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Mislocalisation of Activated Receptor Tyrosine Kinases – Challenges for Cancer Therapy

Trends in molecular medicine, 2020-09, Vol.26 (9), p.833-847

2020

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Regulation of protein tyrosine phosphatases by reversible oxidation

Journal of biochemistry (Tokyo), 2011-10, Vol.150 (4), p.345-356

2011

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High REDOX RESPONSIVE TRANSCRIPTION FACTOR1 Levels Result in Accumulation of Reactive Oxygen Species in Arabidopsis thaliana Shoots and Roots

Molecular plant, 2015-08, Vol.8 (8), p.1253-1273

2015

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Mislocalized Activation of Oncogenic RTKs Switches Downstream Signaling Outcomes

Molecular cell, 2009-10, Vol.36 (2), p.326-339

2009

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Lack of CD45 in FLT3-ITD mice results in a myeloproliferative phenotype, cortical porosity, and ectopic bone formation

Oncogene, 2019-06, Vol.38 (24), p.4773-4787

2019

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Modulation of FLT3 signal transduction through cytoplasmic cysteine residues indicates the potential for redox regulation

Redox biology, 2020-01, Vol.28, p.101325-101325, Article 101325

2020

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Protein tyrosine phosphatases: regulatory mechanisms

The FEBS journal, 2008-03, Vol.275 (5), p.831-847

2008

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Tyrosine Phosphorylation Regulates Maturation of Receptor Tyrosine Kinases

Molecular and Cellular Biology, 2005-05, Vol.25 (9), p.3690-3703

2005

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In Situ Proximity Ligation Assay (In Situ PLA) to Assess PTP-Protein Interactions

Methods in molecular biology (Clifton, N.J.), 2016-01, Vol.1447, p.217

2016

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Oxidation sensitivity of the catalytic cysteine of the protein-tyrosine phosphatases SHP-1 and SHP-2

Free radical biology & medicine, 2007-07, Vol.43 (1), p.100-110

2007

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Combined Activity of the Redox-Modulating Compound Setanaxib (GKT137831) with Cytotoxic Agents in the Killing of Acute Myeloid Leukemia Cells

Antioxidants, 2022-03, Vol.11 (3), p.513

2022

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Effective Dephosphorylation of Src Substrates by SHP-1

The Journal of biological chemistry, 2004-03, Vol.279 (12), p.11375-11383

2004

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The structure of the 5'-end of the protein-tyrosine phosphatase PTPRJ mRNA reveals a novel mechanism for translation attenuation

Nucleic acids research, 2008-08, Vol.36 (13), p.4443-4453

2008

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Cellular Inhibition of Protein Tyrosine Phosphatase 1B by Uncharged Thioxothiazolidinone Derivatives

Chembiochem : a European journal of chemical biology, 2007-01, Vol.8 (2), p.179-186

2007

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Inhibition of FLT3 and PDGFR tyrosine kinase activity by bis(benzo[ b]furan-2-yl)methanones

Bioorganic & medicinal chemistry, 2007-03, Vol.15 (5), p.2187-2197

2007

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Identification of Src Phosphorylation Sites in the Catenin p120

The Journal of biological chemistry, 2001-07, Vol.276 (30), p.28006-28013

2001

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Calpain-mediated degradation of reversibly oxidized protein-tyrosine phosphatase 1B

The FEBS journal, 2009-10, Vol.276 (19), p.5622-5633

2009

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UVA inactivates protein tyrosine phosphatases by calpain-mediated degradation

EMBO reports, 2004-08, Vol.5 (8), p.812-817

2004

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Binding of Phosphatidic Acid to the Protein-Tyrosine Phosphatase SHP-1 as a Basis for Activity Modulation

Biochemistry (Easton), 1999-09, Vol.38 (37), p.11993-12002

1999

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The protein-tyrosine phosphatase DEP-1 modulates growth factor-stimulated cell migration and cell-matrix adhesion

Oncogene, 2003-07, Vol.22 (27), p.4175-4185

2003

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Identification of Protein Tyrosine Phosphatases Associating with the PDGF Receptor

Biochemistry (Easton), 2003-03, Vol.42 (9), p.2691-2699

2003

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Site-Selective Regulation of Platelet-Derived Growth Factor β Receptor Tyrosine Phosphorylation by T-Cell Protein Tyrosine Phosphatase

Molecular and Cellular Biology, 2004-03, Vol.24 (5), p.2190-2201

2004

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A Single Amino Acid Exchange Inverts Susceptibility of Related Receptor Tyrosine Kinases for the ATP Site Inhibitor STI-571

The Journal of biological chemistry, 2003-02, Vol.278 (7), p.5148-5155

2003

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Phosphotyrosine 1173 Mediates Binding of the Protein-tyrosine Phosphatase SHP-1 to the Epidermal Growth Factor Receptor and Attenuation of Receptor Signaling

The Journal of biological chemistry, 1998-09, Vol.273 (38), p.24839-24846

1998

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Tricyclic quinoxalines as potent kinase inhibitors of PDGFR kinase, Flt3 and Kit

Bioorganic & medicinal chemistry, 2003-05, Vol.11 (9), p.2007-2018

2003

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Mislocalisation of Activated Receptor Tyrosine Kinases – Challenges for Cancer Therapy

Regulation of protein tyrosine phosphatases by reversible oxidation

High REDOX RESPONSIVE TRANSCRIPTION FACTOR1 Levels Result in Accumulation of Reactive Oxygen Species in Arabidopsis thaliana Shoots and Roots

Mislocalized Activation of Oncogenic RTKs Switches Downstream Signaling Outcomes

Lack of CD45 in FLT3-ITD mice results in a myeloproliferative phenotype, cortical porosity, and ectopic bone formation

Modulation of FLT3 signal transduction through cytoplasmic cysteine residues indicates the potential for redox regulation

Protein tyrosine phosphatases: regulatory mechanisms

Tyrosine Phosphorylation Regulates Maturation of Receptor Tyrosine Kinases

In Situ Proximity Ligation Assay (In Situ PLA) to Assess PTP-Protein Interactions

Oxidation sensitivity of the catalytic cysteine of the protein-tyrosine phosphatases SHP-1 and SHP-2

Combined Activity of the Redox-Modulating Compound Setanaxib (GKT137831) with Cytotoxic Agents in the Killing of Acute Myeloid Leukemia Cells

Effective Dephosphorylation of Src Substrates by SHP-1

The structure of the 5'-end of the protein-tyrosine phosphatase PTPRJ mRNA reveals a novel mechanism for translation attenuation

Cellular Inhibition of Protein Tyrosine Phosphatase 1B by Uncharged Thioxothiazolidinone Derivatives

Inhibition of FLT3 and PDGFR tyrosine kinase activity by bis(benzo[ b]furan-2-yl)methanones

Identification of Src Phosphorylation Sites in the Catenin p120

Calpain-mediated degradation of reversibly oxidized protein-tyrosine phosphatase 1B

UVA inactivates protein tyrosine phosphatases by calpain-mediated degradation

Binding of Phosphatidic Acid to the Protein-Tyrosine Phosphatase SHP-1 as a Basis for Activity Modulation

The protein-tyrosine phosphatase DEP-1 modulates growth factor-stimulated cell migration and cell-matrix adhesion

Identification of Protein Tyrosine Phosphatases Associating with the PDGF Receptor

Site-Selective Regulation of Platelet-Derived Growth Factor β Receptor Tyrosine Phosphorylation by T-Cell Protein Tyrosine Phosphatase

A Single Amino Acid Exchange Inverts Susceptibility of Related Receptor Tyrosine Kinases for the ATP Site Inhibitor STI-571

Phosphotyrosine 1173 Mediates Binding of the Protein-tyrosine Phosphatase SHP-1 to the Epidermal Growth Factor Receptor and Attenuation of Receptor Signaling

Tricyclic quinoxalines as potent kinase inhibitors of PDGFR kinase, Flt3 and Kit

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