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The SREBP pathway - insights from insigs and insects

Nature reviews. Molecular cell biology, 2003-08, Vol.4 (8), p.631-640

Rawson, Robert B

2003

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Health technology assessment and price negotiation alignment for rare disorder drugs in Canada: Who benefits?

Orphanet journal of rare diseases, 2022-06, Vol.17 (1), p.218-218, Article 218

Rawson, Nigel S B

2022

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Sleep targets highly connected global and local nodes to aid consolidation of learned graph networks

Scientific reports, 2022-09, Vol.12 (1), p.15086-15086, Article 15086

2022

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Is Canada Moving towards a More Agile Regulatory Approval and Reimbursement Process with a Shifting Role for Real-World Evidence (RWE) for Oncology Drugs?

Current oncology (Toronto), 2024-09, Vol.31 (9), p.5599-5607

2024

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National Pharmacare in Canada: Equality or Equity, Accessibility or Affordability Comment on "Universal Pharmacare in Canada: A Prescription for Equity in Healthcare"

International journal of health policy and management, 2020-12, Vol.9 (12), p.524-527

Rawson, Nigel S B

2020

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New Anticancer Drugs: Reliably Assessing "Value" While Addressing High Prices

Current oncology (Toronto), 2024-04, Vol.31 (5), p.2453-2480

2024

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ER Stress Induces Cleavage of Membrane-Bound ATF6 by the Same Proteases that Process SREBPs

Molecular cell, 2000-12, Vol.6 (6), p.1355-1364

2000

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Access to Oncology Medicines in Canada: Consensus Forum for Recommendations for Improvement

Current oncology (Toronto), 2024-04, Vol.31 (4), p.1803-1816

2024

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Leading Causes of Mortality and Prescription Drug Coverage in Canada and New Zealand

Frontiers in public health, 2020-10, Vol.8, p.544835-544835

Rawson, Nigel S B

2020

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The site-2 protease

Biochimica et biophysica acta, 2013-12, Vol.1828 (12), p.2801-2807

Rawson, Robert B.

2013

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Fatty acid auxotrophy in Drosophila larvae lacking SREBP

Cell metabolism, 2006-06, Vol.3 (6), p.439-448

2006

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COPI activity coupled with fatty acid biosynthesis is required for viral replication

PLoS pathogens, 2006-10, Vol.2 (10), p.e102-e102

2006

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Regulation of SREBP Processing and Membrane Lipid Production by Phospholipids in Drosophila

Science (American Association for the Advancement of Science), 2002-05, Vol.296 (5569), p.879-883

2002

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Mutant Mammalian Cells as Tools to Delineate the Sterol Regulatory Element-Binding Protein Pathway for Feedback Regulation of Lipid Synthesis

Archives of Biochemistry and Biophysics, 2002-01, Vol.397 (2), p.139-148

2002

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Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

Cell, 2000-02, Vol.100 (4), p.391-398

2000

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Dual Roles for Cholesterol in Mammalian Cells

Proceedings of the National Academy of Sciences - PNAS, 2005-10, Vol.102 (41), p.14551-14556

2005

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Promoting adherence to medicines: possible lessons for Canada?

Israel journal of health policy research, 2017-11, Vol.6 (1), p.63-63, Article 63

Rawson, Nigel S B

2017

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Ex vivo comparison of V.A.C.® Granufoam Silver™ and V.A.C.® Granufoam™ loaded with a first-in-class bis-dialkylnorspermidine-terphenyl antibiofilm agent

Biofilm, 2023-12, Vol.6, p.100142-100142, Article 100142

2023

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Drug safety: withdrawn medications are only part of the picture

BMC medicine, 2016-02, Vol.14 (28), p.28-28, Article 28

Rawson, Nigel S B

2016

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The impact of willingness-to-pay threshold on price reduction recommendations for oncology drugs: a review of assessments conducted by the Canadian Agency for Drugs and Technologies in Health

Journal of comparative effectiveness research, 2024-05, Vol.13 (5), p.e230178-e230178

2024

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The SREBP Pathway in Drosophila: Regulation by Palmitate, Not Sterols

Developmental cell, 2002-02, Vol.2 (2), p.229-238

2002

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Promoter methylation of Wnt5a is associated with microsatellite instability and BRAF V600E mutation in two large populations of colorectal cancer patients

British journal of cancer, 2011-06, Vol.104 (12), p.1906-1912

2011

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Three Mutations in Sterol-Sensing Domain of SCAP Block Interaction with Insig and Render SREBP Cleavage Insensitive to Sterols

Proceedings of the National Academy of Sciences - PNAS, 2002-12, Vol.99 (26), p.16672-16677

2002

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Molecular Identification of the Sterol-Regulated Luminal Protease that Cleaves SREBPs and Controls Lipid Composition of Animal Cells

Molecular cell, 1998-10, Vol.2 (4), p.505-514

1998

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Sterol-Regulated Release of SREBP-2 from Cell Membranes Requires Two Sequential Cleavages, One Within a Transmembrane Segment

Cell, 1996-06, Vol.85 (7), p.1037-1046

1996

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The SREBP pathway - insights from insigs and insects

Health technology assessment and price negotiation alignment for rare disorder drugs in Canada: Who benefits?

Sleep targets highly connected global and local nodes to aid consolidation of learned graph networks

Is Canada Moving towards a More Agile Regulatory Approval and Reimbursement Process with a Shifting Role for Real-World Evidence (RWE) for Oncology Drugs?

National Pharmacare in Canada: Equality or Equity, Accessibility or Affordability Comment on "Universal Pharmacare in Canada: A Prescription for Equity in Healthcare"

New Anticancer Drugs: Reliably Assessing "Value" While Addressing High Prices

ER Stress Induces Cleavage of Membrane-Bound ATF6 by the Same Proteases that Process SREBPs

Access to Oncology Medicines in Canada: Consensus Forum for Recommendations for Improvement

Leading Causes of Mortality and Prescription Drug Coverage in Canada and New Zealand

The site-2 protease

Fatty acid auxotrophy in Drosophila larvae lacking SREBP

COPI activity coupled with fatty acid biosynthesis is required for viral replication

Regulation of SREBP Processing and Membrane Lipid Production by Phospholipids in Drosophila

Mutant Mammalian Cells as Tools to Delineate the Sterol Regulatory Element-Binding Protein Pathway for Feedback Regulation of Lipid Synthesis

Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

Dual Roles for Cholesterol in Mammalian Cells

Promoting adherence to medicines: possible lessons for Canada?

Ex vivo comparison of V.A.C.® Granufoam Silver™ and V.A.C.® Granufoam™ loaded with a first-in-class bis-dialkylnorspermidine-terphenyl antibiofilm agent

Drug safety: withdrawn medications are only part of the picture

The impact of willingness-to-pay threshold on price reduction recommendations for oncology drugs: a review of assessments conducted by the Canadian Agency for Drugs and Technologies in Health

The SREBP Pathway in Drosophila: Regulation by Palmitate, Not Sterols

Promoter methylation of Wnt5a is associated with microsatellite instability and BRAF V600E mutation in two large populations of colorectal cancer patients

Three Mutations in Sterol-Sensing Domain of SCAP Block Interaction with Insig and Render SREBP Cleavage Insensitive to Sterols

Molecular Identification of the Sterol-Regulated Luminal Protease that Cleaves SREBPs and Controls Lipid Composition of Animal Cells

Sterol-Regulated Release of SREBP-2 from Cell Membranes Requires Two Sequential Cleavages, One Within a Transmembrane Segment

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