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How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

Trends in cell biology, 2008-04, Vol.18 (4), p.157-164

2008

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GM-CSF Controls Nonlymphoid Tissue Dendritic Cell Homeostasis but Is Dispensable for the Differentiation of Inflammatory Dendritic Cells

Immunity (Cambridge, Mass.), 2012-06, Vol.36 (6), p.1031-1046

2012

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Mitochondrial Division Is Requisite to RAS-Induced Transformation and Targeted by Oncogenic MAPK Pathway Inhibitors

Molecular cell, 2015-02, Vol.57 (3), p.521-536

2015

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Sphingolipid Metabolism Cooperates with BAK and BAX to Promote the Mitochondrial Pathway of Apoptosis

Cell, 2012-03, Vol.148 (5), p.988-1000

2012

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Mitochondrial Shape Governs BAX-Induced Membrane Permeabilization and Apoptosis

Molecular cell, 2015-01, Vol.57 (1), p.69-82

2015

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Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool

Cell, 2019-08, Vol.178 (5), p.1102-1114.e17

2019

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Pin1-Induced Proline Isomerization in Cytosolic p53 Mediates BAX Activation and Apoptosis

Molecular cell, 2015-08, Vol.59 (4), p.677-684

2015

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Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization

Developmental cell, 2008-02, Vol.14 (2), p.193-204

2008

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Disruption of mitochondrial electron transport chain function potentiates the pro-apoptotic effects of MAPK inhibition

The Journal of biological chemistry, 2017-07, Vol.292 (28), p.11727-11739

2017

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BH3 Domains of BH3-Only Proteins Differentially Regulate Bax-Mediated Mitochondrial Membrane Permeabilization Both Directly and Indirectly

Molecular cell, 2005-02, Vol.17 (4), p.525-535

2005

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Direct Activation of Bax by p53 Mediates Mitochondrial Membrane Permeabilization and Apoptosis

Science (American Association for the Advancement of Science), 2004-02, Vol.303 (5660), p.1010-1014

2004

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How do I kill thee? Let me count the ways: p53 regulates PARP-1 dependent necrosis

BioEssays, 2014-01, Vol.36 (1), p.46-51

2014

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PUMA Couples the Nuclear and Cytoplasmic Proapoptotic Function of p53

Science (American Association for the Advancement of Science), 2005-09, Vol.309 (5741), p.1732-1735

2005

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A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma

Nature communications, 2022-10, Vol.13 (1), p.6041-17, Article 6041

2022

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Inducible Nitric Oxide Synthase Drives mTOR Pathway Activation and Proliferation of Human Melanoma by Reversible Nitrosylation of TSC2

Cancer research (Chicago, Ill.), 2014-02, Vol.74 (4), p.1067-1078

2014

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PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis

Nature chemical biology, 2013-03, Vol.9 (3), p.163-168

2013

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BAK activation is necessary and sufficient to drive ceramide synthase-dependent ceramide accumulation following inhibition of BCL2-like proteins

Biochemical journal, 2013-05, Vol.452 (1), p.111-119

2013

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Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins

Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (51), p.20327-20332

2008

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PUMA cooperates with direct activator proteins to promote mitochondrial outer membrane permeabilization and apoptosis

Cell cycle (Georgetown, Tex.), 2009-09, Vol.8 (17), p.2692-2696

2009

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PB1-F2 proteins from H5N1 and 20 century pandemic influenza viruses cause immunopathology

PLoS pathogens, 2010-07, Vol.6 (7), p.e1001014-e1001014

2010

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B Cell Lymphoma-2 (BCL-2) Homology Domain 3 (BH3) Mimetics Demonstrate Differential Activities Dependent upon the Functional Repertoire of Pro- and Anti-apoptotic BCL-2 Family Proteins

The Journal of biological chemistry, 2014-09, Vol.289 (38), p.26481-26491

2014

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Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription

Cancer cell, 2003-11, Vol.4 (5), p.371-381

2003

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Author Correction: A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma

Nature communications, 2023-04, Vol.14 (1), p.1923-1923, Article 1923

2023

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Mitochondrial outer membrane proteins assist Bid in Bax-mediated lipidic pore formation

Molecular biology of the cell, 2009-04, Vol.20 (8), p.2276-2285

2009

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How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

GM-CSF Controls Nonlymphoid Tissue Dendritic Cell Homeostasis but Is Dispensable for the Differentiation of Inflammatory Dendritic Cells

Mitochondrial Division Is Requisite to RAS-Induced Transformation and Targeted by Oncogenic MAPK Pathway Inhibitors

Sphingolipid Metabolism Cooperates with BAK and BAX to Promote the Mitochondrial Pathway of Apoptosis

Mitochondrial Shape Governs BAX-Induced Membrane Permeabilization and Apoptosis

Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool

Pin1-Induced Proline Isomerization in Cytosolic p53 Mediates BAX Activation and Apoptosis

Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization

PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes

Disruption of mitochondrial electron transport chain function potentiates the pro-apoptotic effects of MAPK inhibition

BH3 Domains of BH3-Only Proteins Differentially Regulate Bax-Mediated Mitochondrial Membrane Permeabilization Both Directly and Indirectly

Direct Activation of Bax by p53 Mediates Mitochondrial Membrane Permeabilization and Apoptosis

How do I kill thee? Let me count the ways: p53 regulates PARP-1 dependent necrosis

PUMA Couples the Nuclear and Cytoplasmic Proapoptotic Function of p53

A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma

Inducible Nitric Oxide Synthase Drives mTOR Pathway Activation and Proliferation of Human Melanoma by Reversible Nitrosylation of TSC2

PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis

BAK activation is necessary and sufficient to drive ceramide synthase-dependent ceramide accumulation following inhibition of BCL2-like proteins

Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins

PUMA cooperates with direct activator proteins to promote mitochondrial outer membrane permeabilization and apoptosis

PB1-F2 proteins from H5N1 and 20 century pandemic influenza viruses cause immunopathology

B Cell Lymphoma-2 (BCL-2) Homology Domain 3 (BH3) Mimetics Demonstrate Differential Activities Dependent upon the Functional Repertoire of Pro- and Anti-apoptotic BCL-2 Family Proteins

Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription

Author Correction: A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma

Mitochondrial outer membrane proteins assist Bid in Bax-mediated lipidic pore formation

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