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A Drug Resistance Mutation in the Inhibitor Binding Pocket of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Impairs DNA Synthesis and RNA Degradation

Biochemistry (Easton), 1996-07, Vol.35 (30), p.9737-9745

1996

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Oxazolidinones: a new class of antibacterials

Current Opinion in Pharmacology, 2001-10, Vol.1 (5), p.470-476

2001

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Steady-state kinetic studies with the non-nucleoside HIV-1 reverse transcriptase inhibitor U-87201E

The Journal of biological chemistry, 1993-03, Vol.268 (9), p.6119-6124

1993

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(Alkylamino) piperidine bis(heteroaryl)piperizine analogs are potent, broad-spectrum nonnucleoside reverse transcriptase inhibitors of drug-resistant isolates of human immunodeficiency virus type 1 (HIV-1) and select for drug-resistant variants of HIV-1IIIB with reduced replication phenotypes

Journal of Virology, 1996-06, Vol.70 (6), p.3698-3705

1996

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Inhibition of the protease of human immunodeficiency virus blocks replication and infectivity of the virus in chronically infected macrophages

The Journal of infectious diseases, 1993-11, Vol.168 (5), p.1148-1156

1993

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Characterization of the p68/p58 Heterodimer of Human Immunodeficiency Virus Type 2 Reverse Transcriptase

Biochemistry (Easton), 1996-02, Vol.35 (6), p.1911-1917

1996

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The Differential Processing of Homodimers of Reverse Transcriptases from Human Immunodeficiency Viruses Type 1 and 2 Is a Consequence of the Distinct Specificities of the Viral Proteases

The Journal of biological chemistry, 1995-06, Vol.270 (22), p.13573-13579

1995

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Mechanism of resistance to U-90152S and sensitization to L-697,661 by a proline to leucine change at residue 236 of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase

FEBS letters, 1995-02, Vol.359 (2), p.233-238

1995

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An active recombinant p15 RNase H domain is functionally distinct from the RNase H domain associated with human immunodeficiency virus type 1 reverse transcriptase

The Journal of biological chemistry, 1994-08, Vol.269 (34), p.21741-21747

1994

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Inhibitors of the protease from human immunodeficiency virus: synthesis, enzyme inhibition, and antiviral activity of a series of compounds containing the dihydroxyethylene transition-state isostere

Journal of medicinal chemistry, 1993-04, Vol.36 (8), p.941-952

1993

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Simultaneous mutations at Tyr-181 and Tyr-188 in HIV-1 reverse transcriptase prevents inhibition of RNA-dependent DNA polymerase activity by the bisheteroarylpiperazine (BHAP) U-90152s

FEBS letters, 1995-08, Vol.370 (1), p.59-62

1995

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Expression and characterization of chimeric rDNA proteins engineered for purification and enzymatic cleavage

Protein expression and purification, 1991-04, Vol.2 (2), p.205-213

1991

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Effects of a soluble CD4 and CD4- Pseudomonas exotoxin A chimeric protein on human peripheral blood lymphocytes: Lymphocyte activation and anti-HIV activity in vitro

Antiviral research, 1991-10, Vol.16 (3), p.267-279

1991

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4-aminoazobenzene and N,N-dimethyl-4-aminoazobenzene as equipotent hepatic carcinogens in male C57BL/6 X C3H/He F1 mice and characterization of N-(Deoxyguanosin-8-yl)-4-aminoazobenzene as the major persistent hepatic DNA-bound dye in these mice

Cancer research (Chicago, Ill.), 1984-06, Vol.44 (6), p.2540

1984

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The lack of PDGF-stimulated PGE2 release from ras-transformed NIH-3T3 cells results from reduced phospholipase C but not phospholipase A2 activity

Biochemical and biophysical research communications, 1987-06, Vol.145 (3), p.1254-1259

1987

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Resolution of microheterogeneity associated with recombinant HIV-1 heterodimeric reverse transcriptase

Protein expression and purification, 1992, Vol.3 (2), p.151-159

1992

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A bacteriophage transcription terminator permits the cloning of a mammalian expression vector carrying the human preprorenin gene in E. coli

Biochemical and biophysical research communications, 1987-03, Vol.143 (2), p.593-599

1987

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The lack of PDGF-stimulated PGE 2 release from [formula omitted]-transformed NIH-3T3 cells results from reduced phospholipase C but not phospholipase A 2 activity

Biochemical and biophysical research communications, 1987, Vol.145 (3), p.1254-1259

1987

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Rapid release of carcinogen-guanine adducts from DNA after reaction with N-acetoxy-2-acetylaminofluorene or N-benzoyloxy-N-methyl-4-aminoazobenzene

Carcinogenesis (New York), 1982, Vol.3 (1), p.81-88

1982

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Purification of an active monomeric recombinant HIV-1 trans-activator

Protein expression and purification, 1992-04, Vol.3 (2), p.126-133

1992

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THE NUCLEIC ACID ADDUCTS OF THE HEPATOCARCINOGENIC AROMATIC AMINES AND AMIDES RELATED TO N-METHYL-4-AMINOAZOBENZENE AND N-HYDROXY-2-ACETYLAMINOFLUORENE

TARPLEY, W GARY

1982

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Adducts from the reaction of N-benzoyloxy-N-methyl-4-aminoazobenzene with deoxyguanosine or DNA in vitro and from hepatic DNA of mice treated with N-methyl- or N,N-dimethyl-4-aminoazobenzene

Cancer research (Chicago, Ill.), 1980-07, Vol.40 (7), p.2493

1980

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The Location of v-src in a Retrovirus Vector Determines Whether the Virus Is Toxic or Transforming

Molecular and cellular biology, 1984-12, Vol.4 (12), p.2653-2660

1984

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Isolation and Characterization of Human Prorenin Secreted from Murine Cells Transformed with a Bovine Papilloma Virus-Preprorenin Expression Vector

Bio/technology (New York, N.Y. 1983), 1987-07, Vol.5 (7), p.705-709

1987

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A Drug Resistance Mutation in the Inhibitor Binding Pocket of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Impairs DNA Synthesis and RNA Degradation

Oxazolidinones: a new class of antibacterials

(−)-6-Chloro-2-[(1-furo[2,3-c]pyridin-5-ylethyl)thio]-4-pyrimidinamine, PNU-142721, a New Broad Spectrum HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor

Steady-state kinetic studies with the non-nucleoside HIV-1 reverse transcriptase inhibitor U-87201E

(Alkylamino) piperidine bis(heteroaryl)piperizine analogs are potent, broad-spectrum nonnucleoside reverse transcriptase inhibitors of drug-resistant isolates of human immunodeficiency virus type 1 (HIV-1) and select for drug-resistant variants of HIV-1IIIB with reduced replication phenotypes

Inhibition of the protease of human immunodeficiency virus blocks replication and infectivity of the virus in chronically infected macrophages

Characterization of the p68/p58 Heterodimer of Human Immunodeficiency Virus Type 2 Reverse Transcriptase

The Differential Processing of Homodimers of Reverse Transcriptases from Human Immunodeficiency Viruses Type 1 and 2 Is a Consequence of the Distinct Specificities of the Viral Proteases

Mechanism of resistance to U-90152S and sensitization to L-697,661 by a proline to leucine change at residue 236 of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase

An active recombinant p15 RNase H domain is functionally distinct from the RNase H domain associated with human immunodeficiency virus type 1 reverse transcriptase

Inhibitors of the protease from human immunodeficiency virus: synthesis, enzyme inhibition, and antiviral activity of a series of compounds containing the dihydroxyethylene transition-state isostere

Simultaneous mutations at Tyr-181 and Tyr-188 in HIV-1 reverse transcriptase prevents inhibition of RNA-dependent DNA polymerase activity by the bisheteroarylpiperazine (BHAP) U-90152s

Expression and characterization of chimeric rDNA proteins engineered for purification and enzymatic cleavage

Effects of a soluble CD4 and CD4- Pseudomonas exotoxin A chimeric protein on human peripheral blood lymphocytes: Lymphocyte activation and anti-HIV activity in vitro

4-aminoazobenzene and N,N-dimethyl-4-aminoazobenzene as equipotent hepatic carcinogens in male C57BL/6 X C3H/He F1 mice and characterization of N-(Deoxyguanosin-8-yl)-4-aminoazobenzene as the major persistent hepatic DNA-bound dye in these mice

The lack of PDGF-stimulated PGE2 release from ras-transformed NIH-3T3 cells results from reduced phospholipase C but not phospholipase A2 activity

Resolution of microheterogeneity associated with recombinant HIV-1 heterodimeric reverse transcriptase

A bacteriophage transcription terminator permits the cloning of a mammalian expression vector carrying the human preprorenin gene in E. coli

The lack of PDGF-stimulated PGE 2 release from [formula omitted]-transformed NIH-3T3 cells results from reduced phospholipase C but not phospholipase A 2 activity

Rapid release of carcinogen-guanine adducts from DNA after reaction with N-acetoxy-2-acetylaminofluorene or N-benzoyloxy-N-methyl-4-aminoazobenzene

Purification of an active monomeric recombinant HIV-1 trans-activator

THE NUCLEIC ACID ADDUCTS OF THE HEPATOCARCINOGENIC AROMATIC AMINES AND AMIDES RELATED TO N-METHYL-4-AMINOAZOBENZENE AND N-HYDROXY-2-ACETYLAMINOFLUORENE

Adducts from the reaction of N-benzoyloxy-N-methyl-4-aminoazobenzene with deoxyguanosine or DNA in vitro and from hepatic DNA of mice treated with N-methyl- or N,N-dimethyl-4-aminoazobenzene

The Location of v-src in a Retrovirus Vector Determines Whether the Virus Is Toxic or Transforming

Isolation and Characterization of Human Prorenin Secreted from Murine Cells Transformed with a Bovine Papilloma Virus-Preprorenin Expression Vector

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