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Mechanism of adrenergic CaV1.2 stimulation revealed by proximity proteomics

Nature (London), 2020-01, Vol.577 (7792), p.695-700

2020

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Structure and selectivity in bestrophin ion channels

Science (American Association for the Advancement of Science), 2014-10, Vol.346 (6207), p.355-359

2014

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Distinct RGK GTPases differentially use α1- and auxiliary β-binding-dependent mechanisms to inhibit CaV1.2/CaV2.2 channels

PloS one, 2012-05, Vol.7 (5), p.e37079-e37079

2012

Volltextzugriff (PDF)

Potassium channels in the heart: structure, function and regulation

The Journal of physiology, 2017-04, Vol.595 (7), p.2209-2228

2017

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High-fat diet-dependent modulation of the delayed rectifier K+ current in adult guinea pig atrial myocytes

Biochemical and biophysical research communications, 2016-06, Vol.474 (3), p.554-559

2016

Volltextzugriff (PDF)

Sculpting ion channel functional expression with engineered ubiquitin ligases

eLife, 2017-12, Vol.6

2017

Volltextzugriff (PDF)

BIN1 localizes the L-type calcium channel to cardiac T-tubules

PLoS biology, 2010-02, Vol.8 (2), p.e1000312-e1000312

2010

Volltextzugriff (PDF)

A potent voltage-gated calcium channel inhibitor engineered from a nanobody targeted to auxiliary CaVβ subunits

eLife, 2019-08, Vol.8

2019

Volltextzugriff (PDF)

Regulation of Blood Pressure by Targeting CaV1.2-Galectin-1 Protein Interaction

Circulation (New York, N.Y.), 2018-10, Vol.138 (14), p.1431-1445

2018

Volltextzugriff (PDF)

Selective posttranslational inhibition of CaVβ1-associated voltage-dependent calcium channels with a functionalized nanobody

Nature communications, 2022-12, Vol.13 (1), p.7556-7556, Article 7556

2022

Volltextzugriff (PDF)

Development of a High-Throughput Flow Cytometry Assay to Monitor Defective Trafficking and Rescue of Long QT2 Mutant hERG Channels

Frontiers in physiology, 2018-04, Vol.9, p.397-397

2018

Volltextzugriff (PDF)

Transfer RNA-mediated restoration of potassium current and electrical correction in premature termination long-QT syndrome hERG mutants

Molecular therapy. Nucleic acids, 2023-12, Vol.34, p.102032-102032, Article 102032

2023

Volltextzugriff (PDF)

A light-gated potassium channel for sustained neuronal inhibition

Nature methods, 2018-11, Vol.15 (11), p.969

2018

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Divergent regulation of KCNQ1/E1 by targeted recruitment of protein kinase A to distinct sites on the channel complex

eLife, 2023-08, Vol.12

2023

Volltextzugriff (PDF)

Ion channels: channel production and optical methods

2021

Volltextzugriff (PDF)

Perturbation of the host cell Ca2+ homeostasis and ER-mitochondria contact sites by the SARS-CoV-2 structural proteins E and M

Cell death & disease, 2023-04, Vol.14 (4), p.297-297, Article 297

2023

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LQT1 mutations in KCNQ1 C-terminus assembly domain suppress IKs using different mechanisms

Cardiovascular research, 2014-12, Vol.104 (3), p.501-511

2014

Volltextzugriff (PDF)

Ion channels: channel chemical biology, engineering, and physiological function

2021

Volltextzugriff (PDF)

Research Highlights: Biophysics of Calcium

Biophysical journal, 2020-10, Vol.119 (8), p.1472-1473

Colecraft, Henry M.

2020

Volltextzugriff (PDF)

Pharmacological rescue of specific long QT variants of KCNQ1/KCNE1 channels

Frontiers in physiology, 2022-11, Vol.13, p.902224-902224

2022

Volltextzugriff (PDF)

David T. Yue: In Memoriam

Neuron (Cambridge, Mass.), 2015-03, Vol.85 (6), p.1158-1161

2015

Volltextzugriff (PDF)

Manipulating L-type calcium channels in cardiomyocytes using split-intein protein transsplicing

Proceedings of the National Academy of Sciences - PNAS, 2013-09, Vol.110 (38), p.15461-15466

2013

Volltextzugriff (PDF)

Molecular Mechanisms, and Selective Pharmacological Rescue, of Rem-Inhibited CaV1.2 Channels in Heart

Circulation research, 2010-09, Vol.107 (5), p.620-630

2010

Volltextzugriff (PDF)

hERG 1a LQT2 C-terminus truncation mutants display hERG 1b-dependent dominant negative mechanisms

Heart rhythm, 2016-05, Vol.13 (5), p.1121-1130

2016

Volltextzugriff (PDF)

Correction: Inhibition of NAPDH Oxidase 2 (NOX2) Prevents Oxidative Stress and Mitochondrial Abnormalities Caused by Saturated Fat in Cardiomyocytes

PloS one, 2017-03, Vol.12 (3), p.e0174525-e0174525

2017

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Mechanism of adrenergic CaV1.2 stimulation revealed by proximity proteomics

Structure and selectivity in bestrophin ion channels

Distinct RGK GTPases differentially use α1- and auxiliary β-binding-dependent mechanisms to inhibit CaV1.2/CaV2.2 channels

Potassium channels in the heart: structure, function and regulation

High-fat diet-dependent modulation of the delayed rectifier K+ current in adult guinea pig atrial myocytes

Sculpting ion channel functional expression with engineered ubiquitin ligases

BIN1 localizes the L-type calcium channel to cardiac T-tubules

A potent voltage-gated calcium channel inhibitor engineered from a nanobody targeted to auxiliary CaVβ subunits

Regulation of Blood Pressure by Targeting CaV1.2-Galectin-1 Protein Interaction

Selective posttranslational inhibition of CaVβ1-associated voltage-dependent calcium channels with a functionalized nanobody

Development of a High-Throughput Flow Cytometry Assay to Monitor Defective Trafficking and Rescue of Long QT2 Mutant hERG Channels

Transfer RNA-mediated restoration of potassium current and electrical correction in premature termination long-QT syndrome hERG mutants

A light-gated potassium channel for sustained neuronal inhibition

Divergent regulation of KCNQ1/E1 by targeted recruitment of protein kinase A to distinct sites on the channel complex

Ion channels: channel production and optical methods

Perturbation of the host cell Ca2+ homeostasis and ER-mitochondria contact sites by the SARS-CoV-2 structural proteins E and M

LQT1 mutations in KCNQ1 C-terminus assembly domain suppress IKs using different mechanisms

Ion channels: channel chemical biology, engineering, and physiological function

Research Highlights: Biophysics of Calcium

Pharmacological rescue of specific long QT variants of KCNQ1/KCNE1 channels

David T. Yue: In Memoriam

Manipulating L-type calcium channels in cardiomyocytes using split-intein protein transsplicing

Molecular Mechanisms, and Selective Pharmacological Rescue, of Rem-Inhibited CaV1.2 Channels in Heart

hERG 1a LQT2 C-terminus truncation mutants display hERG 1b-dependent dominant negative mechanisms

Correction: Inhibition of NAPDH Oxidase 2 (NOX2) Prevents Oxidative Stress and Mitochondrial Abnormalities Caused by Saturated Fat in Cardiomyocytes

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