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High-throughput screening platform for natural product-based drug discovery against 3 neglected tropical diseases: human African trypanosomiasis, leishmaniasis, and Chagas disease

Journal of biomolecular screening, 2015-01, Vol.20 (1), p.82-91

2015

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Mechanisms of experimental resistance of Leishmania to miltefosine: Implications for clinical use

Drug resistance updates, 2006-02, Vol.9 (1), p.26-39

2006

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Modulation by flavonoids of cell multidrug resistance mediated by P-glycoprotein and related ABC transporters

Cellular and molecular life sciences : CMLS, 2002-02, Vol.59 (2), p.307-322

2002

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Dihidro-β-Agarofuran Sesquiterpenes: A New Class of Reversal Agents of the Multidrug Resistance Phenotype Mediated by P-Glycoprotein in the Protozoan Parasite Leishmania

Current pharmaceutical design, 2005-09, Vol.11 (24), p.3125-3139

2005

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Multidrug resistance phenotype mediated by the P-glycoprotein-like transporter in Leishmania: a search for reversal agents

Current drug targets, 2002-08, Vol.3 (4), p.311-333

2002

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Correlation between the Affinity of Flavonoids Binding to the Cytosolic Site of Leishmania tropica Multidrug Transporter and Their Efficiency To Revert Parasite Resistance to Daunomycin

Biochemistry (Easton), 1999-02, Vol.38 (6), p.1736-1743

1999

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Leishmania donovani Resistance to Miltefosine Involves a Defective Inward Translocation of the Drug

Antimicrobial Agents and Chemotherapy, 2003-08, Vol.47 (8), p.2397-2403

2003

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Functional cloning of the miltefosine transporter. A novel P-type phospholipid translocase from Leishmania involved in drug resistance

The Journal of biological chemistry, 2003-12, Vol.278 (50), p.49965-49971

2003

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RU49953: a non-hormonal steroid derivative that potently inhibits P-glycoprotein and reverts cellular multidrug resistance

Cellular and molecular life sciences : CMLS, 2003-03, Vol.60 (3), p.526-535

2003

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Identification of specific reversal agents for Leishmania ABCI4-mediated antimony resistance by flavonoid and trolox derivative screening

Journal of antimicrobial chemotherapy, 2014-03, Vol.69 (3), p.664-672

2014

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Molecular characterization of a P-glycoprotein-related tcpgp2 gene in Trypanosoma cruzi

Molecular and biochemical parasitology, 1996-01, Vol.75 (2), p.145-157

1996

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Reversion of human Pgp-dependent multidrug resistance by new sesquiterpenes from Zinowiewia costaricensis

Journal of medicinal chemistry, 2005-06, Vol.48 (13), p.4266-4275

2005

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The overexpression of an intracellular ABCA-like transporter alters phospholipid trafficking in Leishmania

Biochemical and biophysical research communications, 2005-04, Vol.330 (1), p.349-355

2005

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The overexpression of a new ABC transporter in Leishmania is related to phospholipid trafficking and reduced infectivity

Biochimica et biophysica acta, 2003-06, Vol.1612 (2), p.195-207

2003

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Connective Tissue Reflex Massage for Type 2 Diabetic Patients with Peripheral Arterial Disease : Randomized Controlled Trial

Evidence-based complementary and alternative medicine, 2011-01, Vol.2011 (2011), p.1-12

2011

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Functional expression of a multidrug P-glycoprotein transporter of Leishmania

Biochemical and biophysical research communications, 2005-04, Vol.329 (2), p.502-507

2005

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Different catalytic activities of hexokinase and phosphofructokinase in wild type and glucantime-resistant Leishmania promastigotes appears not causatively related to resistance

European journal of protistology, 1999-10, Vol.35 (3), p.338-341

1999

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Insights into the molecular mechanism of action of Celastraceae sesquiterpenes as specific, non-transported inhibitors of human P-glycoprotein

Biochimica et biophysica acta, 2006, Vol.1758 (1), p.98-110

2006

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Rapid transport of phospholipids across the plasma membrane of Leishmania infantum

Biochemical and biophysical research communications, 2003-06, Vol.306 (1), p.250-255

2003

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Evolutionary relationships in Trypanosoma cruzi: molecular phylogenetics supports the existence of a new major lineage of strains

Gene, 2000-04, Vol.246 (1), p.331-338

2000

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A pteridine reductase gene ptr1 contiguous to a P-glycoprotein confers resistance to antifolates in Trypanosoma cruzi

Molecular and biochemical parasitology, 1997-12, Vol.90 (2), p.525-535

1997

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Pyridinium azolate betaines and their derivatives: a new class of antiprotozoal agents

European journal of medicinal chemistry, 1990-05, Vol.25 (4), p.309-319

1990

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The invasion mechanism of the metacyclic forms of Trypanosoma cruzi in nonphagocytic host cells

Biological research, 1993, Vol.26 (1-2), p.19-26

1993

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The UpPriority tool supported prioritization processes for updating clinical guideline questions

Journal of clinical epidemiology, 2021-11, Vol.139, p.149-159

2021

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ABC transporters in the protozoan parasite Leishmania

International microbiology, 2001-09, Vol.4 (3), p.159-166

2001

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High-throughput screening platform for natural product-based drug discovery against 3 neglected tropical diseases: human African trypanosomiasis, leishmaniasis, and Chagas disease

Mechanisms of experimental resistance of Leishmania to miltefosine: Implications for clinical use

Modulation by flavonoids of cell multidrug resistance mediated by P-glycoprotein and related ABC transporters

Dihidro-β-Agarofuran Sesquiterpenes: A New Class of Reversal Agents of the Multidrug Resistance Phenotype Mediated by P-Glycoprotein in the Protozoan Parasite Leishmania

Multidrug resistance phenotype mediated by the P-glycoprotein-like transporter in Leishmania: a search for reversal agents

Correlation between the Affinity of Flavonoids Binding to the Cytosolic Site of Leishmania tropica Multidrug Transporter and Their Efficiency To Revert Parasite Resistance to Daunomycin

Leishmania donovani Resistance to Miltefosine Involves a Defective Inward Translocation of the Drug

Functional cloning of the miltefosine transporter. A novel P-type phospholipid translocase from Leishmania involved in drug resistance

RU49953: a non-hormonal steroid derivative that potently inhibits P-glycoprotein and reverts cellular multidrug resistance

Identification of specific reversal agents for Leishmania ABCI4-mediated antimony resistance by flavonoid and trolox derivative screening

Molecular characterization of a P-glycoprotein-related tcpgp2 gene in Trypanosoma cruzi

Reversion of human Pgp-dependent multidrug resistance by new sesquiterpenes from Zinowiewia costaricensis

The overexpression of an intracellular ABCA-like transporter alters phospholipid trafficking in Leishmania

The overexpression of a new ABC transporter in Leishmania is related to phospholipid trafficking and reduced infectivity

Connective Tissue Reflex Massage for Type 2 Diabetic Patients with Peripheral Arterial Disease : Randomized Controlled Trial

Functional expression of a multidrug P-glycoprotein transporter of Leishmania

Different catalytic activities of hexokinase and phosphofructokinase in wild type and glucantime-resistant Leishmania promastigotes appears not causatively related to resistance

Insights into the molecular mechanism of action of Celastraceae sesquiterpenes as specific, non-transported inhibitors of human P-glycoprotein

Rapid transport of phospholipids across the plasma membrane of Leishmania infantum

Evolutionary relationships in Trypanosoma cruzi: molecular phylogenetics supports the existence of a new major lineage of strains

A pteridine reductase gene ptr1 contiguous to a P-glycoprotein confers resistance to antifolates in Trypanosoma cruzi

Pyridinium azolate betaines and their derivatives: a new class of antiprotozoal agents

The invasion mechanism of the metacyclic forms of Trypanosoma cruzi in nonphagocytic host cells

The UpPriority tool supported prioritization processes for updating clinical guideline questions

ABC transporters in the protozoan parasite Leishmania

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