol.35 (2), p.no-no

2004

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MZ-301 Is a Small Molecule Inhibitor of APOL1 Pore Function That Attenuates Albuminuria in a Mouse Model of APOL1-Mediated Kidney Disease: FR-PO318

Journal of the American Society of Nephrology, 2022-11, Vol.33 (11S), p.411-412

2022

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A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice

Nature medicine, 2014-08, Vol.20 (8), p.942-947

2014

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Metabolomic Profiling and Drug Interaction Characterization Reveal Riboflavin As a Breast Cancer Resistance Protein-Specific Endogenous Biomarker That Demonstrates Prediction of Transporter Activity In Vivo

Drug metabolism and disposition, 2023-07, Vol.51 (7), p.851-861

2023

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CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes

Drug metabolism and disposition, 2002-07, Vol.30 (7), p.795-804

2002

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Small Molecule Inhibition of APOL1 Reverses Albuminuria in a Chronic Mouse Model of APOL1-Mediated Kidney Disease: SA-PO788

Journal of the American Society of Nephrology, 2023-11, Vol.34 (11S), p.947-947

2023

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Small-molecule inhibition of glycogen synthase 1 for the treatment of Pompe disease and other glycogen storage disorders

Science translational medicine, 2024-01, Vol.16 (730), p.eadf1691

2024

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Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibition

Drug metabolism and disposition, 2003-04, Vol.31 (4), p.439-446

2003

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Small molecule inhibition of glycogen synthase 1 restores autophagolysosomal and metabolic pathway dysfunction in a mouse model of Pompe disease

Molecular genetics and metabolism, 2023-02, Vol.138 (2), p.107338, Article 107338

2023

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Substrate reduction therapy for Pompe disease: Small molecule inhibition of glycogen synthase 1 in preclinical models

Molecular genetics and metabolism, 2022-02, Vol.135 (2), p.S122-S122

2022

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Recent advances in drug transporter sciences: highlights from the year 2020

Drug metabolism reviews, 2021-07, Vol.53 (3), p.321-349

2021

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Enantioselective Organocatalytic Construction of Pyrroloindolines by a Cascade Addition-Cyclization Strategy: Synthesis of (-)-Flustramine B

Small molecule glucagon receptor antagonists: an updated patent review (2015-2019)

Design, Synthesis, and Evaluation of Novel and Selective G‑protein Coupled Receptor 120 (GPR120) Spirocyclic Agonists

Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells

Discovery of Orally Bioavailable and Liver-Targeted Hypoxia-Inducible Factor Prolyl Hydroxylase (HIF-PHD) Inhibitors for the Treatment of Anemia

Small molecule activation of lecithin cholesterol acyltransferase modulates lipoprotein metabolism in mice and hamsters

Corrigendum to “Discovery of benzofuran propanoic acid GPR120 agonists: From uHTS hit to mechanism-based pharmacodynamic effects” [Bioorg. Med. Chem. Lett. 26 (2016) 5724–5728]

Discovery and Optimization of a Novel Triazole Series of GPR142 Agonists for the Treatment of Type 2 Diabetes

Abstract 17305: Activation of Soluble Guanylate Cyclase Ameliorates the Progression of Glucose Intolerance and Nephropathy in Obese ZSF1 Rats

Total Synthesis of Dermostatin A

Total Synthesis of Dermostatin A

Total Synthesis of the Polyene Macrolide Dermostatin A

ChemInform Abstract: 4-Acetoxy- and 4-Cyano-1,3-dioxanes in Synthesis

ChemInform Abstract: Total Synthesis of Dermostatin A

The Direct and Enantioselective Organocatalytic α-Oxidation of Aldehydes

MZ-301 Is a Small Molecule Inhibitor of APOL1 Pore Function That Attenuates Albuminuria in a Mouse Model of APOL1-Mediated Kidney Disease: FR-PO318

A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice

Metabolomic Profiling and Drug Interaction Characterization Reveal Riboflavin As a Breast Cancer Resistance Protein-Specific Endogenous Biomarker That Demonstrates Prediction of Transporter Activity In Vivo

CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes

Small Molecule Inhibition of APOL1 Reverses Albuminuria in a Chronic Mouse Model of APOL1-Mediated Kidney Disease: SA-PO788

Small-molecule inhibition of glycogen synthase 1 for the treatment of Pompe disease and other glycogen storage disorders

Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibition

Small molecule inhibition of glycogen synthase 1 restores autophagolysosomal and metabolic pathway dysfunction in a mouse model of Pompe disease

Substrate reduction therapy for Pompe disease: Small molecule inhibition of glycogen synthase 1 in preclinical models

Recent advances in drug transporter sciences: highlights from the year 2020

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