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Regulated methionine oxidation by monooxygenases

Free radical biology & medicine, 2017-08, Vol.109, p.141-155

2017

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Histone methylation status of H3K4me3 and H3K9me3 under methionine restriction is unstable in methionine-addicted cancer cells, but stable in normal cells

Biochemical and biophysical research communications, 2020-12, Vol.533 (4), p.1034-1038

2020

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Tumor methionine metabolism drives T-cell exhaustion in hepatocellular carcinoma

Nature communications, 2021-03, Vol.12 (1), p.1455-15, Article 1455

2021

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Extent and Instability of Trimethylation of Histone H3 Lysine Increases With Degree of Malignancy and Methionine Addiction

Cancer genomics & proteomics, 2022-01, Vol.19 (1), p.12-18

2022

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Dietary methionine influences therapy in mouse cancer models and alters human metabolism

Nature (London), 2019-08, Vol.572 (7769), p.397-401

2019

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Functional characterization of methionine sulfoxide reductases from Leptospira interrogans

Biochimica et biophysica acta. Proteins and proteomics, 2021-02, Vol.1869 (2), p.140575, Article 140575

2021

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Targeting the methionine-methionine adenosyl transferase 2A- S -adenosyl methionine axis for cancer therapy

Current opinion in oncology, 2022-09, Vol.34 (5), p.546-551

2022

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The biological significance of methionine sulfoxide stereochemistry

Free radical biology & medicine, 2011-01, Vol.50 (2), p.221-227

2011

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Methionine in proteins: The Cinderella of the proteinogenic amino acids

Protein science, 2019-10, Vol.28 (10), p.1785-1796

Aledo, Juan C.

2019

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Methionine sulfoxide and the methionine sulfoxide reductase system as modulators of signal transduction pathways: a review

Amino acids, 2021-07, Vol.53 (7), p.1011-1020

2021

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Methionine adenosyltransferase2A inhibition restores metabolism to improve regenerative capacity and strength of aged skeletal muscle

Nature communications, 2023-02, Vol.14 (1), p.886-886, Article 886

2023

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Enzyme-mediated depletion of serum L-Met abrogates prostate cancer growth via multiple mechanisms without evidence of systemic toxicity

Proceedings of the National Academy of Sciences - PNAS, 2020-06, Vol.117 (23), p.13000-13011

2020

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Downregulation of Methionine Cycle Genes MAT1A and GNMT Enriches Protein-Associated Translation Process and Worsens Hepatocellular Carcinoma Prognosis

International journal of molecular sciences, 2022-01, Vol.23 (1), p.481

2022

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Stereospecific micellar electrokinetic chromatography assay of methionine sulfoxide reductase activity employing a multiple layer coated capillary

Electrophoresis, 2013-09, Vol.34 (18), p.2712-2717

2013

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Exploiting methionine restriction for cancer treatment

Biochemical pharmacology, 2018-08, Vol.154, p.170-173

2018

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Development of ROS‐responsive amino acid‐based poly(ester amide) nanoparticle for anticancer drug delivery

Journal of biomedical materials research. Part A, 2021-04, Vol.109 (4), p.524-537

2021

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High-throughput and simultaneous quantitative analysis of homocysteine–methionine cycle metabolites and co-factors in blood plasma and cerebrospinal fluid by isotope dilution LC–MS/MS

Analytical and bioanalytical chemistry, 2017-01, Vol.409 (1), p.295-305

2017

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Metabolic Consequences of Supplemented Methionine in a Clinical Context

The Journal of nutrition, 2020-10, Vol.150 (Suppl 1), p.2538S-2547S

2020

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S-adenosylmethionine biosynthesis is a targetable metabolic vulnerability of cancer stem cells

Breast cancer research and treatment, 2019-05, Vol.175 (1), p.39-50

2019

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Cysteine and methionine oxidation in thrombotic disorders

Current opinion in chemical biology, 2023-10, Vol.76, p.102350-102350, Article 102350

2023

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The Methionine-aromatic Motif Plays a Unique Role in Stabilizing Protein Structure

The Journal of biological chemistry, 2012-10, Vol.287 (42), p.34979-34991

2012

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Mutations in MARS identified in a specific type of pulmonary alveolar proteinosis alter methionyl‐tRNA synthetase activity

The FEBS journal, 2018-07, Vol.285 (14), p.2654-2661

2018

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Drosophila methionine sulfoxide reductase A (MSRA) lacks methionine oxidase activity

Free radical biology & medicine, 2019-02, Vol.131, p.154-161

2019

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Metabolism of Sulfur-Containing Amino Acids: How the Body Copes with Excess Methionine, Cysteine, and Sulfide

The Journal of nutrition, 2020-10, Vol.150 (Suppl 1), p.2494S-2505S

Stipanuk, Martha H

2020

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Human Mat2A Uses an Ordered Kinetic Mechanism and Is Stabilized but Not Regulated by Mat2B

Biochemistry (Easton), 2021-11, Vol.60 (47), p.3621-3632

2021

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Regulated methionine oxidation by monooxygenases

Histone methylation status of H3K4me3 and H3K9me3 under methionine restriction is unstable in methionine-addicted cancer cells, but stable in normal cells

Tumor methionine metabolism drives T-cell exhaustion in hepatocellular carcinoma

Extent and Instability of Trimethylation of Histone H3 Lysine Increases With Degree of Malignancy and Methionine Addiction

Dietary methionine influences therapy in mouse cancer models and alters human metabolism

Functional characterization of methionine sulfoxide reductases from Leptospira interrogans

Targeting the methionine-methionine adenosyl transferase 2A- S -adenosyl methionine axis for cancer therapy

The biological significance of methionine sulfoxide stereochemistry

Methionine in proteins: The Cinderella of the proteinogenic amino acids

Methionine sulfoxide and the methionine sulfoxide reductase system as modulators of signal transduction pathways: a review

Methionine adenosyltransferase2A inhibition restores metabolism to improve regenerative capacity and strength of aged skeletal muscle

Enzyme-mediated depletion of serum L-Met abrogates prostate cancer growth via multiple mechanisms without evidence of systemic toxicity

Downregulation of Methionine Cycle Genes MAT1A and GNMT Enriches Protein-Associated Translation Process and Worsens Hepatocellular Carcinoma Prognosis

Stereospecific micellar electrokinetic chromatography assay of methionine sulfoxide reductase activity employing a multiple layer coated capillary

Exploiting methionine restriction for cancer treatment

Development of ROS‐responsive amino acid‐based poly(ester amide) nanoparticle for anticancer drug delivery

High-throughput and simultaneous quantitative analysis of homocysteine–methionine cycle metabolites and co-factors in blood plasma and cerebrospinal fluid by isotope dilution LC–MS/MS

Metabolic Consequences of Supplemented Methionine in a Clinical Context

S-adenosylmethionine biosynthesis is a targetable metabolic vulnerability of cancer stem cells

Cysteine and methionine oxidation in thrombotic disorders

The Methionine-aromatic Motif Plays a Unique Role in Stabilizing Protein Structure

Mutations in MARS identified in a specific type of pulmonary alveolar proteinosis alter methionyl‐tRNA synthetase activity

Drosophila methionine sulfoxide reductase A (MSRA) lacks methionine oxidase activity

Metabolism of Sulfur-Containing Amino Acids: How the Body Copes with Excess Methionine, Cysteine, and Sulfide

Human Mat2A Uses an Ordered Kinetic Mechanism and Is Stabilized but Not Regulated by Mat2B

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