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DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis

eLife, 2013-04, Vol.2, p.e00534

2013

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Antibody diversification by somatic mutation: from Burnet onwards

Immunology and cell biology, 2008-02, Vol.86 (2), p.124-132

Neuberger, Michael S

2008

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Altering the spectrum of immunoglobulin V gene somatic hypermutation by modifying the active site of AID

The Journal of experimental medicine, 2010-01, Vol.207 (1), p.141-153

2010

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The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2-/- ung-/- mice

The Journal of experimental medicine, 2006-09, Vol.203 (9), p.2085-2094

2006

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Cytoplasmic activation-induced cytidine deaminase (AID) exists in stoichiometric complex with translation elongation factor 1α (eEF1A)

Proceedings of the National Academy of Sciences - PNAS, 2011-11, Vol.108 (45), p.18366-18371

2011

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DNA Deamination Mediates Innate Immunity to Retroviral Infection

Cell, 2003-06, Vol.113 (6), p.803-809

2003

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Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase

Nature (London), 2002-09, Vol.419 (6902), p.43-48

2002

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stability of AID and its function in class-switching are critically sensitive to the identity of its nuclear-export sequence

Proceedings of the National Academy of Sciences - PNAS, 2009-04, Vol.106 (16), p.6736-6741

2009

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Interaction between Antibody-Diversification Enzyme AID and Spliceosome-Associated Factor CTNNBL1

Molecular cell, 2008-08, Vol.31 (4), p.474-484

2008

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Mouse APOBEC3 Restricts Friend Leukemia Virus Infection and Pathogenesis In Vivo

Journal of Virology, 2008-11, Vol.82 (22), p.10998-11008

2008

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The AKV Murine Leukemia Virus Is Restricted and Hypermutated by Mouse APOBEC3

Journal of Virology, 2009-11, Vol.83 (22), p.11550-11559

2009

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DNA Deamination in Immunity: AID in the Context of Its APOBEC Relatives

AID for Immunoglobulin Diversity, 2007, Vol.94, p.37-73

2007

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Affinity Dependence of the B Cell Response to Antigen: A Threshold, a Ceiling, and the Importance of Off-Rate

Immunity (Cambridge, Mass.), 1998-06, Vol.8 (6), p.751-759

1998

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Human APOBEC3G Can Restrict Retroviral Infection in Avian Cells and Acts Independently of both UNG and SMUG1

Journal of Virology, 2008-05, Vol.82 (9), p.4660-4664

2008

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TdT-Accessible Breaks Are Scattered over the Immunoglobulin V Domain in a Constitutively Hypermutating B Cell Line

Immunity (Cambridge, Mass.), 1998-12, Vol.9 (6), p.859-869

1998

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Uracil excision by endogenous SMUG1 glycosylase promotes efficient Ig class switching and impacts on A:T substitutions during somatic mutation

European journal of immunology, 2014-07, Vol.44 (7), p.1925-1935

2014

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Hyperresponsive B Cells in CD22-Deficient Mice

Science (American Association for the Advancement of Science), 1996-11, Vol.274 (5288), p.798-801

1996

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REG-γ associates with and modulates the abundance of nuclear activation-induced deaminase

The Journal of experimental medicine, 2011-11, Vol.208 (12), p.2385-2391

2011

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Both DNA Strands of Antibody Genes are Hypermutation Targets

Proceedings of the National Academy of Sciences - PNAS, 1998-07, Vol.95 (15), p.8791-8794

1998

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Immunoglobulin gene conversion in chicken DT40 cells largely proceeds through an abasic site intermediate generated by excision of the uracil produced by AID‐mediated deoxycytidine deamination

European journal of immunology, 2004-02, Vol.34 (2), p.504-508

2004

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AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

Nature (London), 2002-07, Vol.418 (6893), p.99-104

2002

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B cells acquire antigen from target cells after synapse formation

Nature (London), 2001-05, Vol.411 (6836), p.489-494

2001

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Targeted Gene Disruption Reveals a Role for Natural Secretory IgM in the Maturation of the Primary Immune Response

Proceedings of the National Academy of Sciences - PNAS, 1998-08, Vol.95 (17), p.10089-10093

1998

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Somatic hypermutation: activation-induced deaminase for C/G followed by polymerase eta for A/T

The Journal of experimental medicine, 2007-01, Vol.204 (1), p.7-10

2007

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Early-onset lymphoma and extensive embryonic apoptosis in two domain-specific Fen1 mice mutants

Cancer research (Chicago, Ill.), 2008-06, Vol.68 (12), p.4571-4579

2008

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DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis

Antibody diversification by somatic mutation: from Burnet onwards

Altering the spectrum of immunoglobulin V gene somatic hypermutation by modifying the active site of AID

The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2-/- ung-/- mice

Cytoplasmic activation-induced cytidine deaminase (AID) exists in stoichiometric complex with translation elongation factor 1α (eEF1A)

DNA Deamination Mediates Innate Immunity to Retroviral Infection

Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase

stability of AID and its function in class-switching are critically sensitive to the identity of its nuclear-export sequence

Interaction between Antibody-Diversification Enzyme AID and Spliceosome-Associated Factor CTNNBL1

Mouse APOBEC3 Restricts Friend Leukemia Virus Infection and Pathogenesis In Vivo

The AKV Murine Leukemia Virus Is Restricted and Hypermutated by Mouse APOBEC3

DNA Deamination in Immunity: AID in the Context of Its APOBEC Relatives

Affinity Dependence of the B Cell Response to Antigen: A Threshold, a Ceiling, and the Importance of Off-Rate

Human APOBEC3G Can Restrict Retroviral Infection in Avian Cells and Acts Independently of both UNG and SMUG1

TdT-Accessible Breaks Are Scattered over the Immunoglobulin V Domain in a Constitutively Hypermutating B Cell Line

Uracil excision by endogenous SMUG1 glycosylase promotes efficient Ig class switching and impacts on A:T substitutions during somatic mutation

Hyperresponsive B Cells in CD22-Deficient Mice

REG-γ associates with and modulates the abundance of nuclear activation-induced deaminase

Both DNA Strands of Antibody Genes are Hypermutation Targets

Immunoglobulin gene conversion in chicken DT40 cells largely proceeds through an abasic site intermediate generated by excision of the uracil produced by AID‐mediated deoxycytidine deamination

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

B cells acquire antigen from target cells after synapse formation

Targeted Gene Disruption Reveals a Role for Natural Secretory IgM in the Maturation of the Primary Immune Response

Somatic hypermutation: activation-induced deaminase for C/G followed by polymerase eta for A/T

Early-onset lymphoma and extensive embryonic apoptosis in two domain-specific Fen1 mice mutants

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