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Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance

Nature communications, 2017-11, Vol.8 (1), p.1865-15, Article 1865

2017

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A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology

Nature cancer, 2022-02, Vol.3 (2), p.232-250

2022

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Anterior gradient 2 is a binding stabilizer of hypoxia inducible factor‐1α that enhances CoCl2‐induced doxorubicin resistance in breast cancer cells

Cancer science, 2015-08, Vol.106 (8), p.1041-1049

2015

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Sal‐like protein 2 upregulates p16 expression through a proximal promoter element

Cancer science, 2015-03, Vol.106 (3), p.253-261

2015

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TBCRC 039: a phase II study of preoperative ruxolitinib with or without paclitaxel for triple-negative inflammatory breast cancer

Breast cancer research : BCR, 2024-01, Vol.26 (1), p.20-20, Article 20

2024

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Estrogen Receptor Alpha Mutations in Breast Cancer Cells Cause Gene Expression Changes through Constant Activity and Secondary Effects

Cancer research (Chicago, Ill.), 2021-02, Vol.81 (3), p.539-551

2021

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Upregulation of IRS1 Enhances IGF1 Response in Y537S and D538G ESR1 Mutant Breast Cancer Cells

Endocrinology (Philadelphia), 2018-01, Vol.159 (1), p.285-296

2018

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Steroid Hormone Receptor and Infiltrating Immune Cell Status Reveals Therapeutic Vulnerabilities of ESR1 -Mutant Breast Cancer

Cancer research (Chicago, Ill.), 2021-02, Vol.81 (3), p.732-746

2021

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Anterior Gradient-2 monoclonal antibody inhibits lung cancer growth and metastasis by upregulating p53 pathway and without exerting any toxicological effects: A preclinical study

Cancer letters, 2019-05, Vol.449, p.125-134

2019

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The EstroGene Database Reveals Diverse Temporal, Context-Dependent, and Bidirectional Estrogen Receptor Regulomes in Breast Cancer

Cancer research (Chicago, Ill.), 2023-08, Vol.83 (16), p.2656-2674

2023

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Combination Therapies to Improve the Efficacy of Immunotherapy in Triple-negative Breast Cancer

Molecular cancer therapeutics, 2023-11, Vol.22 (11), p.1304-1318

2023

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Induction of anterior gradient 2 (AGR2) plays a key role in insulin-like growth factor-1 (IGF-1)-induced breast cancer cell proliferation and migration

Medical oncology (Northwood, London, England), 2015-06, Vol.32 (6), p.577-577, Article 178

2015

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Clinically Observed Estrogen Receptor Alpha Mutations within the Ligand-Binding Domain Confer Distinguishable Phenotypes

Oncology, 2018-01, Vol.94 (3), p.176-189

2018

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FA-PEG decorated MOF nanoparticles as a targeted drug delivery system for controlled release of an autophagy inhibitor

Biomaterials science, 2018-09, Vol.6 (1), p.2582-259

2018

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Prostaglandin E2 confers protection against diabetic coronary atherosclerosis by stimulating M2 macrophage polarization via the activation of the CREB/BDNF/TrkB signaling pathway

The FASEB journal, 2020-06, Vol.34 (6), p.7360-7371

2020

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Recurrent vomiting caused by the migration of internal pancreatic-duct stent to straddle at the gastrointestinal anastomotic site

Asian journal of surgery, 2024-02, Vol.47 (2), p.1153-1154

2024

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The characteristic patterns of individual brain susceptibility networks underlie Alzheimer's disease and white matter hyperintensity-related cognitive impairment

Translational psychiatry, 2024-04, Vol.14 (1), p.177-13, Article 177

2024

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Judgment of benign and early malignant colorectal tumors from ultrasound images with deep multi-View fusion

Computer methods and programs in biomedicine, 2022-03, Vol.215, p.106634-106634, Article 106634

2022

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Construction and validation of a predictive model for the risk of bowel resection in adults with incarcerated groin hernia

BMC surgery, 2023-12, Vol.23 (1), p.375-375, Article 375

2023

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Knockdown of LncRNA SCAMP1 suppressed malignant biological behaviours of glioma cells via modulating miR‐499a‐5p/LMX1A/NLRC5 pathway

Journal of cellular and molecular medicine, 2019-08, Vol.23 (8), p.5048-5062

2019

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Cancer cells co-opt nociceptive nerves to thrive in nutrient-poor environments and upon nutrient-starvation therapies

Cell metabolism, 2022-12, Vol.34 (12), p.1999-2017.e10

2022

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The significance of serum Klotho to hearing loss: a potential protector under noise pollution

Environmental science and pollution research international, 2023-10, Vol.30 (47), p.104464-104476

2023

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Hypoxia promotes EV secretion by impairing lysosomal homeostasis in HNSCC through negative regulation of ATP6V1A by HIF‐1α

Journal of extracellular vesicles, 2023-02, Vol.12 (2), p.e12310-n/a

2023

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Lower cerebrovascular reactivity in prefrontal cortex and weaker negative functional connectivity between prefrontal cortex and insula contribute to white matter hyperintensity-related anxiety or depression

Journal of affective disorders, 2024-06, Vol.354, p.526-535

2024

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Comprehensive Proteogenomic Profiling Reveals the Molecular Characteristics of Colorectal Cancer at Distinct Stages of Progression

Cancer research (Chicago, Ill.), 2024-09, Vol.84 (17), p.2888-2910

2024

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Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance

A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology

Anterior gradient 2 is a binding stabilizer of hypoxia inducible factor‐1α that enhances CoCl2‐induced doxorubicin resistance in breast cancer cells

Sal‐like protein 2 upregulates p16 expression through a proximal promoter element

TBCRC 039: a phase II study of preoperative ruxolitinib with or without paclitaxel for triple-negative inflammatory breast cancer

Estrogen Receptor Alpha Mutations in Breast Cancer Cells Cause Gene Expression Changes through Constant Activity and Secondary Effects

Upregulation of IRS1 Enhances IGF1 Response in Y537S and D538G ESR1 Mutant Breast Cancer Cells

Steroid Hormone Receptor and Infiltrating Immune Cell Status Reveals Therapeutic Vulnerabilities of ESR1 -Mutant Breast Cancer

Anterior Gradient-2 monoclonal antibody inhibits lung cancer growth and metastasis by upregulating p53 pathway and without exerting any toxicological effects: A preclinical study

The EstroGene Database Reveals Diverse Temporal, Context-Dependent, and Bidirectional Estrogen Receptor Regulomes in Breast Cancer

Combination Therapies to Improve the Efficacy of Immunotherapy in Triple-negative Breast Cancer

Induction of anterior gradient 2 (AGR2) plays a key role in insulin-like growth factor-1 (IGF-1)-induced breast cancer cell proliferation and migration

Clinically Observed Estrogen Receptor Alpha Mutations within the Ligand-Binding Domain Confer Distinguishable Phenotypes

FA-PEG decorated MOF nanoparticles as a targeted drug delivery system for controlled release of an autophagy inhibitor

Prostaglandin E2 confers protection against diabetic coronary atherosclerosis by stimulating M2 macrophage polarization via the activation of the CREB/BDNF/TrkB signaling pathway

Recurrent vomiting caused by the migration of internal pancreatic-duct stent to straddle at the gastrointestinal anastomotic site

The characteristic patterns of individual brain susceptibility networks underlie Alzheimer's disease and white matter hyperintensity-related cognitive impairment

Judgment of benign and early malignant colorectal tumors from ultrasound images with deep multi-View fusion

Construction and validation of a predictive model for the risk of bowel resection in adults with incarcerated groin hernia

Knockdown of LncRNA SCAMP1 suppressed malignant biological behaviours of glioma cells via modulating miR‐499a‐5p/LMX1A/NLRC5 pathway

Cancer cells co-opt nociceptive nerves to thrive in nutrient-poor environments and upon nutrient-starvation therapies

The significance of serum Klotho to hearing loss: a potential protector under noise pollution

Hypoxia promotes EV secretion by impairing lysosomal homeostasis in HNSCC through negative regulation of ATP6V1A by HIF‐1α

Lower cerebrovascular reactivity in prefrontal cortex and weaker negative functional connectivity between prefrontal cortex and insula contribute to white matter hyperintensity-related anxiety or depression

Comprehensive Proteogenomic Profiling Reveals the Molecular Characteristics of Colorectal Cancer at Distinct Stages of Progression

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