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Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10

Immunity (Cambridge, Mass.), 2016-01, Vol.44 (1), p.21-31

2016

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Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design

PLoS pathogens, 2017-02, Vol.13 (2), p.e1006212

2017

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Structural basis of hepatitis C virus neutralization by broadly neutralizing antibody HCV1

Proceedings of the National Academy of Sciences - PNAS, 2012-06, Vol.109 (24), p.9499-9504

2012

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Structure of a V3-Containing HIV-1 gp120 Core

Science (American Association for the Advancement of Science), 2005-11, Vol.310 (5750), p.1025-1028

2005

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Antibody vs. HIV in a Clash of Evolutionary Titans

Proceedings of the National Academy of Sciences - PNAS, 2005-10, Vol.102 (42), p.14943-14948

2005

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Structure of Hepatitis C Virus Envelope Glycoprotein E2 Antigenic Site 412 to 423 in Complex with Antibody AP33

Journal of Virology, 2012-12, Vol.86 (23), p.13085-13088

2012

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Defining the Structural Basis for Allosteric Product Release from E. coli Dihydrofolate Reductase Using NMR Relaxation Dispersion

Journal of the American Chemical Society, 2017-08, Vol.139 (32), p.11233-11240

2017

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Broadly Neutralizing Anti-HIV Antibody 4E10 Recognizes a Helical Conformation of a Highly Conserved Fusion-Associated Motif in gp41

Immunity (Cambridge, Mass.), 2005-02, Vol.22 (2), p.163-173

2005

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Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers

Scientific reports, 2017-08, Vol.7 (1), p.8390-15, Article 8390

2017

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Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign

Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (7), p.E738-E747

2014

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Antibody Domain Exchange Is an Immunological Solution to Carbohydrate Cluster Recognition

Science (American Association for the Advancement of Science), 2003-06, Vol.300 (5628), p.2065-2071

2003

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Crystal Structure of a Neutralizing Human IgG against HIV-1: A Template for Vaccine Design

Science (American Association for the Advancement of Science), 2001-08, Vol.293 (5532), p.1155-1159

2001

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A Conformational Switch in Human Immunodeficiency Virus gp41 Revealed by the Structures of Overlapping Epitopes Recognized by Neutralizing Antibodies

Journal of Virology, 2009-09, Vol.83 (17), p.8451-8462

2009

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Crystal Structures of Human Immunodeficiency Virus Type 1 (HIV-1) Neutralizing Antibody 2219 in Complex with Three Different V3 Peptides Reveal a New Binding Mode for HIV-1 Cross-Reactivity

Journal of Virology, 2006-06, Vol.80 (12), p.6093-6105

2006

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A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

Science (American Association for the Advancement of Science), 2011-11, Vol.334 (6059), p.1097-1103

2011

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Cofactor-Mediated Conformational Dynamics Promote Product Release From Escherichia coli Dihydrofolate Reductase via an Allosteric Pathway

Journal of the American Chemical Society, 2015-07, Vol.137 (29), p.9459-9468

2015

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Crystal Structure of a Shark Single-Domain Antibody V Region in Complex with Lysozyme

Science (American Association for the Advancement of Science), 2004-09, Vol.305 (5691), p.1770-1773

2004

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Recurring conformation of the human immunodeficiency virus type 1 gp120 V3 loop

Virology (New York, N.Y.), 2003-10, Vol.315 (1), p.159-173

2003

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Antibody Structure

Microbiology spectrum, 2014-04, Vol.2 (2)

2014

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MHC restriction: slip-sliding away

Nature immunology, 2005-05, Vol.6 (5), p.434-435

2005

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Crystal Structure of the Principal Neutralization Site of HIV-1

Science (American Association for the Advancement of Science), 1994-04, Vol.264 (5155), p.82-85

1994

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Crystal Structure of a Human Immunodeficiency Virus Type 1 Neutralizing Antibody, 50.1, in Complex with Its V3 Loop Peptide Antigen

Proceedings of the National Academy of Sciences - PNAS, 1993-07, Vol.90 (13), p.6325-6329

1993

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Crystal Structures of an Antibody to a Peptide and Its Complex with Peptide Antigen at 2.8 Å

Science (American Association for the Advancement of Science), 1990-05, Vol.248 (4956), p.712-719

1990

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Structural studies of human HIV-1 V3 antibodies

Human antibodies, 2005, Vol.14 (3-4), p.73-80

2005

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Antigen-induced conformational changes in antibodies: A problem for structural prediction and design

Trends in Biotechnology, 1994-07, Vol.12 (7), p.275-279

1994

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Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10

Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design

Structural basis of hepatitis C virus neutralization by broadly neutralizing antibody HCV1

Structure of a V3-Containing HIV-1 gp120 Core

Antibody vs. HIV in a Clash of Evolutionary Titans

Structure of Hepatitis C Virus Envelope Glycoprotein E2 Antigenic Site 412 to 423 in Complex with Antibody AP33

Defining the Structural Basis for Allosteric Product Release from E. coli Dihydrofolate Reductase Using NMR Relaxation Dispersion

Broadly Neutralizing Anti-HIV Antibody 4E10 Recognizes a Helical Conformation of a Highly Conserved Fusion-Associated Motif in gp41

Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers

Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign

Antibody Domain Exchange Is an Immunological Solution to Carbohydrate Cluster Recognition

Crystal Structure of a Neutralizing Human IgG against HIV-1: A Template for Vaccine Design

A Conformational Switch in Human Immunodeficiency Virus gp41 Revealed by the Structures of Overlapping Epitopes Recognized by Neutralizing Antibodies

Crystal Structures of Human Immunodeficiency Virus Type 1 (HIV-1) Neutralizing Antibody 2219 in Complex with Three Different V3 Peptides Reveal a New Binding Mode for HIV-1 Cross-Reactivity

A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

Cofactor-Mediated Conformational Dynamics Promote Product Release From Escherichia coli Dihydrofolate Reductase via an Allosteric Pathway

Crystal Structure of a Shark Single-Domain Antibody V Region in Complex with Lysozyme

Recurring conformation of the human immunodeficiency virus type 1 gp120 V3 loop

Antibody Structure

MHC restriction: slip-sliding away

Crystal Structure of the Principal Neutralization Site of HIV-1

Crystal Structure of a Human Immunodeficiency Virus Type 1 Neutralizing Antibody, 50.1, in Complex with Its V3 Loop Peptide Antigen

Crystal Structures of an Antibody to a Peptide and Its Complex with Peptide Antigen at 2.8 Å

Structural studies of human HIV-1 V3 antibodies

Antigen-induced conformational changes in antibodies: A problem for structural prediction and design

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