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Pushing Forward the Future Tense: Perspectives of a Scientist

Annual review of pharmacology and toxicology, 2022-01, Vol.62 (1), p.1-18

Limbird, Lee E.

2022

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Estradiol-mediated ERK phosphorylation and apoptosis in vascular smooth muscle cells requires GPR 30

American Journal of Physiology: Cell Physiology, 2009-11, Vol.297 (5), p.C1178-C1187

2009

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Correlation of functional and radioligand binding characteristics of GPER ligands confirming aldosterone as a GPER agonist

Pharmacology research & perspectives, 2022-10, Vol.10 (5), p.e00995-n/a

2022

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GPER (GPR30): A Nongenomic Receptor (GPCR) for Steroid Hormones with Implications for Cardiovascular Disease and Cancer

Annual review of pharmacology and toxicology, 2017-01, Vol.57 (1), p.567-584

2017

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G protein-coupled receptor interacting proteins: Emerging roles in localization and signal transduction

Cellular signalling, 2002-04, Vol.14 (4), p.297-309

2002

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Deubiquitination of CXCR4 by USP14 Is Critical for Both CXCL12-induced CXCR4 Degradation and Chemotaxis but Not ERK Activation

The Journal of biological chemistry, 2009-02, Vol.284 (9), p.5742-5752

2009

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Adenylyl Cyclase Isoform–Selective Regulation of Vascular Smooth Muscle Proliferation and Cytoskeletal Reorganization

Circulation research, 2006-10, Vol.99 (8), p.845-852

2006

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Aldosterone mediates metastatic spread of renal cancer via the G protein‐coupled estrogen receptor (GPER)

The FASEB journal, 2016-06, Vol.30 (6), p.2086-2096

2016

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Copernicus Revisited: Overturning Ptolemy's View of the GPER Universe

Trends in endocrinology and metabolism, 2015-11, Vol.26 (11), p.592-594

2015

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Appropriate Polarization following Pharmacological Rescue of V2 Vasopressin Receptors Encoded by X-linked Nephrogenic Diabetes Insipidus Alleles Involves a Conformation of the Receptor That Also Attains Mature Glycosylation

The Journal of biological chemistry, 2003-09, Vol.278 (37), p.35678-35686

2003

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The Receptor Concept: A Continuing Evolution

Molecular interventions, 2004-12, Vol.4 (6), p.326-336

Limbird, Lee E

2004

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The α2A-Adrenergic Receptor Plays a Protective Role in Mouse Behavioral Models of Depression and Anxiety

The Journal of neuroscience, 2001-07, Vol.21 (13), p.4875-4882

2001

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Mutation of the α2A-Adrenoceptor Impairs Working Memory Performance and Annuls Cognitive Enhancement by Guanfacine

The Journal of neuroscience, 2002-10, Vol.22 (19), p.8771-8777

2002

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Synergies at the synapse

British journal of pharmacology, 2003-04, Vol.138 (8), p.1387-1388

LIMBIRD, Lee E

2003

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Epitope-tagged Receptor Knock-in Mice Reveal That Differential Desensitization of α2-Adrenergic Responses Is because of Ligand-selective Internalization

The Journal of biological chemistry, 2009-05, Vol.284 (19), p.13233-13243

2009

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Substitution of a Mutant α2a-Adrenergic Receptor via "Hit and Run" Gene Targeting Reveals the Role of this Subtype in Sedative, Analgesic, and Anesthetic-Sparing Responses in vivo

Proceedings of the National Academy of Sciences - PNAS, 1997-09, Vol.94 (18), p.9950-9955

1997

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Study of GPCR-protein interactions using gel overlay assays and glutathione-S-transferase-fusion protein pull-downs

Methods in molecular biology (Clifton, N.J.), 2011, Vol.746, p.347

2011

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Centralized oversight of physician-scientist faculty development at Vanderbilt: early outcomes

Academic medicine, 2008-10, Vol.83 (10), p.969-975

2008

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Knockout of spinophilin, an endogenous antagonist of arrestin-dependent α2-adrenoceptor functions, enhances receptor-mediated antinociception yet does not eliminate sex-related differences

Behavioural brain research, 2009-02, Vol.197 (2), p.457-461

2009

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5-Hydroxytryptamine Stimulates Phosphorylation of p44/p42 Mitogen-Activated Protein Kinase Activation in Bovine Aortic Endothelial Cell Cultures

Journal of cardiovascular pharmacology, 2000-03, Vol.35 (3), p.398-402

2000

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Localization of G-protein-coupled receptors in health and disease

Trends in Pharmacological Sciences, 2000-08, Vol.21 (8), p.304-308

2000

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The Three α2-Adrenergic Receptor Subtypes Achieve Basolateral Localization in Madin-Darby Canine Kidney II Cells via Different Targeting Mechanisms

The Journal of biological chemistry, 1996-03, Vol.271 (9), p.5017-5024

1996

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Calmodulin interacts with the V2 vasopressin receptor: elimination of binding to the C terminus also eliminates arginine vasopressin-stimulated elevation of intracellular calcium

The Journal of biological chemistry, 2004-11, Vol.279 (45), p.46969-46980

2004

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Heterozygous α2A-Adrenergic Receptor Mice Unveil Unique Therapeutic Benefits of Partial Agonists

Proceedings of the National Academy of Sciences - PNAS, 2002-09, Vol.99 (19), p.12471-12476

2002

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Historical Perspective for Understanding of Adrenergic Receptors

Current Topics in Membranes, 2011, Vol.67, p.1-17

Limbird, Lee E.

2011

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Pushing Forward the Future Tense: Perspectives of a Scientist

Estradiol-mediated ERK phosphorylation and apoptosis in vascular smooth muscle cells requires GPR 30

Correlation of functional and radioligand binding characteristics of GPER ligands confirming aldosterone as a GPER agonist

GPER (GPR30): A Nongenomic Receptor (GPCR) for Steroid Hormones with Implications for Cardiovascular Disease and Cancer

G protein-coupled receptor interacting proteins: Emerging roles in localization and signal transduction

Deubiquitination of CXCR4 by USP14 Is Critical for Both CXCL12-induced CXCR4 Degradation and Chemotaxis but Not ERK Activation

Adenylyl Cyclase Isoform–Selective Regulation of Vascular Smooth Muscle Proliferation and Cytoskeletal Reorganization

Aldosterone mediates metastatic spread of renal cancer via the G protein‐coupled estrogen receptor (GPER)

Copernicus Revisited: Overturning Ptolemy's View of the GPER Universe

Appropriate Polarization following Pharmacological Rescue of V2 Vasopressin Receptors Encoded by X-linked Nephrogenic Diabetes Insipidus Alleles Involves a Conformation of the Receptor That Also Attains Mature Glycosylation

The Receptor Concept: A Continuing Evolution

The α2A-Adrenergic Receptor Plays a Protective Role in Mouse Behavioral Models of Depression and Anxiety

Mutation of the α2A-Adrenoceptor Impairs Working Memory Performance and Annuls Cognitive Enhancement by Guanfacine

Synergies at the synapse

Epitope-tagged Receptor Knock-in Mice Reveal That Differential Desensitization of α2-Adrenergic Responses Is because of Ligand-selective Internalization

Substitution of a Mutant α2a-Adrenergic Receptor via "Hit and Run" Gene Targeting Reveals the Role of this Subtype in Sedative, Analgesic, and Anesthetic-Sparing Responses in vivo

Study of GPCR-protein interactions using gel overlay assays and glutathione-S-transferase-fusion protein pull-downs

Centralized oversight of physician-scientist faculty development at Vanderbilt: early outcomes

Knockout of spinophilin, an endogenous antagonist of arrestin-dependent α2-adrenoceptor functions, enhances receptor-mediated antinociception yet does not eliminate sex-related differences

5-Hydroxytryptamine Stimulates Phosphorylation of p44/p42 Mitogen-Activated Protein Kinase Activation in Bovine Aortic Endothelial Cell Cultures

Localization of G-protein-coupled receptors in health and disease

The Three α2-Adrenergic Receptor Subtypes Achieve Basolateral Localization in Madin-Darby Canine Kidney II Cells via Different Targeting Mechanisms

Calmodulin interacts with the V2 vasopressin receptor: elimination of binding to the C terminus also eliminates arginine vasopressin-stimulated elevation of intracellular calcium

Heterozygous α2A-Adrenergic Receptor Mice Unveil Unique Therapeutic Benefits of Partial Agonists

Historical Perspective for Understanding of Adrenergic Receptors

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