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Nucleophilic (Radio)Fluorination of Redox-Active Esters via Radical-Polar Crossover Enabled by Photoredox Catalysis

Journal of the American Chemical Society, 2020-05, Vol.142 (20), p.9493-9500

2020

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The discovery and evaluation of [18F]BMS-986229, a novel macrocyclic peptide PET radioligand for the measurement of PD-L1 expression and in-vivo PD-L1 target engagement

European journal of nuclear medicine and molecular imaging, 2024-03, Vol.51 (4), p.978-990

2024

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Synthesis of stable‐isotope‐labeled N‐(3‐dimethylaminopropyl)‐N′‐ethylcarbodiimide and N‐(3‐dimethylaminopropyl)‐N′‐ethylurea

Journal of labelled compounds & radiopharmaceuticals, 2020-11, Vol.63 (13), p.526-530

2020

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Metabolism and disposition of dasatinib after oral administration to humans

Drug metabolism and disposition, 2008-07, Vol.36 (7), p.1357

2008

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Characterization of the in vitro and in vivo metabolism and disposition and cytochrome P450 inhibition/induction profile of saxagliptin in human

Drug metabolism and disposition, 2012-07, Vol.40 (7), p.1345

2012

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Synthesis and Preclinical Evaluation of a 68Ga-Labeled Adnectin, 68Ga-BMS-986192, as a PET Agent for Imaging PD-L1 Expression

The Journal of nuclear medicine (1978), 2021-09, Vol.62 (9), p.1228-1234

2021

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Tissue distribution and tumor uptake of folate receptor–targeted epothilone folate conjugate,BMS-753493,in CD2F1 mice after systemic administration

Acta pharmaceutica Sinica. B, 2016-09, Vol.6 (5), p.460-467

2016

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Reductive isoxazole ring opening of the anticoagulant razaxaban is the major metabolic clearance pathway in rats and dogs

Drug metabolism and disposition, 2008-02, Vol.36 (2), p.303

2008

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Biotransformation of [14C]dasatinib: in vitro studies in rat, monkey, and human and disposition after administration to rats and monkeys

Drug metabolism and disposition, 2008-07, Vol.36 (7), p.1341

2008

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Synthesis and Preclinical Evaluation of a 68 Ga-Labeled Adnectin, 68 Ga-BMS-986192, as a PET Agent for Imaging PD-L1 Expression

Journal of Nuclear Medicine, 2021-09, Vol.62 (9), p.1228-1234

2021

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Development, Characterization, and Radiation Dosimetry Studies of 18F-BMS-986229, a 18F-Labeled PD-L1 Macrocyclic Peptide PET Tracer

Molecular imaging and biology, 2024-04, Vol.26 (2), p.301-309

2024

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Biotransformation Profiling of [14C]Ixabepilone in Human Plasma, Urine and Feces Samples Using Accelerator Mass Spectrometry (AMS)

DRUG METABOLISM AND PHARMACOKINETICS, 2009-01, Vol.24 (6), p.511-522

2009

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Metabolism of [14C]gemopatrilat after oral administration to rats, dogs, and humans

Drug metabolism and disposition, 2006-06, Vol.34 (6), p.961

2006

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Synthesis of [D4]- and [D7]-4β-hydroxycholesterols for use in a novel drug-drug interaction assay

Journal of labelled compounds & radiopharmaceuticals, 2012-02, Vol.55 (2), p.61-65

2012

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Synthesis and Biologic Evaluation of a Novel 18 F-Labeled Adnectin as a PET Radioligand for Imaging PD-L1 Expression

Journal of Nuclear Medicine, 2018-03, Vol.59 (3), p.529-535

2018

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The synthesis of 14C-labeled N-succinimidyl-3-maleimidopropionate, a linker molecule for PEGylated biologics

Journal of labelled compounds & radiopharmaceuticals, 2014-10, Vol.57 (12), p.667-669

2014

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The synthesis of 14C-labeled, 13CD2-labeled saxagliptin, and its 13CD2-labeled 5-hydroxy metabolite

Journal of labelled compounds & radiopharmaceuticals, 2014-03, Vol.57 (3), p.136-140

2014

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Synthesis of 14C-labeled and 13C-,15N-labeled dasatinib and its piperazine N-dealkyl metabolite

Journal of labelled compounds & radiopharmaceuticals, 2008-01, Vol.51 (1), p.41-47

2008

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Synthesis of an adenine N-3 substituted CBI adduct by alkylation of adenine with a 1-iodomethylindoline seco-CBI precursor

Tetrahedron, 2018-11, Vol.74 (46), p.6680-6688

2018

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A facile and efficient synthesis of d3-labelled Reyataz

Journal of labelled compounds & radiopharmaceuticals, 2005-12, Vol.48 (14), p.1041-1047

2005

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The 14C, 13C, and 15N syntheses of a potent VEGFR-2 kinase inhibitor, Brivanib, and its prodrug, Brivanib Alaninate

Journal of labelled compounds & radiopharmaceuticals, 2011-05, Vol.54 (6), p.324-331

2011

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Synthesis of isotopically labeled daclatasvir for use in human clinical studies: J. Easter et al

Journal of labelled compounds & radiopharmaceuticals, 2016-04, Vol.59 (4), p.164-170

2016

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Abstract 2479: Preclinical assessment of imaging agents for identification of fucosyl-GM1 expression in vivo

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.2479-2479

2022

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Abstract 871: [18F]BMS-986192 as a novel PET imaging agent for assessment of PD-L1 expression in vivo

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.871-871

2017

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Whole body PD-L1 PET in patients with NSCLC and melanoma

Journal of clinical oncology, 2018-02, Vol.36 (5_suppl), p.139-139

2018

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Nucleophilic (Radio)Fluorination of Redox-Active Esters via Radical-Polar Crossover Enabled by Photoredox Catalysis

The discovery and evaluation of [18F]BMS-986229, a novel macrocyclic peptide PET radioligand for the measurement of PD-L1 expression and in-vivo PD-L1 target engagement

Synthesis of stable‐isotope‐labeled N‐(3‐dimethylaminopropyl)‐N′‐ethylcarbodiimide and N‐(3‐dimethylaminopropyl)‐N′‐ethylurea

Metabolism and disposition of dasatinib after oral administration to humans

Characterization of the in vitro and in vivo metabolism and disposition and cytochrome P450 inhibition/induction profile of saxagliptin in human

Synthesis and Preclinical Evaluation of a 68Ga-Labeled Adnectin, 68Ga-BMS-986192, as a PET Agent for Imaging PD-L1 Expression

Tissue distribution and tumor uptake of folate receptor–targeted epothilone folate conjugate,BMS-753493,in CD2F1 mice after systemic administration

Reductive isoxazole ring opening of the anticoagulant razaxaban is the major metabolic clearance pathway in rats and dogs

Biotransformation of [14C]dasatinib: in vitro studies in rat, monkey, and human and disposition after administration to rats and monkeys

Synthesis and Preclinical Evaluation of a 68 Ga-Labeled Adnectin, 68 Ga-BMS-986192, as a PET Agent for Imaging PD-L1 Expression

Development, Characterization, and Radiation Dosimetry Studies of 18F-BMS-986229, a 18F-Labeled PD-L1 Macrocyclic Peptide PET Tracer

Biotransformation Profiling of [14C]Ixabepilone in Human Plasma, Urine and Feces Samples Using Accelerator Mass Spectrometry (AMS)

Metabolism of [14C]gemopatrilat after oral administration to rats, dogs, and humans

Synthesis of [D4]- and [D7]-4β-hydroxycholesterols for use in a novel drug-drug interaction assay

Synthesis and Biologic Evaluation of a Novel 18 F-Labeled Adnectin as a PET Radioligand for Imaging PD-L1 Expression

The synthesis of 14C-labeled N-succinimidyl-3-maleimidopropionate, a linker molecule for PEGylated biologics

The synthesis of 14C-labeled, 13CD2-labeled saxagliptin, and its 13CD2-labeled 5-hydroxy metabolite

Synthesis of 14C-labeled and 13C-,15N-labeled dasatinib and its piperazine N-dealkyl metabolite

Synthesis of an adenine N-3 substituted CBI adduct by alkylation of adenine with a 1-iodomethylindoline seco-CBI precursor

A facile and efficient synthesis of d3-labelled Reyataz

The 14C, 13C, and 15N syntheses of a potent VEGFR-2 kinase inhibitor, Brivanib, and its prodrug, Brivanib Alaninate

Synthesis of isotopically labeled daclatasvir for use in human clinical studies: J. Easter et al

Abstract 2479: Preclinical assessment of imaging agents for identification of fucosyl-GM1 expression in vivo

Abstract 871: [18F]BMS-986192 as a novel PET imaging agent for assessment of PD-L1 expression in vivo

Whole body PD-L1 PET in patients with NSCLC and melanoma

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