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Improving Chimeric Antigen Receptor-Modified T Cell Function by Reversing the Immunosuppressive Tumor Microenvironment of Pancreatic Cancer

Molecular therapy, 2017-01, Vol.25 (1), p.249-258

2017

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Off-the-Shelf Virus-Specific T Cells to Treat BK Virus, Human Herpesvirus 6, Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections After Allogeneic Hematopoietic Stem-Cell Transplantation

Journal of clinical oncology, 2017-11, Vol.35 (31), p.3547-3557

2017

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Enhancing the Potency and Specificity of Engineered T Cells for Cancer Treatment

Cancer discovery, 2018-08, Vol.8 (8), p.972-987

2018

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Activity of broad-spectrum T cells as treatment for AdV, EBV, CMV, BKV, and HHV6 infections after HSCT

Science translational medicine, 2014-06, Vol.6 (242), p.242ra83

2014

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Posoleucel, an Allogeneic, Off-the-Shelf Multivirus-Specific T-Cell Therapy, for the Treatment of Refractory Viral Infections in the Post-HCT Setting

Clinical cancer research, 2023-01, Vol.29 (2), p.324-330

2023

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Allogeneic, off-the-shelf, SARS-CoV-2-specific T cells (ALVR109) for the treatment of COVID-19 in high-risk patients

Haematologica (Roma), 2023-07, Vol.108 (7), p.1840-1850

2023

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Phenotypic and functional characterization of posoleucel, a multivirus-specific T cell therapy for the treatment and prevention of viral infections in immunocompromised patients

Cytotherapy (Oxford, England), 2024-08, Vol.26 (8), p.869-877

2024

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Infusion of cytotoxic T lymphocytes for the treatment of viral infections in hematopoetic stem cell transplant patients

Current opinion in infectious diseases, 2018-08, Vol.31 (4), p.292-300

2018

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Multicenter study of banked third-party virus-specific T cells to treat severe viral infections after hematopoietic stem cell transplantation

Blood, 2013-06, Vol.121 (26), p.5113-5123

2013

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T cell immune profiling of respiratory syncytial virus for the development of a targeted immunotherapy

British journal of haematology, 2023-08, Vol.202 (4), p.874-878

2023

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Longitudinal analysis of the evolution of cellular immunity to SARS-CoV-2 induced by infection and vaccination

Haematologica (Roma), 2023-07, Vol.108 (7), p.1934-1939

2023

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Fine-tuning the CAR spacer improves T-cell potency

Oncoimmunology, 2016-12, Vol.5 (12), p.e1253656-e1253656

2016

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Antiviral T-cell therapy

Immunological reviews, 2014-03, Vol.258 (1), p.12-29

2014

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Rapid generation of multivirus-specific T lymphocytes for the prevention and treatment of respiratory viral infections

Haematologica (Roma), 2020-01, Vol.105 (1), p.235-243

2020

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Rapidly generated multivirus-specific cytotoxic T lymphocytes for the prophylaxis and treatment of viral infections

Molecular therapy, 2012-08, Vol.20 (8), p.1622-1632

2012

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Vaccination Targeting Native Receptors to Enhance the Function and Proliferation of Chimeric Antigen Receptor (CAR)-Modified T Cells

Clinical cancer research, 2017-07, Vol.23 (14), p.3499-3509

2017

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Reversal of Tumor Immune Inhibition Using a Chimeric Cytokine Receptor

Molecular therapy, 2014-06, Vol.22 (6), p.1211-1220

2014

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CAR T cell therapy for breast cancer: harnessing the tumor milieu to drive T cell activation

Journal for immunotherapy of cancer, 2018-05, Vol.6 (1), p.34-34, Article 34

2018

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Clinical effects of administering leukemia-specific donor T cells to patients with AML/MDS after allogeneic transplant

Blood, 2021-05, Vol.137 (19), p.2585-2597

2021

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Safety and clinical efficacy of rapidly-generated trivirus-directed T cells as treatment for adenovirus, EBV, and CMV infections after allogeneic hematopoietic stem cell transplant

Molecular therapy, 2013-11, Vol.21 (11), p.2113-2121

2013

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Is cancer gene therapy an empty suit?

The lancet oncology, 2013-10, Vol.14 (11), p.e447-e456

2013

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Targeting IDH2R140Q and other neoantigens in acute myeloid leukemia

Blood, 2024-04, Vol.143 (17), p.1726-1737

2024

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Long-term outcome after haploidentical stem cell transplant and infusion of T cells expressing the inducible caspase 9 safety transgene

Blood, 2014-06, Vol.123 (25), p.3895-3905

2014

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T-Cell Therapy for Lymphoma Using Nonengineered Multiantigen-Targeted T Cells Is Safe and Produces Durable Clinical Effects

Journal of clinical oncology, 2021-05, Vol.39 (13), p.1415-1425

2021

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Improving Chimeric Antigen Receptor-Modified T Cell Function by Reversing the Immunosuppressive Tumor Microenvironment of Pancreatic Cancer

Off-the-Shelf Virus-Specific T Cells to Treat BK Virus, Human Herpesvirus 6, Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections After Allogeneic Hematopoietic Stem-Cell Transplantation

Enhancing the Potency and Specificity of Engineered T Cells for Cancer Treatment

Activity of broad-spectrum T cells as treatment for AdV, EBV, CMV, BKV, and HHV6 infections after HSCT

Posoleucel, an Allogeneic, Off-the-Shelf Multivirus-Specific T-Cell Therapy, for the Treatment of Refractory Viral Infections in the Post-HCT Setting

Allogeneic, off-the-shelf, SARS-CoV-2-specific T cells (ALVR109) for the treatment of COVID-19 in high-risk patients

Phenotypic and functional characterization of posoleucel, a multivirus-specific T cell therapy for the treatment and prevention of viral infections in immunocompromised patients

Infusion of cytotoxic T lymphocytes for the treatment of viral infections in hematopoetic stem cell transplant patients

Multicenter study of banked third-party virus-specific T cells to treat severe viral infections after hematopoietic stem cell transplantation

T cell immune profiling of respiratory syncytial virus for the development of a targeted immunotherapy

Longitudinal analysis of the evolution of cellular immunity to SARS-CoV-2 induced by infection and vaccination

Fine-tuning the CAR spacer improves T-cell potency

Antiviral T-cell therapy

Rapid generation of multivirus-specific T lymphocytes for the prevention and treatment of respiratory viral infections

Rapidly generated multivirus-specific cytotoxic T lymphocytes for the prophylaxis and treatment of viral infections

Vaccination Targeting Native Receptors to Enhance the Function and Proliferation of Chimeric Antigen Receptor (CAR)-Modified T Cells

Reversal of Tumor Immune Inhibition Using a Chimeric Cytokine Receptor

CAR T cell therapy for breast cancer: harnessing the tumor milieu to drive T cell activation

Clinical effects of administering leukemia-specific donor T cells to patients with AML/MDS after allogeneic transplant

Safety and clinical efficacy of rapidly-generated trivirus-directed T cells as treatment for adenovirus, EBV, and CMV infections after allogeneic hematopoietic stem cell transplant

Is cancer gene therapy an empty suit?

Targeting IDH2R140Q and other neoantigens in acute myeloid leukemia

LOAd703, an oncolytic virus-based immunostimulatory gene therapy, combined with chemotherapy for unresectable or metastatic pancreatic cancer (LOKON001): results from arm 1 of a non-randomised, single-centre, phase 1/2 study

Long-term outcome after haploidentical stem cell transplant and infusion of T cells expressing the inducible caspase 9 safety transgene

T-Cell Therapy for Lymphoma Using Nonengineered Multiantigen-Targeted T Cells Is Safe and Produces Durable Clinical Effects

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