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ATR inhibition enables complete tumour regression in ALK-driven NB mouse models

Nature communications, 2021-11, Vol.12 (1), p.6813-6813, Article 6813

2021

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ALK signaling primes the DNA damage response sensitizing ALK-driven neuroblastoma to therapeutic ATR inhibition

Proceedings of the National Academy of Sciences - PNAS, 2024-01, Vol.121 (1), p.e2315242121-e2315242121

2024

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Quantification of Neoantigen-Mediated Immunoediting in Cancer Evolution-Letter

Cancer research (Chicago, Ill.), 2023-03, Vol.83 (6), p.971-972

2023

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Clinical response of the novel activating ALK-I1171T mutation in neuroblastoma to the ALK inhibitor ceritinib

Cold Spring Harbor molecular case studies, 2018-08, Vol.4 (4), p.a002550

2018

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Low immunogenicity of common cancer hot spot mutations resulting in false immunogenic selection signals

PLoS genetics, 2021-02, Vol.17 (2), p.e1009368-e1009368

2021

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Benchmark of tools for in silico prediction of MHC class I and class II genotypes from NGS data

BMC genomics, 2023-05, Vol.24 (1), p.247-247, Article 247

2023

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Recurrent promoter mutations in melanoma are defined by an extended context-specific mutational signature

PLoS genetics, 2017-05, Vol.13 (5), p.e1006773-e1006773

2017

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Somatic Mutation Patterns in Hemizygous Genomic Regions Unveil Purifying Selection during Tumor Evolution

PLoS genetics, 2016-12, Vol.12 (12), p.e1006506-e1006506

2016

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Elevated pyrimidine dimer formation at distinct genomic bases underlies promoter mutation hotspots in UV-exposed cancers

PLoS genetics, 2018-12, Vol.14 (12), p.e1007849-e1007849

2018

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MHC class II genotypes are independent predictors of anti-PD1 immunotherapy response in melanoma

Communications medicine, 2024-09, Vol.4 (1), p.184-8, Article 184

2024

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Glycine and glycine receptor signalling in non-neuronal cells

Frontiers in molecular neuroscience, 2009-01, Vol.2, p.9-9

2009

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ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression

Proceedings of the National Academy of Sciences - PNAS, 2023-02, Vol.120 (8), p.e2216479120-e2216479120

2023

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Mutational Signatures Are Critical for Proper Estimation of Purifying Selection Pressures in Cancer Somatic Mutation Data When Using the dN/dS Metric

Frontiers in genetics, 2017-06, Vol.8 (JUN), p.74-74

2017

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Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events

Nature communications, 2016-10, Vol.7 (1), p.13197-13197, Article 13197

2016

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A clinically annotated post-mortem approach to study multi-organ somatic mutational clonality in normal tissues

Scientific reports, 2022-06, Vol.12 (1), p.10322-10322, Article 10322

2022

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A systematic analysis of immune escape signals in the primary and metastatic tumor genome

Nature genetics, 2023-05, Vol.55 (5), p.728-729

Van den Eynden, Jimmy

2023

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Cancer evolution A systematic analysis of immune escape signals in the primary and metastatic tumor genome

Nature genetics, 2023-05, Vol.55 (5), p.728-729

Van den Eynden, Jimmy

2023

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11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in Neuroblastoma

Cell reports (Cambridge), 2020-09, Vol.32 (12), p.108171-108171, Article 108171

2020

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Cancer genomics at the edge of public health and precision medicine in Belgium: A national perspective

Journal of clinical oncology, 2018-05, Vol.36 (15_suppl), p.e18543-e18543

Van den Bulcke, Marc

2018

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Loss of RET Promotes Mesenchymal Identity in Neuroblastoma Cells

Cancers, 2021-04, Vol.13 (8), p.1909

2021

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Network-Based Analysis to Identify Drivers of Metastatic Prostate Cancer Using GoNetic

Cancers, 2021-10, Vol.13 (21), p.5291

2021

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Pathway Relevance Ranking for Tumor Samples through Network-Based Data Integration

PloS one, 2015-07, Vol.10 (7), p.e0133503

2015

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An antisense RNA capable of modulating the expression of the tumor suppressor microRNA-34a

Cell death & disease, 2018-07, Vol.9 (7), p.736-15, Article 736

2018

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Evaluation of anatomy based reconstruction for partial volume correction in brain FDG-PET

NeuroImage (Orlando, Fla.), 2004-09, Vol.23 (1), p.305-317

2004

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The inhibitory neurotransmitter glycine modulates macrophage activity by activation of neutral amino acid transporters

Journal of neuroscience research, 2010-08, Vol.88 (11), p.2420-2430

2010

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ATR inhibition enables complete tumour regression in ALK-driven NB mouse models

ALK signaling primes the DNA damage response sensitizing ALK-driven neuroblastoma to therapeutic ATR inhibition

Quantification of Neoantigen-Mediated Immunoediting in Cancer Evolution-Letter

Clinical response of the novel activating ALK-I1171T mutation in neuroblastoma to the ALK inhibitor ceritinib

Low immunogenicity of common cancer hot spot mutations resulting in false immunogenic selection signals

Benchmark of tools for in silico prediction of MHC class I and class II genotypes from NGS data

Recurrent promoter mutations in melanoma are defined by an extended context-specific mutational signature

Somatic Mutation Patterns in Hemizygous Genomic Regions Unveil Purifying Selection during Tumor Evolution

Elevated pyrimidine dimer formation at distinct genomic bases underlies promoter mutation hotspots in UV-exposed cancers

MHC class II genotypes are independent predictors of anti-PD1 immunotherapy response in melanoma

Glycine and glycine receptor signalling in non-neuronal cells

ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression

Mutational Signatures Are Critical for Proper Estimation of Purifying Selection Pressures in Cancer Somatic Mutation Data When Using the dN/dS Metric

Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events

A clinically annotated post-mortem approach to study multi-organ somatic mutational clonality in normal tissues

A systematic analysis of immune escape signals in the primary and metastatic tumor genome

Cancer evolution A systematic analysis of immune escape signals in the primary and metastatic tumor genome

11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in Neuroblastoma

Cancer genomics at the edge of public health and precision medicine in Belgium: A national perspective

Loss of RET Promotes Mesenchymal Identity in Neuroblastoma Cells

Network-Based Analysis to Identify Drivers of Metastatic Prostate Cancer Using GoNetic

Pathway Relevance Ranking for Tumor Samples through Network-Based Data Integration

An antisense RNA capable of modulating the expression of the tumor suppressor microRNA-34a

Evaluation of anatomy based reconstruction for partial volume correction in brain FDG-PET

The inhibitory neurotransmitter glycine modulates macrophage activity by activation of neutral amino acid transporters

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