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Drug Selectivity: An Evolving Concept in Medicinal Chemistry

1, 2018

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Resveratrol post-transcriptionally regulates pro-inflammatory gene expression via regulation of KSRP RNA binding activity

Nucleic acids research, 2014-11, Vol.42 (20), p.12555-12569

2014

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The quality of drugs and drug products - Always guaranteed?

Journal of pharmaceutical and biomedical analysis, 2024-02, Vol.239, p.115880-115880, Article 115880

2024

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Antioxidant activity of resveratrol, piceatannol and 3,3',4,4',5,5'-hexahydroxy-trans-stilbene in three leukemia cell lines

Oncology reports, 2006-09, Vol.16 (3), p.617-624

2006

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Strategy to Assess and Control Nitrosamine Formation in API during Storage: A Sitagliptin Case Study

Organic process research & development, 2024-08, Vol.28 (8), p.3182-3196

2024

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Prediction of Degradation Profiles for Various Sartans under Solvent-Free Mechanochemical Conditions

Analytical chemistry (Washington), 2024-08, Vol.96 (32), p.13166-13173

2024

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Novel Resveratrol Derivatives Induce Apoptosis and Cause Cell Cycle Arrest in Prostate Cancer Cell Lines

Anticancer research, 2007-09, Vol.27 (5A), p.3459-3464

2007

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New approaches to treating pain

Bioorganic & medicinal chemistry letters, 2016-02, Vol.26 (4), p.1103-1119

2016

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Antioxidant, prooxidant and cytotoxic activity of hydroxylated resveratrol analogues: structure–activity relationship

Biochemical pharmacology, 2005-03, Vol.69 (6), p.903-912

2005

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Synthesis of Novel Curcumin Analogues and Their Evaluation as Selective Cyclooxygenase-1 (COX-1) Inhibitors

Chemical & Pharmaceutical Bulletin, 2007, Vol.55 (1), p.64-71

2007

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Resveratrol analogues as selective cyclooxygenase-2 inhibitors: synthesis and structure–activity relationship

Bioorganic & medicinal chemistry, 2004-11, Vol.12 (21), p.5571-5578

2004

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Antiproliferative and Pro-apoptotic Activities of a Novel Resveratrol Prodrug Against Jurkat CD4+ T-Cells

Anticancer research, 2016-02, Vol.36 (2), p.683

2016

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Drug Selectivity

2017

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A tetracyclic thiophene trimer synthesis and mechanism of formation

Tetrahedron letters, 2013-05, Vol.54 (21), p.2696-2698

2013

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A Novel Genistein Prodrug: Design, Synthesis and Bioactivity on Mouse RAW264.7 Macrophages

Natural product communications, 2016-10, Vol.11 (10), p.1437-1440

2016

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‘Bridged’ stilbene derivatives as selective cyclooxygenase-1 inhibitors

Bioorganic & medicinal chemistry, 2007-09, Vol.15 (18), p.6109-6118

2007

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Cytotoxic and biochemical effects of 3,3′,4,4′,5,5′-hexahydroxystilbene, a novel resveratrol analog in HL-60 human promyelocytic leukemia cells

Experimental hematology, 2006-10, Vol.34 (10), p.1377-1384

2006

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Novel resveratrol analogs induce apoptosis and cause cell cycle arrest in HT29 human colon cancer cells : Inhibition of ribonucleotide reductase activity

Oncology reports, 2008-06, Vol.19 (6), p.1621-1626

2008

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Benzanilides with spasmolytic activity: Chemistry, pharmacology, and SAR

Bioorganic & medicinal chemistry, 2008-06, Vol.16 (11), p.5974-5981

2008

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No evidence for modulation of endothelial nitric oxide synthase by the olive oil polyphenol hydroxytyrosol in human endothelial cells

Atherosclerosis, 2007-11, Vol.195 (1), p.e58-e64

2007

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Antitumor effects of KITC, a new resveratrol derivative, in AsPC-1 and BxPC-3 human pancreatic carcinoma cells

Investigational new drugs, 2009-10, Vol.27 (5), p.393-401

2009

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Completion of the Spectroscopical Data for the Synthesis of DIMBOA

Scientia pharmaceutica, 2005-09, Vol.73 (3), p.95-100

2005

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Synthesis of Nitrated Thienylphosphonates via Michaelis-Arbuzov-Type Rearrangement

Synthesis (Stuttgart), 2004-04, Vol.2004 (5), p.668-670

2004

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Pharmacophore Generation for Multiple Ligands

Drug Selectivity, 2017, p.275-312

2017

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N-hydroxy-N'-(3,4,5-trimethoxyphenyl)-3,4,5-trimethoxy-benzamidine, a novel resveratrol analog, inhibits ribonucleotide reductase in HL-60 human promyelocytic leukemia cells: synergistic antitumor activity with arabinofuranosylcytosine

International journal of oncology, 2007-11, Vol.31 (5), p.1261

2007

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Drug Selectivity: An Evolving Concept in Medicinal Chemistry

Resveratrol post-transcriptionally regulates pro-inflammatory gene expression via regulation of KSRP RNA binding activity

The quality of drugs and drug products - Always guaranteed?

Antioxidant activity of resveratrol, piceatannol and 3,3',4,4',5,5'-hexahydroxy-trans-stilbene in three leukemia cell lines

Strategy to Assess and Control Nitrosamine Formation in API during Storage: A Sitagliptin Case Study

Prediction of Degradation Profiles for Various Sartans under Solvent-Free Mechanochemical Conditions

Novel Resveratrol Derivatives Induce Apoptosis and Cause Cell Cycle Arrest in Prostate Cancer Cell Lines

New approaches to treating pain

Antioxidant, prooxidant and cytotoxic activity of hydroxylated resveratrol analogues: structure–activity relationship

Synthesis of Novel Curcumin Analogues and Their Evaluation as Selective Cyclooxygenase-1 (COX-1) Inhibitors

Resveratrol analogues as selective cyclooxygenase-2 inhibitors: synthesis and structure–activity relationship

Antiproliferative and Pro-apoptotic Activities of a Novel Resveratrol Prodrug Against Jurkat CD4+ T-Cells

Drug Selectivity

A tetracyclic thiophene trimer synthesis and mechanism of formation

A Novel Genistein Prodrug: Design, Synthesis and Bioactivity on Mouse RAW264.7 Macrophages

‘Bridged’ stilbene derivatives as selective cyclooxygenase-1 inhibitors

Cytotoxic and biochemical effects of 3,3′,4,4′,5,5′-hexahydroxystilbene, a novel resveratrol analog in HL-60 human promyelocytic leukemia cells

Novel resveratrol analogs induce apoptosis and cause cell cycle arrest in HT29 human colon cancer cells : Inhibition of ribonucleotide reductase activity

Benzanilides with spasmolytic activity: Chemistry, pharmacology, and SAR

No evidence for modulation of endothelial nitric oxide synthase by the olive oil polyphenol hydroxytyrosol in human endothelial cells

Antitumor effects of KITC, a new resveratrol derivative, in AsPC-1 and BxPC-3 human pancreatic carcinoma cells

Completion of the Spectroscopical Data for the Synthesis of DIMBOA

Synthesis of Nitrated Thienylphosphonates via Michaelis-Arbuzov-Type Rearrangement

Pharmacophore Generation for Multiple Ligands

N-hydroxy-N'-(3,4,5-trimethoxyphenyl)-3,4,5-trimethoxy-benzamidine, a novel resveratrol analog, inhibits ribonucleotide reductase in HL-60 human promyelocytic leukemia cells: synergistic antitumor activity with arabinofuranosylcytosine

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