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The potential health effects of dietary phytoestrogens

British journal of pharmacology, 2017-06, Vol.174 (11), p.1263-1280

2017

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Studying the metabolic functionality of the intestinal microbiota in vitro

Toxicology letters, 2017-10, Vol.280, p.S12-S12

Beekmann, Karsten

2017

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An in vitromodel to quantify interspecies differences in kinetics for intestinal microbial bioactivation and detoxification of zearalenone

Toxicology reports, 2020-01, Vol.7, p.938-946

2020

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Determination of in vitro immunotoxic potencies of a series of perfluoralkylsubstances (PFASs) in human Namalwa B lymphocyte and human Jurkat T lymphocyte cells

Frontiers in toxicology, 2024-03, Vol.6, p.1347965-1347965

2024

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The effect of quercetin and kaempferol aglycones and glucuronides on peroxisome proliferator-activated receptor-gamma (PPAR-γ)

Food & function, 2015-04, Vol.6 (4), p.198-117

2015

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A state-of-the-art overview of the effect of metabolic conjugation on the biological activity of flavonoids

Food & function, 2012, Vol.3 (1), p.18-118

2012

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Antibiotic-Induced Changes in Microbiome-Related Metabolites and Bile Acids in Rat Plasma

Metabolites, 2020-06, Vol.10 (6), p.242

2020

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Physiologically based kinetic (PBK) modeling as a new approach methodology (NAM) for predicting systemic levels of gut microbial metabolites

Toxicology letters, 2024-05, Vol.396, p.94-102

2024

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Physiologically‐Based Pharmacokinetic Modeling of the Postbiotic Supplement Urolithin A Predicts its Bioavailability Is Orders of Magnitude Lower than Concentrations that Induce Toxicity, but also Neuroprotective Effects

Molecular nutrition & food research, 2023-08, Vol.67 (15), p.e2300009-n/a

2023

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Interaction between food-borne mycotoxins and gut microbiota: A review

Food control, 2021-08, Vol.126, p.107998, Article 107998

2021

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Differences in kinetics and dynamics of endogenous versus exogenous advanced glycation end products (AGEs) and their precursors

Food and chemical toxicology, 2022-06, Vol.164, p.112987-112987, Article 112987

2022

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Use of Physiologically Based Kinetic Modeling to Predict Rat Gut Microbial Metabolism of the Isoflavone Daidzein to S‐Equol and Its Consequences for ERα Activation

Molecular nutrition & food research, 2020-03, Vol.64 (6), p.e1900912-n/a

2020

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Front Cover: Use of Physiologically Based Kinetic Modeling to Predict Rat Gut Microbial Metabolism of the Isoflavone Daidzein to S‐Equol and Its Consequences for ERα Activation

Molecular nutrition & food research, 2020-03, Vol.64 (6), p.n/a

2020

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Inside Front Cover: Species Differences in in vitro and Estimated in vivo Kinetics for Intestinal Microbiota Mediated Metabolism of Acetyl‐deoxynivalenols

Molecular nutrition & food research, 2021-05, Vol.65 (9), p.n/a

2021

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Species Differences in in vitro and Estimated in vivo Kinetics for Intestinal Microbiota Mediated Metabolism of Acetyl‐deoxynivalenols

Molecular nutrition & food research, 2021-05, Vol.65 (9), p.e2001085-n/a

2021

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Interindividual Differences in Human In Vitro Intestinal Microbial Conversion of Green Tea (‐)‐Epigallocatechin‐3‐O‐Gallate and Consequences for Activation of Nrf2 Mediated Gene Expression

Molecular nutrition & food research, 2021-01, Vol.65 (2), p.n/a

2021

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Perfluoroalkyl substances (PFASs) decrease the expression of recombination-activating genes (RAG1 and RAG2) in human B lymphoma Namalwa cells

Archives of toxicology, 2023-02, Vol.97 (2), p.457-468

2023

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An in vitro model for microbial fructoselysine degradation shows substantial interindividual differences in metabolic capacities of human fecal slurries

Toxicology in vitro, 2021-04, Vol.72, p.105078, Article 105078

2021

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Combining In Vitro Data and Physiologically Based Kinetic Modeling Facilitates Reverse Dosimetry to Define In Vivo Dose–Response Curves for Bixin‐ and Crocetin‐Induced Activation of PPARγ in Humans

Molecular nutrition & food research, 2020-01, Vol.64 (2), p.e1900880-n/a

2020

Volltextzugriff (PDF)

Predictive performance of next generation human physiologically based kinetic (PBK) models based on in vitro and in silico input data

ALTEX, alternatives to animal experimentation, 2022-03, Vol.39 (2), p.221–234-221–234

2022

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Use of proteomics to detect sex-related differences in effects of toxicants: implications for using proteomics in toxicology

Critical reviews in toxicology, 2018-09, Vol.48 (8), p.666-681

2018

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In vitro bioassays to evaluate beneficial and adverse health effects of botanicals: promises and pitfalls

Drug discovery today, 2017-08, Vol.22 (8), p.1187-1200

2017

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The effect of glucuronidation on isoflavone induced estrogen receptor (ER)α and ERβ mediated coregulator interactions

The Journal of steroid biochemistry and molecular biology, 2015-11, Vol.154, p.245-253

2015

Volltextzugriff (PDF)

The Influence of Phase II Conjugation on the Biological Activity of Flavonoids

Beekmann, Karsten

2016

Volltextzugriff (PDF)

Collection of human and environmental data on pesticide use in Europe and Argentina: Field study protocol for the SPRINT project

PloS one, 2021-01, Vol.16 (11)

2021

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The potential health effects of dietary phytoestrogens

Studying the metabolic functionality of the intestinal microbiota in vitro

An in vitromodel to quantify interspecies differences in kinetics for intestinal microbial bioactivation and detoxification of zearalenone

Determination of in vitro immunotoxic potencies of a series of perfluoralkylsubstances (PFASs) in human Namalwa B lymphocyte and human Jurkat T lymphocyte cells

The effect of quercetin and kaempferol aglycones and glucuronides on peroxisome proliferator-activated receptor-gamma (PPAR-γ)

A state-of-the-art overview of the effect of metabolic conjugation on the biological activity of flavonoids

Antibiotic-Induced Changes in Microbiome-Related Metabolites and Bile Acids in Rat Plasma

Physiologically based kinetic (PBK) modeling as a new approach methodology (NAM) for predicting systemic levels of gut microbial metabolites

Physiologically‐Based Pharmacokinetic Modeling of the Postbiotic Supplement Urolithin A Predicts its Bioavailability Is Orders of Magnitude Lower than Concentrations that Induce Toxicity, but also Neuroprotective Effects

Interaction between food-borne mycotoxins and gut microbiota: A review

Differences in kinetics and dynamics of endogenous versus exogenous advanced glycation end products (AGEs) and their precursors

Use of Physiologically Based Kinetic Modeling to Predict Rat Gut Microbial Metabolism of the Isoflavone Daidzein to S‐Equol and Its Consequences for ERα Activation

Front Cover: Use of Physiologically Based Kinetic Modeling to Predict Rat Gut Microbial Metabolism of the Isoflavone Daidzein to S‐Equol and Its Consequences for ERα Activation

Inside Front Cover: Species Differences in in vitro and Estimated in vivo Kinetics for Intestinal Microbiota Mediated Metabolism of Acetyl‐deoxynivalenols

Species Differences in in vitro and Estimated in vivo Kinetics for Intestinal Microbiota Mediated Metabolism of Acetyl‐deoxynivalenols

Interindividual Differences in Human In Vitro Intestinal Microbial Conversion of Green Tea (‐)‐Epigallocatechin‐3‐O‐Gallate and Consequences for Activation of Nrf2 Mediated Gene Expression

Perfluoroalkyl substances (PFASs) decrease the expression of recombination-activating genes (RAG1 and RAG2) in human B lymphoma Namalwa cells

An in vitro model for microbial fructoselysine degradation shows substantial interindividual differences in metabolic capacities of human fecal slurries

Combining In Vitro Data and Physiologically Based Kinetic Modeling Facilitates Reverse Dosimetry to Define In Vivo Dose–Response Curves for Bixin‐ and Crocetin‐Induced Activation of PPARγ in Humans

Predictive performance of next generation human physiologically based kinetic (PBK) models based on in vitro and in silico input data

Use of proteomics to detect sex-related differences in effects of toxicants: implications for using proteomics in toxicology

In vitro bioassays to evaluate beneficial and adverse health effects of botanicals: promises and pitfalls

The effect of glucuronidation on isoflavone induced estrogen receptor (ER)α and ERβ mediated coregulator interactions

The Influence of Phase II Conjugation on the Biological Activity of Flavonoids

Collection of human and environmental data on pesticide use in Europe and Argentina: Field study protocol for the SPRINT project

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