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Design, Synthesis, and Evaluation of Conformationally Restricted Acetanilides as Potent and Selective β3 Adrenergic Receptor Agonists for the Treatment of Overactive Bladder

Journal of medicinal chemistry, 2014-02, Vol.57 (4), p.1437-1453

2014

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A Computational Physics-based Approach to Predict Unbound Brain-to-Plasma Partition Coefficient, Kp,uu

Journal of chemical information and modeling, 2023-06, Vol.63 (12), p.3786-3798

2023

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The urinary metabolite profile of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is predictive of colon dna adducts after a low-dose exposure in humans

Cancer research (Chicago, Ill.), 2006-11, Vol.66 (21), p.10541-10547

2006

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In Vivo Efficacy of Relebactam (MK-7655) in Combination with Imipenem-Cilastatin in Murine Infection Models

Antimicrobial agents and chemotherapy, 2018-08, Vol.62 (8)

2018

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A Computational Physics-based Approach to Predict Unbound Brain-to-Plasma Partition Coefficient, K p,uu

Journal of chemical information and modeling, 2023-06, Vol.63 (12), p.3786-3798

2023

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Accelerator Mass Spectrometry for Biomedical Research

Methods in Enzymology, 2005, Vol.402, p.423-443

2005

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Inflammation and Atrophy Precede Prostatic Neoplasia in a PhIP-Induced Rat Model

Neoplasia (New York, N.Y.), 2006-09, Vol.8 (9), p.708-715

2006

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Discovery of phenyl acetamides as potent and selective GPR119 agonists

Bioorganic & medicinal chemistry letters, 2017-03, Vol.27 (5), p.1124-1128

2017

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Discovery of benzamides as potent human β3 adrenergic receptor agonists

Bioorganic & medicinal chemistry letters, 2016-01, Vol.26 (1), p.55-59

2016

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Optimization of Preclinical Metabolism for Somatostatin Receptor Subtype 5‑Selective Antagonists

ACS medicinal chemistry letters, 2018-11, Vol.9 (11), p.1088-1093

2018

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The effects of coffee on enzymes involved in metabolism of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine in rats

Chemico-biological interactions, 2003-06, Vol.145 (3), p.251-265

2003

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Sample Preparation for Quantitation of Tritium by Accelerator Mass Spectrometry

Analytical chemistry (Washington), 2002-12, Vol.74 (24), p.6285-6290

2002

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Application of accelerated mass spectrometry (AMS) in DNA adduct quantification and identification

Toxicology letters, 1998-12, Vol.102-103 (1-3), p.435-439

1998

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DNA isolation and sample preparation for quantification of adduct levels by accelerator mass spectrometry

Methods in molecular biology (Clifton, N.J.), 2014, Vol.1105, p.147

2014

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Discovery and Optimization of a Novel Triazole Series of GPR142 Agonists for the Treatment of Type 2 Diabetes

ACS medicinal chemistry letters, 2016-12, Vol.7 (12), p.1107-1111

2016

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Metabolism of the Food-Borne Mutagen 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline in Humans

Chemical research in toxicology, 1998-03, Vol.11 (3), p.217-225

1998

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Design of Potent and Orally Active GPR119 Agonists for the Treatment of Type II Diabetes

ACS medicinal chemistry letters, 2015-08, Vol.6 (8), p.936-941

2015

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DNA and Protein Adduct Formation in the Colon and Blood of Humans after Exposure to a Dietary-relevant Dose of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

Cancer epidemiology, biomarkers & prevention, 1999-06, Vol.8 (6), p.507-512

1999

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DNA isolation and sample preparation for quantification of adduct levels by accelerator mass spectrometry

Methods in molecular biology (Clifton, N.J.), 2005, Vol.291, p.21

2005

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Use of Tritium Accelerator Mass Spectrometry for Tree Ring Analysis

Environmental science & technology, 2002-07, Vol.36 (13), p.2848-2852

2002

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Synthesis and spectroscopic characterization of site-specific 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine oligodeoxyribonucleotide adducts

Nucleic acids research, 2001-05, Vol.29 (9), p.1951-1959

Brown, K.

2001

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Attomole Detection of 3H in Biological Samples Using Accelerator Mass Spectrometry: Application in Low-Dose, Dual-Isotope Tracer Studies in Conjunction with 14C Accelerator Mass Spectrometry

Chemical research in toxicology, 1998-10, Vol.11 (10), p.1217-1222

1998

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Inflammation and Atrophy Precede Prostatic Neoplasia in a PhIP-Induced Rat Model1

Neoplasia (New York, N.Y.), 2006-09, Vol.8 (9), p.708-715

2006

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Detectable levels of serum aflatoxin B1-albumin adducts in the United Kingdom population: implications for aflatoxin-B1 exposure in the United Kingdom

Cancer epidemiology, biomarkers & prevention, 1998-05, Vol.7 (5), p.441

1998

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Design, Synthesis, and Evaluation of Conformationally Restricted Acetanilides as Potent and Selective β3 Adrenergic Receptor Agonists for the Treatment of Overactive Bladder

A Computational Physics-based Approach to Predict Unbound Brain-to-Plasma Partition Coefficient, Kp,uu

The urinary metabolite profile of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is predictive of colon dna adducts after a low-dose exposure in humans

In Vivo Efficacy of Relebactam (MK-7655) in Combination with Imipenem-Cilastatin in Murine Infection Models

A Computational Physics-based Approach to Predict Unbound Brain-to-Plasma Partition Coefficient, K p,uu

Accelerator Mass Spectrometry for Biomedical Research

Inflammation and Atrophy Precede Prostatic Neoplasia in a PhIP-Induced Rat Model

Discovery of phenyl acetamides as potent and selective GPR119 agonists

Discovery of benzamides as potent human β3 adrenergic receptor agonists

Optimization of Preclinical Metabolism for Somatostatin Receptor Subtype 5‑Selective Antagonists

The effects of coffee on enzymes involved in metabolism of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine in rats

Sample Preparation for Quantitation of Tritium by Accelerator Mass Spectrometry

Application of accelerated mass spectrometry (AMS) in DNA adduct quantification and identification

DNA isolation and sample preparation for quantification of adduct levels by accelerator mass spectrometry

Discovery and Optimization of a Novel Triazole Series of GPR142 Agonists for the Treatment of Type 2 Diabetes

Metabolism of the Food-Borne Mutagen 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline in Humans

Design of Potent and Orally Active GPR119 Agonists for the Treatment of Type II Diabetes

DNA and Protein Adduct Formation in the Colon and Blood of Humans after Exposure to a Dietary-relevant Dose of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

DNA isolation and sample preparation for quantification of adduct levels by accelerator mass spectrometry

Use of Tritium Accelerator Mass Spectrometry for Tree Ring Analysis

Synthesis and spectroscopic characterization of site-specific 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine oligodeoxyribonucleotide adducts

Design, Synthesis, and Evaluation of Conformationally Restricted Acetanilides as Potent and Selective β 3 Adrenergic Receptor Agonists for the Treatment of Overactive Bladder

Attomole Detection of 3H in Biological Samples Using Accelerator Mass Spectrometry: Application in Low-Dose, Dual-Isotope Tracer Studies in Conjunction with 14C Accelerator Mass Spectrometry

Inflammation and Atrophy Precede Prostatic Neoplasia in a PhIP-Induced Rat Model1

Detectable levels of serum aflatoxin B1-albumin adducts in the United Kingdom population: implications for aflatoxin-B1 exposure in the United Kingdom

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