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New compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites: an open resource

Scientific reports, 2015-03, Vol.5 (1), p.8771-8771, Article 8771

2015

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Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides

Journal of medicinal chemistry, 2016-11, Vol.59 (21), p.9686-9720

2016

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Positive and Negative Allosteric Modulators of the Ca2+-sensing Receptor Interact within Overlapping but Not Identical Binding Sites in the Transmembrane Domain

The Journal of biological chemistry, 2004-04, Vol.279 (18), p.18990-18997

2004

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Modeling and Mutagenesis of the Binding Site of Calhex 231, a Novel Negative Allosteric Modulator of the Extracellular Ca2+-sensing Receptor

The Journal of biological chemistry, 2003-12, Vol.278 (49), p.49487-49494

2003

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A novel class of fast‐acting antimalarial agents: Substituted 15‐membered azalides

British journal of pharmacology, 2021-01, Vol.178 (2), p.363-377

2021

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Discovery of Potent N‑Ethylurea Pyrazole Derivatives as Dual Inhibitors of Trypanosoma brucei and Trypanosoma cruzi

ACS medicinal chemistry letters, 2020-03, Vol.11 (3), p.278-285

2020

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Modeling and mutagenesis of the binding site of Calhex 231, a novel negative allosteric modulator of the extracellular Ca(2+)-sensing receptor

The Journal of biological chemistry, 2003-12, Vol.278 (49), p.49487-94

2003

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The Qi Site of Cytochrome b is a Promiscuous Drug Target in Trypanosoma cruzi and Leishmania donovani

ACS infectious diseases, 2020-03, Vol.6 (3), p.515-528

2020

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N -Benzoyl-N -[1-(1-naphthyl)ethyl]-trans-1,2-diaminocyclohexanes: Development of 4-Chlorophenylcarboxamide (Calhex 231) as a New Calcium Sensing Receptor Ligand Demonstrating Potent Calcilytic Activity

Journal of medicinal chemistry, 2006-08, Vol.49 (17), p.5119-5128

2006

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Rose Bengal analogs and vesicular glutamate transporters (VGLUTs)

Bioorganic & medicinal chemistry, 2010-09, Vol.18 (18), p.6922-6933

2010

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Indole Synthesis by Controlled Carbolithiation of o-Aminostyrenes

Journal of organic chemistry, 2004-11, Vol.69 (23), p.7836-7846

2004

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Molecular Tongs Containing Amino Acid Mimetic Fragments: New Inhibitors of Wild-Type and Mutated HIV-1 Protease Dimerization

Journal of medicinal chemistry, 2006-07, Vol.49 (15), p.4657-4664

2006

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Cyclopropyl Carboxamides: A New Oral Antimalarial Series Derived from the Tres Cantos Anti-Malarial Set (TCAMS)

ACS medicinal chemistry letters, 2011-11, Vol.2 (11), p.840-844

2011

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N(1)-Arylsulfonyl-N(2)-(1-(1-naphthyl)ethyl)-1,2-diaminocyclohexanes: a new class of calcilytic agents acting at the calcium-sensing receptor

Chembiochem : a European journal of chemical biology, 2004-08, Vol.5 (8), p.1131-1136

2004

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N 1 ‐Arylsulfonyl‐ N 2 ‐(1‐(1‐naphthyl)ethyl)‐1,2‐diaminocyclohexanes: A New Class of Calcilytic Agents Acting at the Calcium‐Sensing Receptor

Chembiochem : a European journal of chemical biology, 2004-08, Vol.5 (8), p.1131-1136

2004

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N1-benzoyl-N2-[1-(1-naphthyl)ethyl]-trans-1,2-diaminocyclohexanes : Development of 4-chlorophenylcarboxamide (Calhex 231) as a new calcium sensing receptor ligand demonstrating potent calcilytic activity

Journal of medicinal chemistry, 2006-08, Vol.49 (17), p.5119-5128

2006

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Molecular determinants of allosteric modulators of the calcium-sensing receptor

Journal of physiology, Paris, 2006-03, Vol.99 (2), p.2-3

2006

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N2-Benzyl- N1-(1-(1-naphthyl)ethyl)-3-phenylpropane-1,2-diamines and conformationally restrained indole analogues: development of calindol as a new calcimimetic acting at the calcium sensing receptor

Bioorganic & medicinal chemistry letters, 2004-06, Vol.14 (12), p.3345-3349

2004

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N1-Arylsulfonyl-N2-(1-(1-naphthyl)ethyl)-1,2-diaminocyclohexanes: A New Class of Calcilytic Agents Acting at the Calcium-Sensing Receptor

Chembiochem : a European journal of chemical biology, 2004-08, Vol.5 (8), p.1131-1136

2004

Volltextzugriff (PDF)

N super(1)-Arylsulfonyl-N super(2)-(1-(1-naphthyl)ethyl)-1,2-diaminocyclohexanes: A New Class of Calcilytic Agents Acting at the Calcium-Sensing Receptor

Chembiochem : a European journal of chemical biology, 2004-01, Vol.5 (8), p.1131-1136

2004

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SUZUKI-MIYAURA CROSS-COUPLING: PREPARATION OF 2'-VINYLACETANILIDE

Organic syntheses, 2006, Vol.83, p.45

2006

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Indole Synthesis by Controlled Carbolithiation of o-Aminostyrenes

ChemInform, 2005-03, Vol.36 (12), p.no-no

2005

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Indole Synthesis by Controlled Carbolithiation of o-Aminostyrenes

ChemInform, 2005-03, Vol.36 (12), p.no-no

2005

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N 2 ‐Benzyl‐N 1 ‐(1‐ (1‐naphthyl)ethyl)‐3‐phenylpropane‐1,2‐diamines and Conformationally Restrained Indole Analogues: Development of Calindol as a New Calcimimetic Acting at the Calcium Sensing Receptor

ChemInform, 2004-10, Vol.35 (42)

2004

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N2-Benzyl-N1-(1- (1-naphthyl)ethyl)-3-phenylpropane-1,2-diamines and Conformationally Restrained Indole Analogues: Development of Calindol as a New Calcimimetic Acting at the Calcium Sensing Receptor

ChemInform, 2004-10, Vol.35 (42), p.no-no

2004

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New compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites: an open resource

Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides

Positive and Negative Allosteric Modulators of the Ca2+-sensing Receptor Interact within Overlapping but Not Identical Binding Sites in the Transmembrane Domain

Modeling and Mutagenesis of the Binding Site of Calhex 231, a Novel Negative Allosteric Modulator of the Extracellular Ca2+-sensing Receptor

A novel class of fast‐acting antimalarial agents: Substituted 15‐membered azalides

Discovery of Potent N‑Ethylurea Pyrazole Derivatives as Dual Inhibitors of Trypanosoma brucei and Trypanosoma cruzi

Modeling and mutagenesis of the binding site of Calhex 231, a novel negative allosteric modulator of the extracellular Ca(2+)-sensing receptor

The Qi Site of Cytochrome b is a Promiscuous Drug Target in Trypanosoma cruzi and Leishmania donovani

N -Benzoyl-N -[1-(1-naphthyl)ethyl]-trans-1,2-diaminocyclohexanes: Development of 4-Chlorophenylcarboxamide (Calhex 231) as a New Calcium Sensing Receptor Ligand Demonstrating Potent Calcilytic Activity

Rose Bengal analogs and vesicular glutamate transporters (VGLUTs)

Indole Synthesis by Controlled Carbolithiation of o-Aminostyrenes

Molecular Tongs Containing Amino Acid Mimetic Fragments: New Inhibitors of Wild-Type and Mutated HIV-1 Protease Dimerization

Cyclopropyl Carboxamides: A New Oral Antimalarial Series Derived from the Tres Cantos Anti-Malarial Set (TCAMS)

N(1)-Arylsulfonyl-N(2)-(1-(1-naphthyl)ethyl)-1,2-diaminocyclohexanes: a new class of calcilytic agents acting at the calcium-sensing receptor

N 1 ‐Arylsulfonyl‐ N 2 ‐(1‐(1‐naphthyl)ethyl)‐1,2‐diaminocyclohexanes: A New Class of Calcilytic Agents Acting at the Calcium‐Sensing Receptor

N1-benzoyl-N2-[1-(1-naphthyl)ethyl]-trans-1,2-diaminocyclohexanes : Development of 4-chlorophenylcarboxamide (Calhex 231) as a new calcium sensing receptor ligand demonstrating potent calcilytic activity

Molecular determinants of allosteric modulators of the calcium-sensing receptor

N2-Benzyl- N1-(1-(1-naphthyl)ethyl)-3-phenylpropane-1,2-diamines and conformationally restrained indole analogues: development of calindol as a new calcimimetic acting at the calcium sensing receptor

N1-Arylsulfonyl-N2-(1-(1-naphthyl)ethyl)-1,2-diaminocyclohexanes: A New Class of Calcilytic Agents Acting at the Calcium-Sensing Receptor

N super(1)-Arylsulfonyl-N super(2)-(1-(1-naphthyl)ethyl)-1,2-diaminocyclohexanes: A New Class of Calcilytic Agents Acting at the Calcium-Sensing Receptor

SUZUKI-MIYAURA CROSS-COUPLING: PREPARATION OF 2'-VINYLACETANILIDE

Indole Synthesis by Controlled Carbolithiation of o-Aminostyrenes

Indole Synthesis by Controlled Carbolithiation of o-Aminostyrenes

N 2 ‐Benzyl‐N 1 ‐(1‐ (1‐naphthyl)ethyl)‐3‐phenylpropane‐1,2‐diamines and Conformationally Restrained Indole Analogues: Development of Calindol as a New Calcimimetic Acting at the Calcium Sensing Receptor

N2-Benzyl-N1-(1- (1-naphthyl)ethyl)-3-phenylpropane-1,2-diamines and Conformationally Restrained Indole Analogues: Development of Calindol as a New Calcimimetic Acting at the Calcium Sensing Receptor

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