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Stabilizing short-lived Schiff base derivatives of 5-aminouracils that activate mucosal-associated invariant T cells

Nature communications, 2017-03, Vol.8 (1), p.14599-14599, Article 14599

2017

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C5aR and C3aR antagonists each inhibit diet‐induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling

The FASEB journal, 2013-02, Vol.27 (2), p.822-831

2013

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Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS

Journal of leukocyte biology, 2010-06, Vol.87 (6), p.1103-1114

2010

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An HDAC6 Inhibitor Confers Protection and Selectively Inhibits B-Cell Infiltration in DSS-Induced Colitis in Mice

The Journal of pharmacology and experimental therapeutics, 2017-01, Vol.360 (1), p.140-151

2017

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Ras-Related Protein Rab5a Regulates Complement C5a Receptor Trafficking, Chemotaxis, and Chemokine Secretion in Human Macrophages

Journal of innate immunity, 2023-01, Vol.15 (1), p.468-484

2023

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Inhibitors of secretory phospholipase A2 group IIA

Current medicinal chemistry, 2005-12, Vol.12 (25), p.3011-3026

Reid, Robert C

2005

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Exploiting a novel conformational switch to control innate immunity mediated by complement protein C3a

Nature communications, 2017-08, Vol.8 (1), p.351-15, Article 351

2017

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Towards isozyme-selective HDAC inhibitors for interrogating disease

Current topics in medicinal chemistry, 2012-08, Vol.12 (14), p.1479-1499

2012

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Temporal perturbation of histone deacetylase activity reveals a requirement for HDAC1–3 in mesendoderm cell differentiation

Cell reports (Cambridge), 2022-05, Vol.39 (7), p.110818-110818, Article 110818

2022

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Alpine Ski Motion Characteristics in Slalom

Frontiers in sports and active living, 2020-03, Vol.2, p.25-25

2020

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Identification of brain metastasis genes and therapeutic evaluation of histone deacetylase inhibitors in a clinically relevant model of breast cancer brain metastasis

Disease models & mechanisms, 2018-07, Vol.11 (7)

2018

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Histone deacetylase inhibitor AR-42 and achiral analogues kill malaria parasites in vitro and in mice

International journal for parasitology -- drugs and drug resistance, 2021-12, Vol.17, p.118-127

2021

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Teacher's guide to ADHD

2012

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Selective Hexapeptide Agonists and Antagonists for Human Complement C3a Receptor

Journal of medicinal chemistry, 2010-07, Vol.53 (13), p.4938-4948

2010

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Histone deacetylase 7 activates 6-phosphogluconate dehydrogenase via an enzyme-independent mechanism that involves the N-terminal protein-protein interaction domain

Biochemical journal, 2024-11, Vol.481 (21), p.1569-1584

2024

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Chemical Approaches to Modulating Complement-Mediated Diseases

Journal of medicinal chemistry, 2018-04, Vol.61 (8), p.3253-3276

2018

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Insecticidal activities of histone deacetylase inhibitors against a dipteran parasite of sheep, Lucilia cuprina

International journal for parasitology -- drugs and drug resistance, 2017-04, Vol.7 (1), p.51-60

2017

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A Potent Human C5a Receptor Antagonist Protects against Disease Pathology in a Rat Model of Inflammatory Bowel Disease

The Journal of immunology (1950), 2003-11, Vol.171 (10), p.5514-5520

2003

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Achiral Derivatives of Hydroxamate AR-42 Potently Inhibit Class I HDAC Enzymes and Cancer Cell Proliferation

Journal of medicinal chemistry, 2020-06, Vol.63 (11), p.5956-5971

2020

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Stereoelectronic Effects Dictate Molecular Conformation and Biological Function of Heterocyclic Amides

Journal of the American Chemical Society, 2014-08, Vol.136 (34), p.11914-11917

2014

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The Role of the N-terminal Domain of the Complement Fragment Receptor C5L2 in Ligand Binding

The Journal of biological chemistry, 2007-02, Vol.282 (6), p.3664-3671

2007

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The histone deacetylase Hdac7 supports LPS‐inducible glycolysis and Il‐1β production in murine macrophages via distinct mechanisms

Journal of leukocyte biology, 2022-02, Vol.111 (2), p.327-336

2022

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HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates

Journal of medicinal chemistry, 2021-02, Vol.64 (4), p.2186-2204

2021

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Potent Cyclic Antagonists of the Complement C5a Receptor on Human Polymorphonuclear Leukocytes. Relationships between Structures and Activity

Molecular pharmacology, 2004-04, Vol.65 (4), p.868-879

2004

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Histone Deacetylase Inhibitors Promote Mitochondrial Reactive Oxygen Species Production and Bacterial Clearance by Human Macrophages

Antimicrobial agents and chemotherapy, 2016-03, Vol.60 (3), p.1521-1529

2016

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Stabilizing short-lived Schiff base derivatives of 5-aminouracils that activate mucosal-associated invariant T cells

C5aR and C3aR antagonists each inhibit diet‐induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling

Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS

An HDAC6 Inhibitor Confers Protection and Selectively Inhibits B-Cell Infiltration in DSS-Induced Colitis in Mice

Ras-Related Protein Rab5a Regulates Complement C5a Receptor Trafficking, Chemotaxis, and Chemokine Secretion in Human Macrophages

Inhibitors of secretory phospholipase A2 group IIA

Exploiting a novel conformational switch to control innate immunity mediated by complement protein C3a

Towards isozyme-selective HDAC inhibitors for interrogating disease

Temporal perturbation of histone deacetylase activity reveals a requirement for HDAC1–3 in mesendoderm cell differentiation

Alpine Ski Motion Characteristics in Slalom

Identification of brain metastasis genes and therapeutic evaluation of histone deacetylase inhibitors in a clinically relevant model of breast cancer brain metastasis

Histone deacetylase inhibitor AR-42 and achiral analogues kill malaria parasites in vitro and in mice

Teacher's guide to ADHD

Selective Hexapeptide Agonists and Antagonists for Human Complement C3a Receptor

Histone deacetylase 7 activates 6-phosphogluconate dehydrogenase via an enzyme-independent mechanism that involves the N-terminal protein-protein interaction domain

Chemical Approaches to Modulating Complement-Mediated Diseases

Insecticidal activities of histone deacetylase inhibitors against a dipteran parasite of sheep, Lucilia cuprina

A Potent Human C5a Receptor Antagonist Protects against Disease Pathology in a Rat Model of Inflammatory Bowel Disease

Achiral Derivatives of Hydroxamate AR-42 Potently Inhibit Class I HDAC Enzymes and Cancer Cell Proliferation

Stereoelectronic Effects Dictate Molecular Conformation and Biological Function of Heterocyclic Amides

The Role of the N-terminal Domain of the Complement Fragment Receptor C5L2 in Ligand Binding

The histone deacetylase Hdac7 supports LPS‐inducible glycolysis and Il‐1β production in murine macrophages via distinct mechanisms

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates

Potent Cyclic Antagonists of the Complement C5a Receptor on Human Polymorphonuclear Leukocytes. Relationships between Structures and Activity

Histone Deacetylase Inhibitors Promote Mitochondrial Reactive Oxygen Species Production and Bacterial Clearance by Human Macrophages

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