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The Senescence-Associated Secretory Phenotype: Critical Effector in Skin Cancer and Aging

Journal of investigative dermatology, 2016-11, Vol.136 (11), p.2133-2139

2016

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Cytoplasmic chromatin triggers inflammation in senescence and cancer

Nature (London), 2017-10, Vol.550 (7676), p.402-406

2017

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The Unexpected Noncatalytic Roles of Histone Modifiers in Development and Disease

Trends in genetics, 2019-09, Vol.35 (9), p.645-657

2019

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Molecular Mechanisms of Cutaneous Squamous Cell Carcinoma

International journal of molecular sciences, 2022-03, Vol.23 (7), p.3478

2022

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Histone modifiers: Dynamic regulators of the cutaneous transcriptome

Journal of dermatological science, 2018-03, Vol.89 (3), p.226-232

2018

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lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and normal cells

Proceedings of the National Academy of Sciences - PNAS, 2007-03, Vol.104 (12), p.4949-4954

2007

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CDKN2B Loss Promotes Progression from Benign Melanocytic Nevus to Melanoma

Cancer discovery, 2015-10, Vol.5 (10), p.1072-1085

2015

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Loss of TET2 Tips the Scales Toward Tumorigenesis

Journal of investigative dermatology, 2022-05, Vol.142 (5), p.1253-1255

Capell, Brian C.

2022

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Mechanisms of Cardiovascular Disease in Accelerated Aging Syndromes

Circulation research, 2007-07, Vol.101 (1), p.13-26

2007

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From Enhancers to Keratinocyte Cancers

Journal of investigative dermatology, 2021-05, Vol.141 (5), p.1134-1136

Capell, Brian C

2021

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farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model

Proceedings of the National Academy of Sciences - PNAS, 2008-10, Vol.105 (41), p.15902-15907

2008

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Inhibiting Farnesylation of Progerin Prevents the Characteristic Nuclear Blebbing of Hutchinson-Gilford Progeria Syndrome

Proceedings of the National Academy of Sciences - PNAS, 2005-09, Vol.102 (36), p.12879-12884

2005

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Progressive Vascular Smooth Muscle Cell Defects in a Mouse Model of Hutchinson-Gilford Progeria Syndrome

Proceedings of the National Academy of Sciences - PNAS, 2006-02, Vol.103 (9), p.3250-3255

2006

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Paget’s Diseases: United by Epidermis and Epigenetics

Journal of investigative dermatology, 2019-04, Vol.139 (4), p.753-754

Capell, Brian C.

2019

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Targeting SERCA2 in organotypic epidermis reveals MEK inhibition as a therapeutic strategy for Darier disease

JCI insight, 2023-09, Vol.8 (18)

2023

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Epigenetic and metabolic interplay in cutaneous squamous cell carcinoma

Experimental dermatology, 2021-08, Vol.30 (8), p.1115-1125

2021

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Protein farnesylation inhibitors cause donut-shaped cell nuclei attributable to a centrosome separation defect

Proceedings of the National Academy of Sciences - PNAS, 2011-03, Vol.108 (12), p.4997-5002

2011

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Human laminopathies: nuclei gone genetically awry

Nature reviews. Genetics, 2006-12, Vol.7 (12), p.940-952

2006

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LSD1: a viable therapeutic target in cutaneous squamous cell carcinoma?

Expert opinion on therapeutic targets, 2020-07, Vol.24 (7), p.671-678

2020

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Autophagy mediates degradation of nuclear lamina

Nature (London), 2015-11, Vol.527 (7576), p.105-109

2015

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Methyltransferases in the Pathogenesis of Keratinocyte Cancers

Cancers, 2021-07, Vol.13 (14), p.3402

2021

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Loss of Methylation Modification Marks the Presence of Psoriasis

Journal of investigative dermatology, 2020-06, Vol.140 (6), p.1127-1128

2020

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Whole-Exome and Transcriptome Analysis of UV-Exposed Epidermis and Carcinoma In Situ Reveals Early Drivers of Carcinogenesis

Journal of investigative dermatology, 2021-02, Vol.141 (2), p.295-307.e13

2021

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FBXW7 triggers degradation of KMT2D to favor growth of diffuse large B-cell lymphoma cells

Cancer research (Chicago, Ill.), 2020-06, Vol.80 (12), p.2498-2511

2020

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MLL4 mediates differentiation and tumor suppression through ferroptosis

Science advances, 2021-12, Vol.7 (50), p.eabj9141-eabj9141

2021

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The Senescence-Associated Secretory Phenotype: Critical Effector in Skin Cancer and Aging

Cytoplasmic chromatin triggers inflammation in senescence and cancer

The Unexpected Noncatalytic Roles of Histone Modifiers in Development and Disease

Molecular Mechanisms of Cutaneous Squamous Cell Carcinoma

Histone modifiers: Dynamic regulators of the cutaneous transcriptome

lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and normal cells

CDKN2B Loss Promotes Progression from Benign Melanocytic Nevus to Melanoma

Loss of TET2 Tips the Scales Toward Tumorigenesis

Mechanisms of Cardiovascular Disease in Accelerated Aging Syndromes

From Enhancers to Keratinocyte Cancers

farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model

Inhibiting Farnesylation of Progerin Prevents the Characteristic Nuclear Blebbing of Hutchinson-Gilford Progeria Syndrome

Progressive Vascular Smooth Muscle Cell Defects in a Mouse Model of Hutchinson-Gilford Progeria Syndrome

Paget’s Diseases: United by Epidermis and Epigenetics

Targeting SERCA2 in organotypic epidermis reveals MEK inhibition as a therapeutic strategy for Darier disease

Epigenetic and metabolic interplay in cutaneous squamous cell carcinoma

Protein farnesylation inhibitors cause donut-shaped cell nuclei attributable to a centrosome separation defect

Human laminopathies: nuclei gone genetically awry

LSD1: a viable therapeutic target in cutaneous squamous cell carcinoma?

Autophagy mediates degradation of nuclear lamina

Methyltransferases in the Pathogenesis of Keratinocyte Cancers

Loss of Methylation Modification Marks the Presence of Psoriasis

Whole-Exome and Transcriptome Analysis of UV-Exposed Epidermis and Carcinoma In Situ Reveals Early Drivers of Carcinogenesis

FBXW7 triggers degradation of KMT2D to favor growth of diffuse large B-cell lymphoma cells

MLL4 mediates differentiation and tumor suppression through ferroptosis

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