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Mitochondrial dysfunction in cancer: Potential roles of ATF5 and the mitochondrial UPR

Seminars in cancer biology, 2017-12, Vol.47, p.43-49

2017

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A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging

Science (American Association for the Advancement of Science), 2015-03, Vol.347 (6228), p.1374-1377

2015

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The mitochondrial unfolded protein response: Signaling from the powerhouse

The Journal of biological chemistry, 2017-08, Vol.292 (33), p.13500-13506

2017

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Mitochondrial Import Efficiency of ATFS-1 Regulates Mitochondrial UPR Activation

Science (American Association for the Advancement of Science), 2012-08, Vol.337 (6094), p.587-590

2012

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Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial unfolded protein response

Nature (London), 2016-05, Vol.533 (7603), p.416-419

2016

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Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection

Nature (London), 2014-12, Vol.516 (7531), p.414-417

2014

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Protective coupling of mitochondrial function and protein synthesis via the eIF2α kinase GCN-2

PLoS genetics, 2012-06, Vol.8 (6), p.e1002760-e1002760

2012

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Cardioprotection by the mitochondrial unfolded protein response requires ATF5

American journal of physiology. Heart and circulatory physiology, 2019-08, Vol.317 (2), p.H472-H478

2019

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Mitophagy and the mitochondrial unfolded protein response in neurodegeneration and bacterial infection

BMC biology, 2015-04, Vol.13 (1), p.22-22, Article 22

2015

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UPR mt regulation and output: a stress response mediated by mitochondrial-nuclear communication

Cell research, 2018-03, Vol.28 (3), p.281

2018

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UPRmt scales mitochondrial network expansion with protein synthesis via mitochondrial import in Caenorhabditis elegans

Nature communications, 2021-01, Vol.12 (1), p.479-479, Article 479

2021

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The nuclear hormone receptor NHR-86 controls anti-pathogen responses in C. elegans

PLoS genetics, 2019-01, Vol.15 (1), p.e1007935-e1007935

2019

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Genome-wide detection of CRISPR editing in vivo using GUIDE-tag

Nature communications, 2022-01, Vol.13 (1), p.437-437, Article 437

2022

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Ubiquitin-like protein 5 positively regulates chaperone gene expression in the mitochondrial unfolded protein response

Genetics (Austin), 2006-09, Vol.174 (1), p.229-239

2006

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Mitochondrial dysfunction, aging, and the mitochondrial unfolded protein response in Caenorhabditis elegans

Genetics (Austin), 2022-11, Vol.222 (4)

2022

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Mitochondrial and nuclear accumulation of the transcription factor ATFS-1 promotes OXPHOS recovery during the UPR(mt)

Molecular cell, 2015-04, Vol.58 (1), p.123-133

2015

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Metabolism and the UPR(mt)

Molecular cell, 2016-03, Vol.61 (5), p.677-682

2016

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UPR(mt)-mediated cytoprotection and organismal aging

Biochimica et biophysica acta, 2015-11, Vol.1847 (11), p.1448

2015

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Proteasomal adaptation to environmental stress links resistance to proteotoxicity with longevity in Caenorhabditis elegans

Proceedings of the National Academy of Sciences - PNAS, 2008-05, Vol.105 (19), p.7094-7099

2008

Volltextzugriff (PDF)

Mitochondrial protein quality control during biogenesis and aging

Trends in biochemical sciences (Amsterdam. Regular ed.), 2011-05, Vol.36 (5), p.254-261

2011

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Integrating the UPRmt into the mitochondrial maintenance network

Critical reviews in biochemistry and molecular biology, 2017-06, Vol.52 (3), p.304-313

2017

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Histone deacetylases 1 and 2 silence cryptic transcription to promote mitochondrial function during cardiogenesis

Science advances, 2020-04, Vol.6 (15), p.eaax5150-eaax5150

2020

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Cell biology: Surviving import failure

Nature (London), 2015-08, Vol.524 (7566), p.419-420

Haynes, Cole M

2015

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Mitochondrial UPR repression during Pseudomonas aeruginosa infection requires the bZIP protein ZIP-3

Proceedings of the National Academy of Sciences - PNAS, 2019-03, Vol.116 (13), p.6146-6151

2019

Volltextzugriff (PDF)

Thioredoxin-related Protein 32 Is an Arsenite-regulated Thiol Reductase of the Proteasome 19 S Particle

The Journal of biological chemistry, 2009-05, Vol.284 (22), p.15233-15245

2009

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Mitochondrial dysfunction in cancer: Potential roles of ATF5 and the mitochondrial UPR

A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging

The mitochondrial unfolded protein response: Signaling from the powerhouse

Mitochondrial Import Efficiency of ATFS-1 Regulates Mitochondrial UPR Activation

Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial unfolded protein response

Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection

Protective coupling of mitochondrial function and protein synthesis via the eIF2α kinase GCN-2

Cardioprotection by the mitochondrial unfolded protein response requires ATF5

Mitophagy and the mitochondrial unfolded protein response in neurodegeneration and bacterial infection

UPR mt regulation and output: a stress response mediated by mitochondrial-nuclear communication

UPRmt scales mitochondrial network expansion with protein synthesis via mitochondrial import in Caenorhabditis elegans

The nuclear hormone receptor NHR-86 controls anti-pathogen responses in C. elegans

Genome-wide detection of CRISPR editing in vivo using GUIDE-tag

Ubiquitin-like protein 5 positively regulates chaperone gene expression in the mitochondrial unfolded protein response

Mitochondrial dysfunction, aging, and the mitochondrial unfolded protein response in Caenorhabditis elegans

Mitochondrial and nuclear accumulation of the transcription factor ATFS-1 promotes OXPHOS recovery during the UPR(mt)

Metabolism and the UPR(mt)

UPR(mt)-mediated cytoprotection and organismal aging

Proteasomal adaptation to environmental stress links resistance to proteotoxicity with longevity in Caenorhabditis elegans

Mitochondrial protein quality control during biogenesis and aging

Integrating the UPRmt into the mitochondrial maintenance network

Histone deacetylases 1 and 2 silence cryptic transcription to promote mitochondrial function during cardiogenesis

Cell biology: Surviving import failure

Mitochondrial UPR repression during Pseudomonas aeruginosa infection requires the bZIP protein ZIP-3

Thioredoxin-related Protein 32 Is an Arsenite-regulated Thiol Reductase of the Proteasome 19 S Particle

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