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Thermodynamics of protein destabilization in live cells

Proceedings of the National Academy of Sciences - PNAS, 2015-10, Vol.112 (40), p.12402-12407

2015

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Interplay between Conformational Entropy and Solvation Entropy in Protein–Ligand Binding

Journal of the American Chemical Society, 2019-02, Vol.141 (5), p.2012-2026

2019

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DNA building blocks: keeping control of manufacture

Critical reviews in biochemistry and molecular biology, 2012-01, Vol.47 (1), p.50-63

2012

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The Carbohydrate-Binding Site in Galectin-3 Is Preorganized To Recognize a Sugarlike Framework of Oxygens: Ultra-High-Resolution Structures and Water Dynamics

Biochemistry (Easton), 2012-01, Vol.51 (1), p.296-306

2012

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Entropy–Entropy Compensation between the Protein, Ligand, and Solvent Degrees of Freedom Fine-Tunes Affinity in Ligand Binding to Galectin-3C

JACS Au, 2021-04, Vol.1 (4), p.484-500

2021

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DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously

Nature communications, 2021-01, Vol.12 (1), p.708-13, Article 708

2021

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The engineered CD80 variant fusion therapeutic davoceticept combines checkpoint antagonism with conditional CD28 costimulation for anti-tumor immunity

Nature communications, 2022-04, Vol.13 (1), p.1790-1790, Article 1790

2022

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Structure-Function Analysis of Heterodimer Formation, Oligomerization, and Receptor Binding of the Staphylococcus aureus Bi-component Toxin LukGH

The Journal of biological chemistry, 2015-01, Vol.290 (1), p.142-156

2015

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Nucleotide binding to the ATP-cone in anaerobic ribonucleotide reductases allosterically regulates activity by modulating substrate binding

eLife, 2024-07, Vol.12

2024

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Folding Catalysis by Transient Coordination of Zn2+ to the Cu Ligands of the ALS-Associated Enzyme Cu/Zn Superoxide Dismutase 1

Journal of the American Chemical Society, 2010-09, Vol.132 (38), p.13495-13504

2010

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A nucleotide-sensing oligomerization mechanism that controls NrdR-dependent transcription of ribonucleotide reductases

Nature communications, 2022-05, Vol.13 (1), p.2700-10, Article 2700

2022

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MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM

Proceedings of the National Academy of Sciences - PNAS, 2019-04, Vol.116 (15), p.7533-7542

2019

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Structural and Biophysical Characterization of Human EXTL3: Domain Organization, Glycosylation, and Solution Structure

Biochemistry (Easton), 2018-02, Vol.57 (7), p.1166-1177

2018

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NAD+ pool depletion as a signal for the Rex regulon involved in Streptococcus agalactiae virulence

PLoS pathogens, 2021-08, Vol.17 (8), p.e1009791-e1009791

2021

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The origin and evolution of ribonucleotide reduction

Life, 2015-02, Vol.5 (1), p.604-636

2015

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Functional features cause misfolding of the ALS-provoking enzyme SOD1

Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (24), p.9667-9672

2009

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Structural Aspects of N-Glycosylations and the C-terminal Region in Human Glypican-1

The Journal of biological chemistry, 2015-09, Vol.290 (38), p.22991-23008

2015

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Global structural motions from the strain of a single hydrogen bond

Proceedings of the National Academy of Sciences - PNAS, 2013-03, Vol.110 (10), p.3829-3834

2013

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The Coupling between Disulphide Status, Metallation and Dimer Interface Strength in Cu/Zn Superoxide Dismutase

Journal of molecular biology, 2007, Vol.365 (2), p.333-342

2007

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Interactive model building in neutron macromolecular crystallography

Methods in Enzymology, 2020, Vol.634, p.201-224

2020

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Insight into the dimer dissociation process of the Chromobacterium violaceum (S)-selective amine transaminase

Scientific reports, 2019-11, Vol.9 (1), p.16946, Article 16946

2019

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Neutron Crystallographic Studies Reveal Hydrogen Bond and Water-Mediated Interactions between a Carbohydrate-Binding Module and Its Bound Carbohydrate Ligand

Biochemistry (Easton), 2015-10, Vol.54 (42), p.6435-6438

2015

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Phosphorylation of hormone-sensitive lipase by protein kinase A in vitro promotes an increase in its hydrophobic surface area

The FEBS journal, 2009-09, Vol.276 (17), p.4752-4762

2009

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Interplay of halogen bonding and solvation in protein–ligand binding

iScience, 2024-04, Vol.27 (4), p.109636-109636, Article 109636

2024

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Solution Structure of the dATP-Inactivated Class I Ribonucleotide Reductase From Leeuwenhoekiella blandensis by SAXS and Cryo-Electron Microscopy

Frontiers in molecular biosciences, 2021-07, Vol.8, p.713608-713608

2021

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Thermodynamics of protein destabilization in live cells

Interplay between Conformational Entropy and Solvation Entropy in Protein–Ligand Binding

DNA building blocks: keeping control of manufacture

The Carbohydrate-Binding Site in Galectin-3 Is Preorganized To Recognize a Sugarlike Framework of Oxygens: Ultra-High-Resolution Structures and Water Dynamics

Entropy–Entropy Compensation between the Protein, Ligand, and Solvent Degrees of Freedom Fine-Tunes Affinity in Ligand Binding to Galectin-3C

DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously

The engineered CD80 variant fusion therapeutic davoceticept combines checkpoint antagonism with conditional CD28 costimulation for anti-tumor immunity

Structure-Function Analysis of Heterodimer Formation, Oligomerization, and Receptor Binding of the Staphylococcus aureus Bi-component Toxin LukGH

Nucleotide binding to the ATP-cone in anaerobic ribonucleotide reductases allosterically regulates activity by modulating substrate binding

Folding Catalysis by Transient Coordination of Zn2+ to the Cu Ligands of the ALS-Associated Enzyme Cu/Zn Superoxide Dismutase 1

A nucleotide-sensing oligomerization mechanism that controls NrdR-dependent transcription of ribonucleotide reductases

MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM

Structural and Biophysical Characterization of Human EXTL3: Domain Organization, Glycosylation, and Solution Structure

NAD+ pool depletion as a signal for the Rex regulon involved in Streptococcus agalactiae virulence

The origin and evolution of ribonucleotide reduction

Functional features cause misfolding of the ALS-provoking enzyme SOD1

Structural Aspects of N-Glycosylations and the C-terminal Region in Human Glypican-1

Global structural motions from the strain of a single hydrogen bond

The Coupling between Disulphide Status, Metallation and Dimer Interface Strength in Cu/Zn Superoxide Dismutase

Interactive model building in neutron macromolecular crystallography

Insight into the dimer dissociation process of the Chromobacterium violaceum (S)-selective amine transaminase

Neutron Crystallographic Studies Reveal Hydrogen Bond and Water-Mediated Interactions between a Carbohydrate-Binding Module and Its Bound Carbohydrate Ligand

Phosphorylation of hormone-sensitive lipase by protein kinase A in vitro promotes an increase in its hydrophobic surface area

Interplay of halogen bonding and solvation in protein–ligand binding

Solution Structure of the dATP-Inactivated Class I Ribonucleotide Reductase From Leeuwenhoekiella blandensis by SAXS and Cryo-Electron Microscopy

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