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Bromodomains: a new target class for drug development
Nature reviews. Drug discovery, 2019-08, Vol.18 (8), p.609
2019
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Nucleoside diphosphate kinase Nm23-H1 regulates chromosomal stability by activating the GTPase dynamin during cytokinesis
Proceedings of the National Academy of Sciences - PNAS, 2010-08, Vol.107 (35), p.15461-15466
2010
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Small molecule targeting of chromatin writers in cancer
Nature chemical biology, 2022-02, Vol.18 (2), p.124
2022
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High-throughput screens in diploid cells identify factors that contribute to the acquisition of chromosomal instability
Proceedings of the National Academy of Sciences - PNAS, 2010-08, Vol.107 (35), p.15455-15460
2010
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Regulatory T Cell Modulation by CBP/EP300 Bromodomain Inhibition
The Journal of biological chemistry, 2016-06, Vol.291 (25), p.13014-13027
2016
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Akt interacts directly with Smad3 to regulate the sensitivity to TGF-β-induced apoptosis
Nature cell biology, 2004-04, Vol.6 (4), p.366-372
2004
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Correction: Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma
eLife, 2016-07, Vol.5
2016
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Abstract A18: Targeting epigenetic dysregulation in bladder cancer through inhibition of EZH2
Clinical cancer research, 2020-08, Vol.26 (15_Supplement), p.A18-A18
2020
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Abstract 2126: Therapeutic potential of CPI-0209
Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.2126-2126
2021
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Abstract 4351: Single-cell RNA sequencing reveals transcriptomic heterogeneity in response to epigenetic inhibitors
Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.4351-4351
2019
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Abstract 4722: Efficacy of a novel EP300/CBP histone acetyltransferase inhibitor in hormone responsive breast cancer
Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.4722-4722
2019
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Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637)
ACS medicinal chemistry letters, 2016-05, Vol.7 (5), p.531-536
2016
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Abstract 4749: Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma
Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4749-4749
2016
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Abstract 4749: Bromodomain inhibition of the transcriptional coactivators CBPEP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma
Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4749-4749
2016
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Abstract B19: Targeting dependencies within apoptotic pathways through inhibition of BET bromodomains
Clinical cancer research, 2017-01, Vol.23 (1_Supplement), p.B19-B19
2017
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Abstract PR02: Targeting altered SWI/SNF function through synthetic lethal RNAi screening
Molecular cancer therapeutics, 2013-05, Vol.12 (5_Supplement), p.PR02-PR02
2013
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Abstract A20: A leukemic model of acquired resistance to BET inhibition reveals a role for CBP/EP300 bromodomains in the regulation of c-MYC expression
Molecular cancer research, 2015-10, Vol.13 (10_Supplement), p.A20-A20
2015
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Akt interacts directly with Smad3 to regulate the sensitivity to TGF-[beta]-induced apoptosis
Nature cell biology, 2004-04, Vol.6 (4), p.366
2004
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